12 Results for "

acarbose

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "acarbose" in MCE Product Catalog:

15
15 Cited Publications
Cat. No.: HY-B0089
CAS No.: 56180-94-0
Synonyms: BAY g 5421
Acarbose (BAY g 5421), antihyperglycemic agent, is an orally active alpha-glucosidase inhibitor (IC50=11 nM). Acarbose can potentiate the hypoglycemic effects of sulfonylureas or insulin .
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Cat. No.: HY-B0089R
CAS No.: 56180-94-0
Synonyms: BAY g 5421 (Standard)
Acarbose (Standard) is the analytical standard of Acarbose. This product is intended for research and analytical applications. Acarbose (BAY g 5421), antihyperglycemic agent, is an orally active alpha-glucosidase inhibitor (IC50=11 nM). Acarbose can potentiate the hypoglycemic effects of sulfonylureas or insulin .
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Cat. No.: HY-B0089S
CAS No.: 1260619-60-0
Synonyms: BAY g 5421-d4
Acarbose-d4 (BAY g 5421-d4) is deuterium labeled Acarbose. Acarbose (BAY g 5421), antihyperglycemic agent, is an orally active alpha-glucosidase inhibitor (IC50=11 nM). Acarbose can potentiate the hypoglycemic effects of sulfonylureas or insulin .
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Cat. No.: HY-B0089A
CAS No.: 1221158-13-9
Synonyms: Bay-g 5421 sulfate
Acarbose (BAY g 5421) sulfate, antihyperglycemic agent, is an orally active alpha-glucosidase inhibitor (IC50=11 nM). Acarbose sulfate can potentiate the hypoglycemic effects of sulfonylureas or insulin .
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Cat. No.: HY-131504A
CAS No.: 38231-86-6
Target:  

Glycosidase

Research Areas:  

Metabolic Disease

Valienamine is the alpha-glucosidase inhibitor. Valienamine is the key functional component of many natural glycosidase inhibitors including the crop protectant validamycin A and the antidiabetic agent acarbose .
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Cat. No.: HY-E72048
Research Areas:  

Others

Acarbose 7IV-phosphotransferase (EC 2.7.1.187) is a transferase that can convert acarbose and ATP into acarbose 7(IV)-phosphate, ADP and H +.
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Cat. No.: HY-168462
Target:  

Glycosidase

Research Areas:  

Metabolic Disease

α-Glucosidase-IN-82 (compound 8l) is a potent inhibitor of α-Glucosidase, with the IC50 of 13.66 μM. α-Glucosidase-IN-82 exhibits a 52-fold increase in inhibitory activity relative to Acarbose (HY-B0089) .
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Cat. No.: HY-170606
CAS No.: 3068686-30-3
Target:  

Glycosidase

Research Areas:  

Metabolic Disease

α-Glucosidase-IN-79 (Compound 4d9) is a non-competitive α-Glucosidase inhibitor with an IC50 of 2.11 μM, which is more potent than existing α-Glucosidase inhibitors such as Acarbose (HY-B0089) (IC50 of 327.0 μM) and HXH8r (IC50 of 15.32 μM). α-Glucosidase-IN-79 is non-cytotoxic to human normal hepatocyte (LO2) cells and shows good metabolic stability in rat plasma. α-Glucosidase-IN-79 holds promise for research into type 2 diabetes .
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Cat. No.: HY-176221
Target:  

Glycosidase

Research Areas:  

Metabolic Disease

α-Glucosidase-IN-92 (compound 14b) is a non-competitive inhibitor targeting α-glucosidase (IC50=64.0 μM), with better inhibitory potency than Acarbose (HY-B0089) (IC50=750 μM). α-Glucosidase-IN-92 has good oral bioavailability and can cross the blood-brain barrier. α-Glucosidase-IN-92 can delay carbohydrate hydrolysis and reduce postprandial blood glucose. α-Glucosidase-IN-92 can be used in anti-glycemic research for type 2 diabetes .
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Cat. No.: HY-E71525
Research Areas:  

Others

2-epi-5-epi-Valiolone 7-kinase (EC 2.7.1.188) is involved in the biosynthesis of the oligosaccharide acarbose.
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Cat. No.: HY-E71526
Research Areas:  

Others

2-epi-5-epi-Valiolone 7-phosphate 2-epimerase (EC 5.1.3.35) is involved in the biosynthesis of the α-glucosidase inhibitor acarbose.
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Cat. No.: HY-178170
Target:  

Amylases Glycosidase

Research Areas:  

Metabolic Disease

α-Amylase/α-Glucosidase-IN-22 is an inhibitor of α-Amylase and α-Glucosidase with IC50 values of 1.71 and 10.36 nM (5 and 23.8 folds more potent than Acarbose (HY-B0089)). α-Amylase/α-Glucosidase-IN-22 can be used for the researches of metabolic disease, such as diabetes .
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