1 Result for "

YW1128

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "YW1128" in MCE Product Catalog:

Cat. No.: HY-133180
CAS No.: 2131223-64-6
Purity:  99.38%
Target:  

Wnt β-catenin

Research Areas:  

Metabolic Disease

YW1128 (compound 3a) is a potent Wnt/β-Catenin inhibitor. YW1128 induces the proteasome degradation of β-catenin and subsequent inhibits the Wnt/β-catenin signaling in cells. YW1128 significantly decreases hepatic lipid accumulation. YW1128 improves glucose tolerance of high fat diet-fed mice without noticeable toxicity. YW1128 down regulates the genes involved in the glucose and fatty acid anabolism .
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