36

Trolox

36 Publications Verification

Cat. No.: HY-101445

CAS No.: 53188-07-1

Purity: 99.87%

Target:

Reactive Oxygen Species (ROS) Ferroptosis Apoptosis

Research Areas:

Cancer

Trolox is an analogue of vitamin E with a powerful antioxidant effect. Trolox is also a powerful inhibitor of membrane damage .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

17

Montelukast sodium

17 Cited Publications

Cat. No.: HY-13315

CAS No.: 151767-02-1

Purity: 99.84%

Synonyms: MK0476

Target:

Leukotriene Receptor

Research Areas:

Inflammation/Immunology Cancer

Montelukast sodium (MK0476) is a potent, selective and orally active antagonist of cysteinyl leukotriene receptor 1 (CysLT₁). Montelukast sodium can be used for the reseach of asthma and liver injury. Montelukast sodium also has an antioxidant effect in intestinal ischemia-reperfusion injury, and could reduce cardiac damage. Montelukast sodium decreases eosinophil infiltration into the asthmatic airways. Montelukast sodium can also be used for COVID-19 research .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

17

Montelukast

17 Cited Publications

Cat. No.: HY-13315A

CAS No.: 158966-92-8

Purity: 99.94%

Synonyms: MK0476 free base

Target:

Leukotriene Receptor

Research Areas:

Inflammation/Immunology Cancer

Montelukast (MK0476 free base) is a potent, selective and orally active antagonist of cysteinyl leukotriene receptor 1 (CysLT₁). Montelukast can be used for the reseach of asthma and liver injury. Montelukast also has an antioxidant effect in intestinal ischemia-reperfusion injury, and could reduce cardiac damage. Montelukast decreases eosinophil infiltration into the asthmatic airways. Montelukast can also be used for COVID-19 research .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

12

Higenamine

12 Cited Publications

Cat. No.: HY-N2037

CAS No.: 5843-65-2

Synonyms: Norcoclaurine; Demethyl-Coclaurine

Category:

Alkaloids Phenols Polyphenols Plants Aconitum carmichaeli Debx. Extract Disease Research Fields Isoquinoline Alkaloids Endocrinology Ranunculaceae Extract

Target:

MAP3K MDM-2/p53 Adrenergic Receptor ROS Kinase Apoptosis

Higenamine (Norcoclaurine), a β2-AR agonist with antioxidant capability, is a key component of the Chinese herb aconite root that prescribes for treating symptoms of heart failure in the oriental Asian countries. Higenamine is also a α1-adrenergic receptor antagonist with hypotensive effect. is a selective LSD1 inhibitor (IC₅₀=1.47 μM) that can be isolated from aconite. Higenamine hydrochloride has anti-inflammatory and antibacterial activity. Higenamine protects myocyte Apoptosis and ischemia/reperfusion (I/R) injury through selective activation of beta2-adrenergic receptor (β2-AR). Higenamine also reduces I/R-induced myocardial infarction in mice. Higenamine can attenuate IL-1β-induced Apoptosis through ROS-mediated PI3K/Akt signaling pathway. Higenamine protects brain cells from oxygen deprivation. Higenamine can promote bone formation in osteoporosis through the SMAD2/3 pathway. Higenamine can be used to study cancer, inflammation, cardiorenal syndrome and other diseases .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

11

Idebenone

11 Cited Publications

Cat. No.: HY-N0303

CAS No.: 58186-27-9

Target:

Mitochondrial Metabolism Apoptosis

Research Areas:

Neurological Disease

Idebenone, a well-appreciated mitochondrial protectant, exhibits protective efficacy against neurotoxicity and can be used for the research of Alzheimer's disease, Huntington's disease. Idebenone (oxidised form) has a dose-dependent inhibitory effect on the enzymatic metabolism of arachidonic acid in astroglial homogenates (IC₅₀=16.65 μM) . Idebenone, a coenzyme Q10 analog and an antioxidant, induces apoptotic cell death in the human dopaminergic neuroblastoma SHSY-5Y cells . Idebenone quickly crosses the blood-brain barrier.

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

10

Aminoguanidine hydrochloride

10 Cited Publications

Cat. No.: HY-B1041

CAS No.: 1937-19-5

Synonyms: Pimagedine hydrochloride; GER-11; Aminoguanidinium hydrochloride

Target:

NO Synthase Apoptosis ERK

Aminoguanidine (Pimagedine) hydrochloride is an inhibitor of diamine oxidase (DAO) and nitric oxide synthase (NOS). Aminoguanidine hydrochloride can reduce the formation of advanced glycation end products (AGEs). Aminoguanidine hydrochloride has a dose-dependent inhibitory effect on Doxorubicin (HY-15142)-induced cell apoptosis. Aminoguanidine hydrochloride has antioxidant properties. Aminoguanidine hydrochloride can be used in the research of diabetic nephropathy .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

10

Aminoguanidine hemisulfate

10 Cited Publications

Cat. No.: HY-W020772

CAS No.: 996-19-0

Synonyms: Pimagedine hemisulfate; GER-11 hemisulfate; Aminoguanidinium hemisulfate

Target:

NO Synthase Apoptosis ERK

Aminoguanidine (Pimagedine) hemisulfate is an inhibitor of diamine oxidase (DAO) and nitric oxide synthase (NOS). Aminoguanidine hemisulfate can reduce the formation of advanced glycation end products (AGEs). Aminoguanidine hemisulfate has a dose-dependent inhibitory effect on Doxorubicin (HY-15142)-induced cell apoptosis. Aminoguanidine hemisulfate has antioxidant properties. Aminoguanidine hemisulfate can be used in the research of diabetic nephropathy .

Compare

loading...