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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
54 Results for "
adipose cell
" in MedChemExpress (MCE) Product Catalog:
Products (54)
54 Results for "adipose cell" in MCE Product Catalog:
13
13 Publications Verification
Synonyms: 2-Phospho-L-ascorbic acid magnesium; LAA2P magnesium
13
13 Publications Verification
Synonyms: 2-Phospho-L-ascorbic acid trisodium
13
13 Publications Verification
Synonyms: 2-Phospho-L-ascorbic acid; LAA2P
13
13 Publications Verification
Synonyms: 2-Phospho-L-ascorbic acid magnesium hydrate; LAA2P magnesium hydrate
7
5
5 Cited Publications
Cat. No.: HY-N2593
CAS No.: 32507-66-7
4
4 Cited Publications
Cat. No.: HY-N0898A
CAS No.: 18829-70-4
Synonyms: (-)-Cianidanol; (-)-Catechuic acid
Category:
Plant Flavonoids Flavanols Phenols Polyphenols Other Families Extract Disease Research Fields Cancer
Target:
2
1
1
1 Cited Publications
Synonyms: E1(Standard); Oestrone (Standard)
1
1
1 Cited Publications
Target:
1
1 Cited Publications
Synonyms: trans-10,cis-12 CLA2
Research Areas:
(10E,12Z)-Octadeca-10,12-dienoic acid (trans-10,cis-12 CLA2) is an orally active PPARα activator and inhibits adipocyte differentiation. (10E,12Z)-Octadeca-10,12-dienoic acid and its downstream metabolites have various antioxidant and antitumor activities. (10E,12Z)-Octadeca-10,12-dienoic acid can induce proinflammatory cytokines and chemokines, which would lead to decreased adipogenesis and insulin resistance in adipose tissue. (10E,12Z)-Octadeca-10,12-dienoic acid can affect many aspects of milk fat synthesis. (10E,12Z)-Octadeca-10,12-dienoic acid reduces expression of lipogenic enzymes and inhibits the desaturation of fatty acids. (10E,12Z)-Octadeca-10,12-dienoic acid can reduce lipoprotein lipase (LPL) activity in cultured 3T3-L1 adipocytes and enhance triacylglycerol release from these cells. (10E,12Z)-Octadeca-10,12-dienoic acid decreases the expression of hepatic stearoyl-CoA desatyrase mRNA in mice. (10E,12Z)-Octadeca-10,12-dienoic acid is associated with changes in mucosal NF-κB and Cyclin D1 protein levels in mice .
Cat. No.: HY-P10735
CAS No.: 181591-59-3
Synonyms: Gastric inhibitory polypeptide(mouse); GIP(1-42) (mouse)
Research Areas:
Cat. No.: HY-116003
CAS No.: 263399-35-5
Target:
Cat. No.: HY-B0234S2
CAS No.: 53866-34-5
Synonyms: E1-d4; Oestrone-d4
Cat. No.: HY-P991736
Target:
Research Areas:
Cat. No.: HY-116330
CAS No.: 11079-53-1
Category:
Plant Hyperlcurn perforatum L. Extract Anti-inflammation/Immunoregulatory Antibiotics Guttiferae Extract Disease Research Anticancer
Target:
Triphenyl phosphate is an orally active, blood-brain barrier-permeable aryl organophosphate flame retardant and endocrine disruptor. Triphenyl phosphate disrupts mitochondrial dynamic balance through oxidative stress, induces excessive mitophagy and apoptosis, and ultimately leads to myocardial fibrosis. In the brain, Triphenyl phosphate activates the NF-κB inflammatory pathway by disrupting the gut microbiota, alters tryptophan metabolism and elevates neurotoxins, thereby inducing anxiety- and depression-like behaviors. In the skeletal and reproductive systems, Triphenyl phosphate inhibits osteoblast differentiation and induces germ cell apoptosis by suppressing the MAPK/ERK pathway and activating the JNK signal, respectively. In adipose and placental tissues, Triphenyl phosphate promotes lipid accumulation by activating the PI3K/AKT-PPARγ axis, and disrupts placental metabolism via the MAOA/ROS/NF-κB cascade, impairing neurodevelopment of offspring .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
