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8 Results for "

antischizophrenia

" in MedChemExpress (MCE) Product Catalog:

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Glycerol dioleate

Cat. No.: HY-154487

CAS No.: 25637-84-7

Target:

Biochemical Assay Reagents

Research Areas:

Neurological Disease

Glycerol dioleate is a lipid capable of forming Lyotropic Liquid Crystal (LLC). When formulated with phosphatidylcholine and exposed to aqueous media, glycerol dioleate constructs an inverted hexagonal (H_II) phase structure with sustained-release properties. The in-situ forming gel prepared by optimizing glycerol dioleate with phosphatidylcholine and N-methyl-2-pyrrolidone enables stable release of Risperidone (HY-11018) for up to 60 days in vitro and in vivo. Glycerol dioleate causes minimal side effects in rabbits, making it an ideal carrier component for the development of antischizophrenia agents .Note: Lyotropic liquid crystals (Lyotropic Liquid Crystal, LLC) are ordered fluid phases self-assembled by amphipathic molecules (e.g., lipids, surfactants) in solvents (usually water) at specific concentrations .

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SSR504734

Cat. No.: HY-10715

CAS No.: 615571-23-8

Purity: 99.82%

Target:

GlyT

Research Areas:

Neurological Disease

SSR504734 is an orally active, selective and reversible inhibitor of human, rat, and mouse GlyT1 (IC₅₀=18, 15, and 38 nM, respectively). SSR504734 shows anti-schizophrenia, anti-anxiety and anti-depression activities .

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GPR139 agonist-2

Cat. No.: HY-149651

CAS No.: 2983118-29-0

Purity: 99.80%

Target:

GPR139

Research Areas:

Neurological Disease

GPR139 agonist-2 (compound 20a) is a potent GPR139 agonist with an EC₅₀ of 24.7 nM. GPR139 agonist-2 rescues the social interaction deficits and alleviates cognitive deficits in murine schizophrenia models. GPR139 agonist-2 has the potential for antischizophrenia drug research .

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