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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
YL633
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "YL633" in MCE Product Catalog:
Cat. No.: HY-189839
CAS No.: 3100239-28-6
YL633 is a selective CRBN-recruiting HDAC8 PROTAC degrader with DC50 = 3.3 nM. YL633 binds to the CRBN E3 ubiquitin ligase and mediates HDAC8 degradation. YL633 inhibits HDAC3 enzymatic activity with IC50 of 342.9 nM, and induces degradation of HDAC6 and HDAC7. YL633 inhibits DLBCL cell proliferation. YL633 can be used in research related to diffuse large B-cell lymphoma .
Cat. No.: HY-189873
Research Areas:
HDAC8 ligand 4 is an HDAC8 ligand. HDAC8 ligand 4 can be used as a target protein ligand to synthesize HDAC8 PROTAC degraders, such as YL633 (HY-189839). HDAC8 ligand 4 can be used in research related to diffuse large B-cell lymphoma .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
