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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
UT-B
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "UT-B" in MCE Product Catalog:
1
1 Cited Publications
Target:
Research Areas:
UT-B-IN-1 (UTBINH-14) is a reversible, competitive and selective urea transporter-B (UT-B) inhibitor with IC50 values of 10 and 25 nM for human and mouse UT-B, respectively. UT-B-IN-1 shows low toxicity and high selectivity for UT-B over UT-A isoforms. UT-B-IN-1 increases urine output and reduces urine osmolality of mice. UT-B-IN-1 can be used for diuretic mechanism research .
Cat. No.: HY-184585
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Research Areas:
UT-B-IN-2 is an orally active UT-B inhibitor, with an IC50 of 0.11 μM in mice and 0.054 μM in rats. UT-B-IN-2 induces diuretic effects in rats. UT-B-IN-2 can be used in the research of cardiovascular diseases and edema-related diseases .
Cat. No.: HY-RS16218
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Research Areas:
SLC14A1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for SLC14A1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-116718
CAS No.: 892745-28-7
Target:
Research Areas:
UTA1inh-D1 is a selective UT-A1 and UT-B urea transporter inhibitor with IC50 values of 3.8 μM and 15 μM, respectively. UTA1inh-D1 is promising for research of refractory edema, such as congestive heart failure and cirrhosis .
Cat. No.: HY-124107
CAS No.: 1251688-22-8
Target:
Research Areas:
UTA1inh-A1 is a urea transporter (UT) inhibitor. UTA1inh-A1 has IC50 values of 3.3 μM and 16 μM for UT-A1 and UT-B. UTA1inh-A1 can be used in research related to urearetics .
Cat. No.: HY-RS27773
Target:
Research Areas:
Slc14a1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Slc14a1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P706342
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SLC14A1; SolUTe Carrier Family 14 (Urea Transporter), Member 1; Prev. JK; Urea Transporter JK Glycoprotein; RACH1; MUTant KIDD Blood Group Antigen; Urea Transporter, Erythrocyte; Truncated Kidd Blood Group; Urea Transporter 1; Urea Transporter-B1; HsT1341; Kidd Blood Group; RACH2; Urea Transporter; SolUTe Carrier Family 14 (Urea Transporter), Member 1 (Kidd Blood Group); SLC14A1 JK; SolUTe Carrier Family 14 Member 1; HUT11A; Kidd Blood Group Antigen; Jk(A); HUT11; Jk(B); UT1; UT-B1; UTE; SolUTe Carrier Family 14 Member 1 (Kidd Blood Group); Truncated SolUTe Carrier Family 14
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
