8

α-Tocopherol phosphate

8 Publications Verification

Cat. No.: HY-16686

CAS No.: 38976-17-9

Synonyms: alpha-Tocopherol phosphate; TocP; vitamin E phosphate

Target:

Apoptosis Reactive Oxygen Species (ROS)

Research Areas:

Cancer

α-Tocopherol phosphate is an antioxidant that protects against long-wave UVA1 induced cell death and scavenge UVA1 induced ROS in a skin cell model. α-Tocopherol phosphate exhibits angiogenesis-promoting activity .

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8

α-Tocopherol phosphate disodium

8 Publications Verification

Cat. No.: HY-W127530

CAS No.: 60934-46-5

Synonyms: alpha-Tocopherol phosphate disodium; TocP disodium; Vitamin E phosphate disodium

α-Tocopherol phosphate disodium is an antioxidant that protects against long-wave UVA1 induced cell death and scavenge UVA1 induced ROS in a skin cell model. α-Tocopherol phosphate disodium exhibits angiogenesis-promoting activity .

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3

Pefloxacin

3 Cited Publications

Cat. No.: HY-B0147

CAS No.: 70458-92-3

Synonyms: Pefloxacinium

Category:

Infection Disease Research Fields

Target:

Antibiotic Bacterial Parasite DNA/RNA Synthesis Topoisomerase

Pefloxacin (Pefloxacinium) is a broad spectrum antibiotic. Pefloxacin blocks DNA replication by inhibiting DNA gyrase. Pefloxacin inhibits DNA relaxation catalyzed by topoisomerase I with an IC₅₀ of 45 μg/mL. Pefloxacin exhibits antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, and Bacteroides fragilis with MIC₉₀s of 0.12, 4, and 16 mg/L, respectively. Pefloxacin has anti-Plasmodium yoelii infection activity. Pefloxacin increase UVA-induced edema and immunesuppression. Pefloxacin can be used for infection studies .

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3

Pefloxacin mesylate

3 Cited Publications

Cat. No.: HY-B0147A

CAS No.: 70458-95-6

Synonyms: Pefloxacinium mesylate

Target:

Topoisomerase DNA/RNA Synthesis Antibiotic Bacterial Parasite

Research Areas:

Infection Inflammation/Immunology

Pefloxacin (Pefloxacinium) mesylate is a broad spectrum antibiotic. Pefloxacin blocks DNA replication by inhibiting DNA gyrase. Pefloxacin mesylate inhibits DNA relaxation catalyzed by topoisomerase I with an IC₅₀ of 45 μg/mL. Pefloxacin mesylate exhibits antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, and Bacteroides fragilis with MIC₉₀s of 0.12, 4, and 16 mg/L, respectively. Pefloxacin mesylate has anti-Plasmodium yoelii infection activity. Pefloxacin mesylate increase UVA-induced edema and immunesuppression. Pefloxacin mesylate can be used for infection studies .

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3

Pefloxacin mesylate dihydrate

3 Cited Publications

Cat. No.: HY-B0147B

CAS No.: 149676-40-4

Synonyms: Pefloxacinium mesylate dihydrate

Target:

Topoisomerase DNA/RNA Synthesis Antibiotic Bacterial Parasite

Research Areas:

Infection Inflammation/Immunology

Pefloxacin (Pefloxacinium) mesylate dihydrate is a broad spectrum antibiotic. Pefloxacin mesylate dihydrate blocks DNA replication by inhibiting DNA gyrase. Pefloxacin mesylate dihydrate inhibits DNA relaxation catalyzed by topoisomerase I with an IC₅₀ of 45 μg/mL. Pefloxacin mesylate dihydrate exhibits antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, and Bacteroides fragilis with MIC₉₀s of 0.12, 4, and 16 mg/L, respectively. Pefloxacin mesylate dihydrate has anti-Plasmodium yoelii infection activity. Pefloxacin mesylate dihydrate increase UVA-induced edema and immunesuppression. Pefloxacin mesylate dihydrate can be used for infection studies .

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2

Octocrylene

2 Cited Publications

Cat. No.: HY-A0087

CAS No.: 6197-30-4

Target:

Environmental Pollutants PPAR Estrogen Receptor/ERR Biochemical Assay Reagents Cytochrome P450

Research Areas:

Others

Octocrylene is an organic ultraviolet (UV) filter that absorbs mainly UVB radiation and shorter UVA wavelengths. Octocrylene acts as a partial agonist of PPARγ, which alters the gene transcription profile of lipid metabolism enzymes. In addition, Octocrylene is cytotoxic and genotoxic to human skin fibroblasts and mediates the biosynthesis of estrogens such as estriol in zebrafish larvae, while affecting antioxidant pathways including glutathione transferase and peroxisomes .

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