1538 Results for "

VEGF-PLAP secretion

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530

BAY 11-7082

530 Publications Verification

Cat. No.: HY-13453

CAS No.: 19542-67-7

Purity: 99.98%

Synonyms: BAY 11-7821

Target:

IKK Deubiquitinase Autophagy Apoptosis NF-κB

Research Areas:

Inflammation/Immunology Cancer

BAY 11-7082 is an IκBα phosphorylation and NF-κB inhibitor. BAY 11-7082 selectively and irreversibly inhibits the TNF-α-induced phosphorylation of IκB-α, and decreases NF-κB and expression of adhesion molecules. BAY 11-7082 inhibits ubiquitin-specific protease USP7 and USP21 (IC₅₀=0.19, 0.96 μM, respectively). BAY 11-7082 inhibits gasdermin D (GSDMD) pore formation in liposomes and inflammasome-mediated pyroptosis and IL-1β secretion in human and mouse cells .

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182

ATP

182 Cited Publications

Cat. No.: HY-B2176

CAS No.: 56-65-5

Synonyms: Adenosine 5'-triphosphate

Category:

Plants Other Families Extract Endogenous metabolite Alkaloids Human Gut Microbiota Metabolites Microorganisms Animals Other Alkaloids Disease Research Fields Inflammation/Immunology

Target:

Endogenous Metabolite NOD-like Receptor (NLR) Interleukin Related Bacterial

ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation. ATP can activate the NLRP3 inflammasome and induce IL-1β and chemokines secretion. ATP has anti-bacterial infection effects and can protect mice against bacterial infection in mice .

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182

ATP dimagnesium

182 Cited Publications

Cat. No.: HY-B2176B

CAS No.: 74804-12-9

Synonyms: Adenosine 5'-triphosphate dimagnesium

Category:

Natural Products Endogenous metabolite Disease Research Fields Inflammation/Immunology

Target:

Endogenous Metabolite NOD-like Receptor (NLR) Interleukin Related Bacterial

ATP (Adenosine 5'-triphosphate) dimagnesium is a central component of energy storage and metabolism in vivo. ATP dimagnesium provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP dimagnesium is an important endogenous signaling molecule in immunity and inflammation. ATP dimagnesium can activate the NLRP3 inflammasome and induce IL-1β and chemokines secretion. ATP dimagnesium has anti-bacterial infection effects and can protect mice against bacterial infection in mice .

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182

ATP disodium trihydrate

182 Cited Publications

Cat. No.: HY-B2176A

CAS No.: 51963-61-2

Synonyms: Adenosine-5'-triphosphate disodium trihydrate

Category:

Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Inflammation/Immunology

Target:

Endogenous Metabolite NOD-like Receptor (NLR) Interleukin Related Bacterial

ATP (Adenosine 5'-triphosphate) disodium trihydrate is a central component of energy storage and metabolism in vivo. ATP disodium trihydrate provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium trihydrate is an important endogenous signaling molecule in immunity and inflammation. ATP disodium trihydrate can activate the NLRP3 inflammasome and induce IL-1β and chemokines secretion. ATP disodium trihydrate has anti-bacterial infection effects and can protect mice against bacterial infection in mice .

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175

ATP disodium salt hydrate

175 Cited Publications

Cat. No.: HY-W010735

CAS No.: 34369-07-8

Synonyms: Adenosine 5'-triphosphate disodium salt hydrate

Category:

Microorganisms Animals Ketones, Aldehydes, Acids Plants Other Families Extract Endogenous metabolite Disease Research Fields Inflammation/Immunology

Target:

Endogenous Metabolite NOD-like Receptor (NLR) Interleukin Related Bacterial

ATP (Adenosine 5'-triphosphate) disodium salt hydrate is a central component of energy storage and metabolism in vivo. ATP disodium salt hydrate provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium salt hydrate is an important endogenous signaling molecule in immunity and inflammation. ATP disodium salt hydrate can activate the NLRP3 inflammasome and induce IL-1β and chemokines secretion. ATP disodium salt hydrate has anti-bacterial infection effects and can protect mice against bacterial infection in mice .

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172

ATP dipotassium

172 Cited Publications

Cat. No.: HY-B2176C

CAS No.: 42373-41-1

Synonyms: Adenosine 5'-triphosphate dipotassium

Category:

Animals Ketones, Aldehydes, Acids Plants Other Families Extract Endogenous metabolite Disease Research Fields Inflammation/Immunology

Target:

Endogenous Metabolite NOD-like Receptor (NLR) Interleukin Related Bacterial

ATP (Adenosine 5'-triphosphate) dipotassium is a central component of energy storage and metabolism in vivo. ATP dipotassium provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP dipotassium is an important endogenous signaling molecule in immunity and inflammation. ATP dipotassium can activate the NLRP3 inflammasome and induce IL-1β and chemokines secretion. ATP dipotassium has anti-bacterial infection effects and can protect mice against bacterial infection in mice .

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172

ATP magnesium

172 Cited Publications

Cat. No.: HY-B2176E

CAS No.: 1476-84-2

Synonyms: Adenosine 5'-triphosphate magnesium

Target:

Endogenous Metabolite NOD-like Receptor (NLR) Interleukin Related Bacterial

ATP (Adenosine 5'-triphosphate) magnesium is a central component of energy storage and metabolism in vivo. ATP magnesium provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP magnesium is an important endogenous signaling molecule in immunity and inflammation. ATP magnesium can activate the NLRP3 inflammasome and induce IL-1β and chemokines secretion. ATP magnesium has anti-bacterial infection effects and can protect mice against bacterial infection in mice .

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172

ATP disodium salt, 100 mM Solution, PCR Grade

172 Cited Publications

Cat. No.: HY-B2176I

CAS No.: 987-65-5

Synonyms: Adenosine 5'-triphosphate disodium salt, 100 mM Solution, PCR Grade

ATP (Adenosine 5'-triphosphate) disodium salt, 100 mM Solution, PCR Grade is a central component of energy storage and metabolism in vivo. ATP disodium salt, 100 mM Solution, PCR Grade provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium salt, 100 mM Solution, PCR Grade is an important endogenous signaling molecule in immunity and inflammation. ATP disodium salt, 100 mM Solution, PCR Grade can activate the NLRP3 inflammasome and induce IL-1β and chemokines secretion. ATP disodium salt, 100 mM Solution, PCR Grade has anti-bacterial infection effects and can protect mice against bacterial infection in mice .

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170

Disulfiram

170 Cited Publications

Cat. No.: HY-B0240

CAS No.: 97-77-8

Synonyms: Tetraethylthiuram disulfide; TETD

Target:

Aldehyde Dehydrogenase (ALDH) Interleukin Related Pyroptosis Apoptosis Cuproptosis

Research Areas:

Metabolic Disease Cancer

Disulfiram (Tetraethylthiuram disulfide) is a specific inhibitor of aldehyde-dehydrogenase (ALDH1), used for the treatment of chronic alcoholism by producing an acute sensitivity to alcohol. Disulfiram inhibits gasdermin D (GSDMD) pore formation in liposomes and inflammasome-mediated pyroptosis and IL-1β secretion in human and mouse cells. Disulfiram, a copper ion carrier, with Cu ²⁺ increases intracellular ROS levels and induces cuproptosis .

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Shikonin

76 Cited Publications

Cat. No.: HY-N0822

CAS No.: 517-89-5

Synonyms: C.I. 75535; Isoarnebin 4

Category:

Quinones Boraginaceae Extract Plants 500 - Internal Server Error | MedChemExpress

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