42

5-Ethynyl-2'-deoxyuridine

42 Publications Verification

Cat. No.: HY-118411

CAS No.: 61135-33-9

Purity: 99.78%

Synonyms: EdU

Target:

PROTAC Linkers

Research Areas:

Cancer

5-Ethynyl-2'-deoxyuridine (EdU), a thymidine analogue, is incorporated into cellular DNA during DNA replication and the subsequent reaction of EdU with a fluorescent azide in a “Click” reaction. EdU staining is a fast, sensitive and reproducible method to study cell proliferation . 5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . 5-Ethynyl-2'-deoxyuridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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26

TGN-020

26 Cited Publications

Cat. No.: HY-W008574

CAS No.: 51987-99-6

Target:

PROTAC Linkers

Research Areas:

Inflammation/Immunology Cancer

TGN-020 is a selective Aquaporin 4 (AQP4) inhibitor with an IC₅₀ of 3.1 μM . TGN-020 is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .TGN-020 alleviates edema and inhibits glial scar formation after spinal cord compression injury in rats .

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26

TGN-020 sodium

26 Cited Publications

Cat. No.: HY-W008574A

CAS No.: 1313731-99-5

Target:

PROTAC Linkers

Research Areas:

Inflammation/Immunology Cancer

TGN-020 sodium is a selective Aquaporin 4 (AQP4) inhibitor with an IC₅₀ of 3.1 μM . TGN-020 sodium is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . TGN-020 sodium alleviates edema and inhibits glial scar formation after spinal cord compression injury in rats .

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9

EGNHS

9 Cited Publications

Cat. No.: HY-130458

CAS No.: 70539-42-3

Purity: 97.45%

Synonyms: EGS crosslinker

Target:

PROTAC Linkers

Research Areas:

Cancer

EGNHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .

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9

Leukotriene B4

9 Cited Publications

Cat. No.: HY-107608

CAS No.: 71160-24-2

Purity: ≥98.0%

Synonyms: LTB4; 5(S),12(R)-DiHETE

Category:

Microorganisms Ketones, Aldehydes, Acids Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields Inflammation/Immunology Cardiovascular System Disorder

Target:

Endogenous Metabolite PROTAC Linkers Leukotriene Receptor

Leukotriene B4 (LTB4) is known as one of the most potent chemoattractants and activators of leukocytes and is involved in inflammatory diseases. Leukotriene B4 is also an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .

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7

Tyloxapol

7 Cited Publications

Cat. No.: HY-B1068

CAS No.: 25301-02-4

Target:

Biochemical Assay Reagents

Research Areas:

Metabolic Disease

Tyloxapol is a nonionic liquid polymer of the alkyl aryl polyether alcohol type, used as a surface active stabilizer. Tyloxapol is used to induce hyperlipidemia in animals .

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