5 Results for "

YAP-TEAD binding

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "YAP-TEAD binding" in MCE Product Catalog:

27
27 Publications Verification
Cat. No.: HY-B0990
CAS No.: 1393-48-2
Thiostrepton is a thiazole antibiotic which selectively inhibits FOXM1. FOXM1 binds to YAP/TEAD complex. YAP/TEAD/FOXM1 complex binding at regulatory regions of genes governing cell cycle may impact cell proliferation .
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2
2 Cited Publications
Cat. No.: HY-P2244A
CAS No.: 1659305-79-9
Target:  

YAP

Research Areas:  

Cancer

YAP-TEAD-IN-1 TFA is a potent and competitive peptide inhibitor of YAP-TEAD interaction (IC50=25 nM). YAP-TEAD-IN-1 TFA is a 17mer peptide and shows a higher the binding affinity to TEAD1 (Kd=15 nM) than YAP (50-171) (Kd= 40 nM) .
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2
2 Cited Publications
Cat. No.: HY-P2244
CAS No.: 1659305-78-8
Target:  

YAP

Research Areas:  

Cancer

YAP-TEAD-IN-1 is a potent and competitive inhibitor of?YAP–TEAD interaction (IC50=25 nM). YAP-TEAD-IN-1 is a 17mer peptide and shows a higher the binding affinity to TEAD1 (Kd=15 nM) than YAP (50-171) (Kd=40 nM) .
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Cat. No.: HY-161443
Target:  

YAP

Research Areas:  

Cancer

TEAD-IN-9 (compound 17) is a TEAD1 inhibitor with an IC50 of 0.29 μM. TEAD-IN-9 targets the palmitoyl pocket of TEAD, thereby effectively inhibiting the binding of YAP-TEAD and blocking the transcriptional function of YAP-TEAD .
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Cat. No.: HY-179706
CAS No.: 2576427-49-9
Target:  

YAP

Research Areas:  

Cancer

VS3 is a YAP-TEAD interaction inhibitor. VS3 directly disrupts the interaction between YAP-TEAD by binding to TEAD4 Interface 3 (Kd = 6 μM) on the surface. VS3 exhibits anti-proliferative activity against HT29, HCT116, and A2780. VS3 can be used for research on colorectal adenocarcinoma and ovarian cancer .
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