3 Results for "

antedrug

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "antedrug" in MCE Product Catalog:

Cat. No.: HY-110207
CAS No.: 677773-91-0
Purity:  98.52%
Research Areas:  

Inflammation/Immunology

SM-324405 is a TLR7 agonistic antedrug (EC50 = 50 nM), with pEC50 values of 7.3 and 6.6 for human TLR7 and Rat TLR7, respectively. SM-324405 is used for immunoresearch of allergic diseases. An antedrug is defined as a locally active compound that is designed to be rapidly metabolized to an inactive form upon entry into the circulation and prevents systemic toxicity by losing its agonistic activity in a plasmatic environment .
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Cat. No.: HY-106983
CAS No.: 192057-17-3
Research Areas:  

Inflammation/Immunology

GR 250495X is an inhaled glucocorticoid receptor agonist. GR 250495X is designed as a antedrug, which takes effect locally in the lungs but is rapidly metabolized and inactivated in the bloodstream after entering the systemic circulation, thereby minimizing systemic side effects. GR 250495X can be used in asthma research .
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Cat. No.: HY-110207R
CAS No.: 677773-91-0
SM-324405 (Standard) is the analytical standard of SM-324405 (HY-110207). This product is intended for research and analytical applications. SM-324405 is a TLR7 agonistic antedrug (EC50 = 50 nM), with pEC50 values of 7.3 and 6.6 for human TLR7 and Rat TLR7, respectively. SM-324405 is used for immunoresearch of allergic diseases. An antedrug is defined as a locally active compound that is designed to be rapidly metabolized to an inactive form upon entry into the circulation and prevents systemic toxicity by losing its agonistic activity in a plasmatic environment .
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