1 Result for "

XW 17

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "XW 17" in MCE Product Catalog:

Cat. No.: HY-183548
Target:  

PARP

Research Areas:  

Inflammation/Immunology

XW-17 is a PARP14 inhibitor with an IC50 of 3.03 nM and selectivity over other PARP family members.XW-17 suppresses PARP14-mediated mono-ADP-ribosylation, engages and stabilizes endogenous PARP14 protein.XW-17 attenuates skin lesions and decreases expression of IL-4, IL-13, IgE, and IL-17A in an atopic dermatitis-like mouse model.XW-17 can be used for the research of atopic dermatitis .
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