19 Results for "

Withania

" in MedChemExpress (MCE) Product Catalog:
Products (19)

19 Results for "Withania" in MCE Product Catalog:

14
14 Publications Verification
Cat. No.: HY-N2065
CAS No.: 5119-48-2
Withaferin A is a steroidal lactone isolated from Withania somnifera, inhibits NF-kB activation and targets vimentin, with potent antiinflammatory and anticancer activities. Withaferin A is an inhibitor of endothelial protein C receptor (EPCR) shedding.
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1 Cited Publications
Cat. No.: HY-129692
CAS No.: 27570-38-3
Purity:  93.06%
Withanone is an active ingredient from the roots of Withania somnifera and a GRP75 inhibitor. Withanone has multifunctional neuroprotective effects in alleviating cognitive dysfunction. In neuron-like cells, Withanone can inhibit NMDA-induced excitotoxicity. Withanone can inhibit white adipose tissue browning by blocking the formation of the GRP75-ANT2-UCP1 complex, thereby alleviating cancer-related cachexia. Withanone can be used in the research of tumors and nervous system diseases .
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1 Cited Publications
Cat. No.: HY-N5069
CAS No.: 173614-88-5
2,3-Didehydrosomnifericin is one of withanolides found in Withania somnifera .
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Cat. No.: HY-N2065R
CAS No.: 5119-48-2
Withaferin A (Standard) is the analytical standard of Withaferin A. This product is intended for research and analytical applications. Withaferin A is a steroidal lactone isolated from Withania somnifera, inhibits NF-kB activation and targets vimentin, with potent antiinflammatory and anticancer activities. Withaferin A is an inhibitor of endothelial protein C receptor (EPCR) shedding.
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Cat. No.: HY-N5120
CAS No.: 5589-41-3
Synonyms: 2,3-Dihydrowithaferin A
Dihydrowithaferin A (2, 3-dihydrowithaferin A) is a withanolide isolated from Withania somnifera. Dihydrowithaferin A is active against acetylcholinesterase (AChE) .
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Cat. No.: HY-P11032
CAS No.: 3106022-48-1
Target:  

SARS-CoV Virus Protease

Research Areas:  

Infection

Mp-4D7-pF2, a cell-penetrating bicyclic peptide, is a noncovalent SARS-CoV-2 main protease inhibitor with an IC50 of 4.51 μM. Mp-4D7-pF2 has an antiviral activity against SARS-CoV-2 with no cytotoxicity. Mp-4D7-pF2 can used for COVID-19 infections research .
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Cat. No.: HY-N5131
CAS No.: 73365-94-3
Synonyms: Quresimin A
3β-Methoxy-2,3-dihydrowithaferin A is one of withanolides found in Withania somnifera .
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Cat. No.: HY-N10884
CAS No.: 2365386-74-7
Withasomniferolide A is a withanolide, isolated from a GABAA receptor positive activator methanol extract of the roots of Withania somnifera .
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Cat. No.: HY-N10887
CAS No.: 2365386-75-8
Withasomniferolide B is a withanolide. Withasomniferolide B can be isolated from a GABAA receptor positive activator methanol extract of the roots of Withania somnifera .
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Cat. No.: HY-138146
CAS No.: 6850-30-2
Synonyms: 4-oxo Withaferin A
4-Dehydrowithaferin A is the analogue of withaferin A. Withaferin A is a withanolide isolated from Withania somnifera. 4-Dehydrowithaferin A has the potential for the research of multiple myeloma .
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Cat. No.: HY-N11702
CAS No.: 114924-89-9
Kaempferol-3-O-robinoside-7-Oglucoside is a double-chain flavonol triglycoside can be extracted from Withania somnifera .
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Cat. No.: HY-N18728
CAS No.: 90147-43-6
Category:  

Extract

Target:  

Others

Withania somnifera extract, derived from the South African ashwagandha (Withania somnifera), contains a variety of bioactive components, including solanolactones (such as solanolactone A, solanolactone D, and solanine A), solanosin (such as solanosin IV and solanosin VI), alkaloids (such as isopretiline and anaflin), β-sitosterol, benzoic acid, and tropane alkaloids. Withania somnifera extract has been extensively studied for its benefits in stress management, anxiety relief, improved physical function, and overall health.
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Cat. No.: HY-N15635
CAS No.: 119539-81-0
Synonyms: (+)-Withacoagin
Withacoagin is a withanolide that can be isolated from the roots of Withania coagulans. Withacoagin has various biological activites such as adaptogenic, anti-inflammatory, and antioxidant properties. Withacoagin regulates the activity of various enzymes and pathways related to oxidative stress and inflammation. Withacoagin can attenuates HIV-1 infection .
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Cat. No.: HY-129692R
CAS No.: 27570-38-3
Withanone (Standard) is the analytical standard of Withanone (HY-129692). This product is intended for research and analytical applications. Withanone is an active ingredient from the roots of Withania somnifera and a GRP75 inhibitor. Withanone has multifunctional neuroprotective effects in alleviating cognitive dysfunction. In neuron-like cells, Withanone can inhibit NMDA-induced excitotoxicity. Withanone can inhibit white adipose tissue browning by blocking the formation of the GRP75-ANT2-UCP1 complex, thereby alleviating cancer-related cachexia. Withanone can be used in the research of tumors and nervous system diseases .
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Cat. No.: HY-N17756
CAS No.: 30655-48-2
Withanolide D (Compound 2) is a steroidal ester found in Withania somnifera (L.) Dunal, with anticancer activity. Withanolide D can activate the heat-shock factor 1 (HSF1)-dependent stress response. Withanolide D can be used for the research of cancer such as lymphoma .
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Cat. No.: HY-P12377
Research Areas:  

Neurological Disease

cTP-AlkF-2 is a macrocyclic peptide targeting the ganglioside GT1b receptor and can cross the blood-brain barrier. cTP-AlkF-2 induces caveolae-mediated endocytosis/transcytosis, macropinocytosis-mediated internalization, and energy-dependent active transport. cTP-AlkF-2 can serve as a delivery carrier for the synthesis of PVtCD-cTP-AlkF-2 (HY-188196). cTP-AlkF-2 can be used for research on Alzheimer's disease .
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Cat. No.: HY-N10949
CAS No.: 76938-46-0
Viscosalactone B is a withanolide found in Withania somnifera. Viscosalactone B shows potent inhibitory activities to NCI-H460, HCT-116, MCF-7 and SF-268 cancer cells with IC50 values of 0.32, 0.47, 0.4 and 0.45 μg/mL. Viscosalactone B can be used for the research of cancer .
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Cat. No.: HY-P3252AS
Pegcetacoplan- 13C3, 15N TFA is the 13C- and 15N-labeled Pegcetacoplan TFA. Pegcetacoplan is a pegylated complement C3/C3b inhibitor. Pegcetacoplan acts by specifically binding to and inhibiting C3 and C3b, thereby suppressing the complement cascade at its proximal stage. Pegcetacoplan is not a known inhibitor or inducer of CYP450 isoenzymes. Pegcetacoplan can be used for the research of complement-mediated diseases, including paroxysmal nocturnal hemoglobinuria (PNH) and age-related macular degeneration (AMD).
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