102

102 Publications Verification

Target:

Research Areas:

Isoprenaline is a non-selective, orally active β-adrenergic receptor agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma .

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102

Isoprenaline hemisulfate

102 Publications Verification

Cat. No.: HY-108353A

CAS No.: 299-95-6

Category:

Cardiovascular Disease Disease Research Fields Endocrinology

Target:

Adrenergic Receptor

Isoprenaline hemisulfate is a non-selective, orally active β-adrenergic receptor agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma .

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102

Isoprenaline hydrochloride

102 Publications Verification

Cat. No.: HY-B0468

CAS No.: 51-30-9

Synonyms: Isoproterenol hydrochloride

Category:

Cardiovascular Disease Disease Research Fields Endocrinology

Target:

Adrenergic Receptor

Isoprenaline (Isoproterenol) hydrochloride is a non-selective, orally active β-adrenergic receptor agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma .

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37

Milrinone

37 Cited Publications

Cat. No.: HY-14252

CAS No.: 78415-72-2

Purity: 99.80%

Synonyms: Win 47203

Target:

Phosphodiesterase (PDE)

Research Areas:

Cardiovascular Disease

Milrinone is a PDE3 inhibitor, and also an inotrope and vasodilator.

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29

Fasudil Hydrochloride

29 Cited Publications

Cat. No.: HY-10341

CAS No.: 105628-07-7

Purity: 99.97%

Synonyms: HA-1077 Hydrochloride; AT-877 Hydrochloride

Target:

ROCK Calcium Channel Autophagy PKA PKC HIV

Research Areas:

Cancer

Fasudil (HA-1077; AT877) Hydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an K_i of 0.33 μM for ROCK1, IC₅₀s of 0.158 μM and 4.58 μM, 12.30 μM, 1.650 μM for ROCK2 and PKA, PKC, PKG, respectively. Fasudil Hydrochloride is also a potent Ca ²⁺ channel antagonist and vasodilator .

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29

Fasudil

29 Cited Publications

Cat. No.: HY-10341A

CAS No.: 103745-39-7

Synonyms: HA-1077; AT877

Target:

ROCK Calcium Channel Autophagy PKA PKC

Research Areas:

Cancer

Fasudil (HA-1077; AT877) is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an K_i of 0.33 μM for ROCK1, IC₅₀s of 0.158 μM and 4.58 μM, 12.30 μM, 1.650 μM for ROCK2 and PKA, PKC, PKG, respectively. Fasudil is also a potent Ca ²⁺ channel antagonist and vasodilator .

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29

Fasudil dihydrochloride

29 Cited Publications

Cat. No.: HY-10341C

CAS No.: 203911-27-7

Synonyms: HA-1077 dihydrochloride; AT-877 dihydrochloride

Target:

Calcium Channel ROCK PKA PKC Autophagy HIV

Research Areas:

Cancer

Fasudil (HA-1077; AT877) dihydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an K_i of 0.33 μM for ROCK1, IC₅₀s of 0.158 μM and 4.58 μM, 12.30 μM, 1.650 μM for ROCK2 and PKA, PKC, PKG, respectively. Fasudil dihydrochloride is also a potent Ca ²⁺ channel antagonist and vasodilator .

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27

L-Arginine

27 Cited Publications

Cat. No.: HY-N0455

CAS No.: 74-79-3

Category:

Cardiovascular Disease Amino acids Endogenous metabolite Disease Research Fields Cancer

Target:

NO Synthase Endogenous Metabolite

L-Arginine ((S)-(+)-Arginine) is the substrate for the endothelial nitric oxide synthase (eNOS) to generate NO. L-Arginine is transported into vascular smooth muscle cells by the cationic amino acid transporter family of proteins where it is metabolized to nitric oxide (NO), polyamines, or L-proline. L-Arginine is a potent vasodilator, and can be used to induce experimental acute pancreatitis .

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27

L-Arginine hydrochloride

27 Cited Publications

Cat. No.: HY-N0455A

CAS No.: 1119-34-2

Synonyms: (S)-(+)-Arginine hydrochloride

Category:

Natural Products Other Diseases Endogenous metabolite Disease Research Fields

Target:

NO Synthase Endogenous Metabolite

L-Arginine ((S)-(+)-Arginine) is the substrate for the endothelial nitric oxide synthase (eNOS) to generate NO. L-Arginine is transported into vascular smooth muscle cells by the cationic amino acid transporter family of proteins where it is metabolized to nitric oxide (NO), polyamines, or L-proline. L-Arginine is a potent vasodilator, and can be used to induce experimental acute pancreatitis .

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