3 Results for "

X. laevis

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "X. laevis" in MCE Product Catalog:

Cat. No.: HY-121998
CAS No.: 220088-42-6
Target:  

Aurora Kinase

Research Areas:  

Others

Binucleine 2 is an isoform-specific and ATP-competitive inhibitor of Drosophila Aurora B kinase (Ki=0.36 μM), a kinase involved in cell division. It is specific for Drosophila Aurora B kinase, inhibiting it in a dose-dependent manner, with minimal inhibition of human or X. laevis Aurora B kinases at concentrations up to 100 μM. Binucleine 2 induces mitotic and cytokinesis defects in Drosophila Kc167 cells. It prevents Drosophila S2 cells from assembling a contractile ring during cell division when used at a concentration of 40 μM but does not affect ring ingression, suggesting that Aurora B kinase activity is not required for that step.
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Cat. No.: HY-P70503
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: VSIG2; V-Set And Immunoglobulin Domain Containing 2; CTXL; CTH; V-Set And Immunoglobulin Domain-Containing Protein 2; Cortical Thymocyte-Like Protein; CT-Like Protein; Cortical Thymocyte Receptor (X. laevis CTX) Like; 2210413P10Rik
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P76697
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: VSIG2; V-Set And Immunoglobulin Domain Containing 2; CTXL; CTH; V-Set And Immunoglobulin Domain-Containing Protein 2; Cortical Thymocyte-Like Protein; CT-Like Protein; Cortical Thymocyte Receptor (X. laevis CTX) Like; 2210413P10Rik
Species:  
Human
Source:  
HEK293
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