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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
WZS0347
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "WZS0347" in MCE Product Catalog:
Cat. No.: HY-179717
Research Areas:
WZS0347 is a MITF PROTAC degrader. WZS0347 effectively reduces MITF protein levels in various melanoma cell lines. WZS0347 induces MITF degradation via the cereblon-dependent ubiquitin-proteasome pathway, downregulates the expression of downstream target genes of MITF, and inhibits the colony formation and migration abilities of cancer cells. WZS0347 can be used in melanoma-related research .
Cat. No.: HY-179718
Research Areas:
TT-012-Br (Compound 4) is a ligand for MITF and can be used for the synthesis of PROTACs, such as WZS0347 (HY-179717) .
Cat. No.: HY-179720
Research Areas:
WZS0347 Ligand-Linker Conjugate 1 (Compound 5d) is a synthetic target protein ligand-linker conjugate, which can be used for the synthesis of PROTACs, such as WZS0347 (HY-179717). WZS0347 is a potent MITF PROTAC degrader with anti-cancer activity .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
