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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
30 Results for "
ankylosing
" in MedChemExpress (MCE) Product Catalog:
Products (30)
30 Results for "ankylosing" in MCE Product Catalog:
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Phenylbutazone is an efficient reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS). Phenylbutazone, a hepatotoxin, is a nonsteroidal anti-inflammatory agent (NSAID). Phenylbutazone induces muscle blind-like protein 1 (MBNL1) expression and has the potential for ankylosing spondylitis research .
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2 Cited Publications
Cat. No.: HY-B0634
CAS No.: 89796-99-6
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Aceclofenac is an orally active nonsteroidal anti-inflammatory agent (NSAID), with analgesic and anti-inflammatory properties. Aceclofenac is used for the research of osteoarthritis, ankylosing spondylitis, rheumatoid arthritis .
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Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Inflammation/Immunology
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Cat. No.: HY-153780
CAS No.: 2467732-66-5
Synonyms: DC-806; LY4100504; S-011806
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Navepdekinra (DC-806) is an orally active, potent interleukin-17A (IL-17A) inhibitor (IC50 = 10.81 nM). Navepdekinra disrupts the IL-17A protein-receptor interaction, suppressing the downstream pro-inflammatory signaling pathway. Navepdekinra inhibits arthritis in a collage-induced arthritis (CIA) rat model. Navepdekinra can be used for psoriasis, psoriatic arthritis, and ankylosing spondylitis .
Cat. No.: HY-P99754
CAS No.: 1796570-08-5
Synonyms: BCD-085
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Cat. No.: HY-W009706
CAS No.: 22131-79-9
Synonyms: Allopydin; W-7320
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Alclofenac (Allopydin) is an orally active prostaglandin synthase inhibitor with anti-inflammatory, analgesic and antipyretic activities. Alclofenac irreversibly inhibits platelet aggregation. Alclofenac can be used in research related to rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, low back pain and sciatica .
Cat. No.: HY-P99335
CAS No.: 1792181-33-9
Synonyms: Anti-Human IL17A Recombinant Antibody; SHR-1314
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Cat. No.: HY-P99652
CAS No.: 2428381-52-4
Synonyms: AK 111
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Cat. No.: HY-N7700
CAS No.: 15769-56-9
Synonyms: G2013
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Guluronic acid (G2013) is an orally active oxidative stress regulator and anti-inflammatory agent that exerts pharmacological effects by down-regulating various pro-inflammatory and oxidative stress-related genes (such as TLR4, NF-κB, iNOS, etc.) and inhibiting the activities of COX-2, MMPs and VEGF. Low-dose Guluronic acid up-regulates the expression of immunoregulatory genes SHIP1 and SOCS1, thereby effectively inhibiting cancer-related inflammation, tumor angiogenesis, cell adhesion and metastasis, while reducing the accumulation of immunosuppressive cells. Guluronic acid significantly prolongs the survival time of tumor-bearing hosts within a concentration range without direct cytotoxicity, demonstrating favorable safety. Guluronic acid has involved in the research of multiple sclerosis, ankylosing spondylitis, breast cancer and other inflammatory diseases .
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B3GNT2-IN-1 is a β-1,3-N-acetylglucosaminyltransferase 2 (B3GNT2) inhibitor with an IC50 of 0.009 μM. B3GNT2-IN-1 is applicable to research related to rheumatoid arthritis, ankylosing spondylitis and psoriasis .
Synonyms: (R)-ABBV-105
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(R)-Elsubrutinib ((R)-ABBV-105) is a Btk inhibitor. (R)-Elsubrutinib can be used in studies of immune diseases (such as rheumatoid arthritis, psoriasis, ankylosing spondylitis, asthma, systemic lupus erythematosus) and cancer .
Cat. No.: HY-B0230S
CAS No.: 1219794-69-0
Cat. No.: HY-P991682
CAS No.: 3037572-57-6
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Emzotamig is a bispecific antibody targeting TNFRSF17 and NCR1. Emzotamig is promising for research of autoimmune diseases associated with TNF overexpression, such as rheumatoid arthritis and ankylosing spondylitis .
Cat. No.: HY-B0230S2
CAS No.: 1325559-13-4
Cat. No.: HY-127150
CAS No.: 17449-96-6
Synonyms: Perclusone
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Clofezone (Perclusone) is an antirheumatic agent that inhibits collagen formation in rat Chondrus granulomas. Clofezone can be used in the study of various rheumatic diseases, especially arthritis (RA) and ankylosing spondylitis (AS) .
Cat. No.: HY-158159
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IL17A-IN-1 (compound 72) is an orally active Interleukin 17A inhibitor. IL17A-IN-1 can be used in the study of inflammatory and autoimmune diseases (plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis, etc.), as well as cancer .
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Phenylbutazone (Standard) is the analytical standard of Phenylbutazone. This product is intended for research and analytical applications. Phenylbutazone is an efficient reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS). Phenylbutazone, a hepatotoxin, is a nonsteroidal anti-inflammatory agent (NSAID). Phenylbutazone induces muscle blind-like protein 1 (MBNL1) expression and has the potential for ankylosing spondylitis research .
Cat. No.: HY-12385
CAS No.: 56187-89-4
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Ximoprofen is a propionic nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory property. Ximoprofen can be used for ankylosing spondylitis research .
Cat. No.: HY-B0634S
CAS No.: 2748492-20-6
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
