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25 Results for "

amazonensis

" in MedChemExpress (MCE) Product Catalog:

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PK 11195

9 Cited Publications

Cat. No.: HY-19567

CAS No.: 85532-75-8

Synonyms: RP 52028

Target:

Parasite

Research Areas:

Infection

PK 11195 (RP 52028) is a ligand of translocator protein (TSPO), which targets Leishmania chemotherapy, with IC₅₀s of 14.2 μM, 8.2 μM, 3.5 μM for L. amazonensis, L. major and L. braziliensis, respectively.

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Zolunicant

Cat. No.: HY-147428

CAS No.: 188125-42-0

Purity: 99.29%

Synonyms: MM-110; (±)-18-Methoxycoronaridine

Target:

nAChR Parasite

Research Areas:

Infection Neurological Disease

Zolunicant (MM-110) is a potent inhibitor against nicotinic α3β4 receptors with an IC₅₀ of 0.90 μM to combat addiction. Zolunicant can decrease the self-administration of several addictive agents including morphine, methamphetamine, nicotine, and ethanol in rat model. Zolunicant can be studied as a potential research for multiple forms of agent abuse . Zolunicant also reveals a potent leishmanicide effect against Leishmania amazonensis .

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4-(Bromomethyl)benzoic acid

Cat. No.: HY-21496

CAS No.: 6232-88-8

Synonyms: 4-Carboxybenzyl bromide

Target:

Parasite

Research Areas:

Infection

4-(Bromomethyl)benzoic acid (4-Carboxybenzyl bromide) is an antiparasitic agent with low activity against Leishmania amazonensis and Trypanosoma cruzi. 4-(Bromomethyl)benzoic acid has certain cytotoxicity to PBMCs, with an IC₅₀ of 88.8 μM .

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Aluminum phthalocyanine chloride

Cat. No.: HY-129959

CAS No.: 14154-42-8

Synonyms: AlClPc

Aluminum phthalocyanine chloride is a photosensitizer that effectively inhibits the parasite Leishmania amazonensis (the causative agent of cutaneous leishmaniasis) by light-mediated cytolysis. Aluminum phthalocyanine chloride causes parasite morphology and cytolysis of isolated amasilians, while higher photosensitizer concentrations and light intensities are required to induce lysis of mammalian cells. Aluminum phthalocyanine chloride lyses parasites within infected J774 macrophages and can be used to further investigate the study of leishmaniasis .

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