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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
antiparallel telo22
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "antiparallel telo22" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-148200A
Purity: 99.28%
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L2H2-6OTD diformic is a G-quadruplex (G-quadruplex, G4) ligand and telomerase (telomerase) inhibitor, with an IC50 of 15 nM against human telomerase. L2H2-6OTD diformic induces the formation of antiparallel G-quadruplex structures in long telomeric DNA. L2H2-6OTD diformic stabilizes the G4 structure of GD3 and enhances the immunological activity of CpG ODN. L2H2-6OTD diformic is applicable to research related to the development of G4-CpG immune adjuvants .
Cat. No.: HY-P3222
CAS No.: 20054-93-7
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Cat. No.: HY-P5917A
Synonyms: Vaejovis mexicanus peptide 24 TFA
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Astrophloxine is a fluorescent imaging probe capable of targeting antiparallel dimers. Astrophloxine can be used to detect aggregated Aβ in brain tissue and cerebrospinal fluid samples of Alzheimer's disease (AD) mice .
Cat. No.: HY-P1631
CAS No.: 125139-67-5
Cat. No.: HY-P5214
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Cat. No.: HY-P3222A
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Cat. No.: HY-P5340
CAS No.: 339091-39-3
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Cat. No.: HY-P5917
CAS No.: 1373890-79-9
Synonyms: Vaejovis mexicanus peptide 24
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Cat. No.: HY-187606
CAS No.: 216308-19-9
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DB293 is a dicationic bis-amidine compound that potently recognizes mixed base pair sequences. DB293 binds to the minor groove of the ATGA sequence as an antiparallel stacked dimer through positive cooperativity. DB293 forms monomeric complexes with ATATAT and AAATTT, with no significant selectivity preference for these two sequences .
Cat. No.: HY-P12358
CAS No.: 1245010-44-9
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SPG-178 is a synthetic neutral Self-assembling peptide. In neutral aqueous solution, SPG-178 spontaneously assembles into an antiparallel β-sheet nanoscale three-dimensional hydrogel (SPG-178-Gel) through electrostatic and hydrophobic interactions, and biologically mimics the natural extracellular matrix (ECM) to provide a microenvironment that promotes cell proliferation and angiogenesis .
Cat. No.: HY-187442
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TDI6245 is a Aurora kinase A (AURKA) inhibitor with an IC50 value of 21.64 nM against AURKA. TDI6245 also inhibits the β5 subunit of the 20S proteasome from Plasmodium falciparum (Pf 20S), with IC50 values of 0.11 μM, 31.1 μM and 6.8 μM against Pf 20S β5, human constitutive proteasome β5c and human immunoproteasome β5i subunits, respectively. TDI6245 binds to the AURKA pocket and the substrate cleft of Pf 20S β5 via antiparallel β-sheets and hydrogen bonds. TDI6245 inhibits the growth of Plasmodium falciparum. TDI6245 can be used in research related to triple-negative breast cancer and malaria .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
