60 Results for "

antidotes

" in MedChemExpress (MCE) Product Catalog:
Products (60)

60 Results for "antidotes" in MCE Product Catalog:

51
Deferiprone
Deferiprone
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51 Publications Verification
Cat. No.: HY-B0568
CAS No.: 30652-11-0
Target:  

Ferroptosis HCV Apoptosis COX Histone Demethylase

Research Areas:  

Cardiovascular Disease Infection Neurological Disease Cancer

Deferiprone is a potent, orally active, brain-penetrant, cell-penetrant, skin-permeable, free iron chelating agent. Deferiprone inhibits the proliferation and migration, and stimulates apoptosis in tumor cell. Deferiprone can inhibit KDM. Deferiprone has antianemic, neuroprotective, anti-inflammatory, antioxidant, and antidotal activity. Deferiprone can be used in cancer, cardiovascular disease, infection, inflammation, and neurological disease study .
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12
L-Methionine
L-Methionine
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12 Cited Publications
Cat. No.: HY-N0326
CAS No.: 63-68-3
Category:  

Anti-aging Endocrine diseases Amino acids Endogenous metabolite Research on Agricultural Breeding Agricultural Research Microorganisms Other Diseases Disease markers Nervous System Disorder Disease Research Fields Cardiovascular System Disorder

Target:  

Environmental Pollutants Endogenous Metabolite Apoptosis Keap1-Nrf2

L-Methionine is an L-isomer of orally active Methionine, an essential amino acid. Methionine is a strong liver antidote that acts as a liver protector. L-Methionine can inhibit cell proliferation and induce cell apoptosis. L-Methionine has antitumor and antioxidant activity .
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12
AGN 193109
AGN 193109
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12 Cited Publications
Cat. No.: HY-U00449
CAS No.: 171746-21-7
Target:  

RAR/RXR

Research Areas:  

Cancer

AGN 193109 is a retinoid analog, and acts as a specific and highly effective antagonist of retinoic acid receptors (RARs), with Kds of 2 nM, 2 nM, and 3 nM for RARα, RARβ, and RARγ, respectively. AGN 193109 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. AGN 193109 is the antidote for retinoic acidosis, that ameliorates the skin and mucosal toxicity.
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5
Fomepizole
Fomepizole
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5 Cited Publications
Cat. No.: HY-B0876
CAS No.: 7554-65-6
Synonyms: 4-Methylpyrazole
Target:  

Cytochrome P450

Research Areas:  

Metabolic Disease

Fomepizole (4-Methylpyrazole) is a potent cytochrome P450 (CYP2E1) inhibitor. Fomepizole is a competitive inhibitor of the enzyme alcohol dehydrogenase. Fomepizole blocks further conversion of methanol and ethylene glycol to toxic metabolites. Fomepizole has the potential for an antidote for ethylene glycol or methanol poisoning .
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5
Fomepizole hydrochloride
Fomepizole hydrochloride
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5 Cited Publications
Cat. No.: HY-B0876A
CAS No.: 56010-88-9
Synonyms: 4-Methylpyrazole hydrochloride
Target:  

Cytochrome P450

Research Areas:  

Metabolic Disease

Fomepizole (4-Methylpyrazole) hydrochloride is a potent and orally active cytochrome P450 (CYP2E1) inhibitor. Fomepizole hydrochloride is a competitive inhibitor of the enzyme alcohol dehydrogenase. Fomepizole hydrochloride blocks further conversion of methanol and ethylene glycol to toxic metabolites. Fomepizole hydrochloride has the potential for an antidote for ethylene glycol or methanol poisoning .
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3
Hydroxocobalamin
Hydroxocobalamin
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3 Cited Publications
Cat. No.: HY-B2209
CAS No.: 13422-51-0
Synonyms: Vitamin B12a
Category:  

Natural Products Metabolic Disease Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

Hydroxocobalamin (Vitamin B12a) is a cyanide antidote. Hydroxocobalamin can decrease the cell and plasma cyanide concentrations and increase survival rate in acute cyanide poisoning. Hydroxocobalamin can improve newborn Cbl-C defect-induced metabolic profile and neurocognitive outcome. Hydroxocobalamin can normalize Vitamin B12 deficiency. Hydroxocobalamin can induce acute kidney injury. Hydroxocobalamin can be used for the researches of metabolic and neurological disease .
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3
Pralidoxime chloride
Pralidoxime chloride
0 Images
3 Cited Publications
Cat. No.: HY-B1200
CAS No.: 51-15-0
Synonyms: 2-PAM chloride
Target:  

Cholinesterase (ChE)

Research Areas:  

Neurological Disease

Pralidoxime chloride is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime chloride reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime chloride is an antidote for organophosphate poisoning .
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2
Physostigmine
Physostigmine
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2 Cited Publications
Cat. No.: HY-N6608
CAS No.: 57-47-6
Synonyms: Eserine
Category:  

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