37 Results for "

antidiabetic effect

" in MedChemExpress (MCE) Product Catalog:
Products (37)

37 Results for "antidiabetic effect" in MCE Product Catalog:

3
Marein
Marein
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3 Cited Publications
Cat. No.: HY-N7676
CAS No.: 535-96-6
Category:  

Cardiovascular Disease Flavonoids Chalcones Neurological Disease Phenols Polyphenols Plants Other Families Extract Disease Research Fields

Target:  

AMPK HDAC

Marein has the neuroprotective effect due to a reduction of damage to mitochondria function and activation of the AMPK signal pathway. Marein improves insulin resistance induced by high glucose in HepG2 cells through CaMKK/AMPK/GLUT1 to promote glucose uptake, through IRS/Akt/GSK-3β to increase glycogen synthesis, and through Akt/FoxO1 to decrease gluconeogenesis. Marein is a HDAC inhibitor with an IC50 of 100 μM. Marein has beneficial antioxidative, antihypertensive, antihyperlipidemic and antidiabetic effects .
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2
Amarogentin
Amarogentin
0 Images
2 Cited Publications
Cat. No.: HY-N2447
CAS No.: 21018-84-8
Category:  

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