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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
XPNPEP1
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "XPNPEP1" in MCE Product Catalog:
Cat. No.: HY-RS15886
Target:
Research Areas:
XPNPEP1 Human Pre-designed siRNA Set A contains three designed siRNAs for XPNPEP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19557
Target:
Research Areas:
Xpnpep1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Xpnpep1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS26053
Target:
Research Areas:
Xpnpep1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Xpnpep1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-183739
CAS No.: 441022-67-9
Target:
Research Areas:
CQ31 is a PEPD and XPNPEP1 inhibitor, with an IC50 of 0.67 μM against PEPD and an IC50 of 122 μM against XPNPEP1. CQ31 inhibits the M24B aminopeptidase activity of PEPD and XPNPEP1. CQ31 induces the accumulation of Xaa-Pro-containing peptides, mildly inhibits DPP8/9, and triggers CASP1-dependent pyroptosis via activation of the CARD8 inflammasome and caspase-1. CQ31 can be used in research related to cancers such as acute myeloid leukemia [1] .
Cat. No.: HY-185207
CAS No.: 3034207-17-2
Target:
CQ80 is a PEPD/XPNPEP1 inhibitor and selective CARD8 inflammasome activator. CQ80 has IC50 values of 0.91 μM for PEPD, 43 μM for XPNPEP1. CQ80 promotes the accumulation of Xaa-Pro peptides by inhibiting PEPD and XPNPEP1, releases the fragment of CARD8 for inflammasome formation, and induces pyroptosis via GSDMD cleavage. CQ80 can be used for research on inflammasome, CARD8-expressing cancer cells, HIV-1-infected cell clearance, acute myeloid leukemia (AML) [1].
Cat. No.: HY-P7498
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: XPNPEP1; X-Prolyl Aminopeptidase 1; XPNPEPL1; XPNPEPL; XPNPEP; Xaa-Pro Aminopeptidase 1; X-Prolyl Aminopeptidase (Aminopeptidase P) 1; Soluble; X-Prolyl Aminopeptidase 1; Soluble; Aminoacylproline Aminopeptidase; Cytosolic Aminopeptidase P; Soluble Aminopeptidase P; X-Pro Aminopeptidase 1; X-Prolyl Aminopeptidase (Aminopeptidase P)-Like; Aminopeptidase P; Cytosolic; APP1; SAMP; SAmp
Species:
Human
Source:
E. coli
Cat. No.: HY-P700260
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: XPNPEP1; X-Prolyl Aminopeptidase 1; XPNPEPL1; XPNPEPL; XPNPEP; Xaa-Pro Aminopeptidase 1; X-Prolyl Aminopeptidase (Aminopeptidase P) 1; Soluble; X-Prolyl Aminopeptidase 1; Soluble; Aminoacylproline Aminopeptidase; Cytosolic Aminopeptidase P; Soluble Aminopeptidase P; X-Pro Aminopeptidase 1; X-Prolyl Aminopeptidase (Aminopeptidase P)-Like; Aminopeptidase P; Cytosolic; APP1; SAMP; SAmp
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
