Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
ZEB1
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "ZEB1" in MCE Product Catalog:
30
1
1 Cited Publications
Cat. No.: HY-W011338
CAS No.: 85-68-7
Research Areas:
Benzyl butyl phthalate, a member of phthalic acid esters (PAEs), can trigger the migration and invasion of hemangioma (HA) cells via upregulation of Zeb1. Benzyl butyl phthalate activates aryl hydrocarbon receptor (AhR) in breast cancer cells to stimulate SPHK1/S1P/S1PR3 signaling and enhances formation of metastasis-initiating breast cancer stem cells (BCSCs) [1] .
1
1 Cited Publications
Cat. No.: HY-RS16025
Target:
Research Areas:
ZEB1 Human Pre-designed siRNA Set A contains three designed siRNAs for ZEB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
1
Cat. No.: HY-W011338S
CAS No.: 93951-88-3
Cat. No.: HY-RS16881
Target:
Research Areas:
Zeb1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Zeb1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23323
Target:
Research Areas:
Zeb1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Zeb1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-W011338R
CAS No.: 85-68-7
Research Areas:
Benzyl butyl phthalate (Standard) is the analytical standard of Benzyl butyl phthalate. This product is intended for research and analytical applications. Benzyl butyl phthalate, a member of phthalic acid esters (PAEs), can trigger the migration and invasion of hemangioma (HA) cells via upregulation of Zeb1. Benzyl butyl phthalate activates aryl hydrocarbon receptor (AhR) in breast cancer cells to stimulate SPHK1/S1P/S1PR3 signaling and enhances formation of metastasis-initiating breast cancer stem cells (BCSCs) [1] .
Cat. No.: HY-N9921
CAS No.: 163597-24-8
Category:
Cat. No.: HY-189737
Target:
Research Areas:
Anticancer agent-367 is a 3-hydroxy-3′,4′,5′-trimethoxyflavone derivative with selective cytotoxicity against osteosarcoma cells (IC50 = 14 μM). Anticancer agent-367 reduces AKT phosphorylation levels in 143B osteosarcoma cells and downregulates the expression of epithelial-mesenchymal transition-related genes such as ZEB1, MMP2, and MMP9. The combination of Anticancer agent-367 with Doxorubicin (HY-15142A) produces a synergistic antiproliferative effect on 143B cells. Anticancer agent-367 can be used in osteosarcoma-related research [1].
Cat. No.: HY-183629
Target:
Research Areas:
ZNF281-IN-1 is a ZNF281 inhibitor. ZNF281-IN-1 disrupts the binding of transcriptionally active DNA-bound ZNF281 to the promoters of target genes including TRIM35 and ZEB1. ZNF281-IN-1 inhibits tumor cell proliferation, stabilizes P53 and upregulates PUMA to induce apoptosis, while triggering cellular senescence. ZNF281-IN-1 completely prevents Doxorubicin (HY-15142A)-induced cardiotoxicity (AIC), and enhances rather than impairs the antitumor efficacy of Doxorubicin. ZNF281-IN-1 completely blocks the distant metastasis of melanoma to the lungs. ZNF281-IN-1 can be used in the research of cardiotoxicity, lung cancer and metastatic melanoma [1].
Cat. No.: HY-P87268
Synonyms: AREB 6 antibody; AREB6 antibody; BZP antibody; Delta crystallin enhancer binding factor 1 antibody; DELTA EF1 antibody; FECD6 antibody; MGC133261 antibody; Negative regulator of IL 2 antibody; Negative regulator of IL2 antibody; NIL 2 A antibody
Cat. No.: HY-189570
CAS No.: 3127781-85-2
TMLB-G9 is an orally active B3GAT3 inhibitor (human Kd = 0.72 μM). TMLB-G9 blocks glycosaminoglycan biosynthesis and inhibits chondroitin sulfate biosynthesis in hepatocellular carcinoma cells. TMLB-G9 induces apoptosis by upregulating cleaved PARP and cleaved caspase-3. TMLB-G9 induces G0/G1 cell cycle arrest by upregulating Rb and downregulating CDK1, CDK2, Cyclin A2, Cyclin E1, and phosphorylated Rb. TMLB-G9 inhibits migration and invasion by reversing epithelial-mesenchymal transition, manifested as upregulation of E-cadherin and downregulation of N-cadherin, vimentin, MMP-2, MMP-9, and ZEB1. TMLB-G9 inhibits colony formation. TMLB-G9 exhibits broad-spectrum antitumor activity against multiple cancer cell lines. TMLB-G9 can be used for research on hepatocellular carcinoma [1].
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
