329 Results for "

arterial

" in MedChemExpress (MCE) Product Catalog:
Products (329)

329 Results for "arterial" in MCE Product Catalog:

22
IOX2
IOX2
0 Images
22 Publications Verification
Cat. No.: HY-15468
CAS No.: 931398-72-0
Purity:  98.02%
Target:  

HIF/HIF Prolyl-Hydroxylase

Research Areas:  

Cancer

IOX2, a chemical probe, is a specific prolyl hydroxylase-2 (PHD2) inhibitor with IC50 of 22 nM. IOX2 regulates platelet function and arterial thrombosis by upregulating HIF-1α expression and inhibiting ROS production. IOX2 can be used in the study of thrombotic diseases .
loading...
    loading...
View All Sizes
21
Nafamostat mesylate
Nafamostat mesylate
0 Images
21 Cited Publications
Cat. No.: HY-B0190A
CAS No.: 82956-11-4
Synonyms: FUT-175
Target:  

Flavivirus TNF Receptor NF-κB Apoptosis Ser/Thr Protease

Research Areas:  

Infection Cancer

Nafamostat mesylate (FUT-175), an anticoagulant, is a synthetic serine protease inhibitor. Nafamostat mesylate has anticancer and antivirus effect. Nafamostat mesylate induce apoptosis by up-regulating the expression of tumor necrosis factor receptor-1 (TNFR1). Nafamostat mesylate can be used in the development of the pathological thickening of the arterial wall .
loading...
    loading...
View All Sizes
14
Macitentan
Macitentan
0 Images
14 Cited Publications
Cat. No.: HY-14184
CAS No.: 441798-33-0
Purity:  99.85%
Synonyms: ACT-064992
Target:  

Endothelin Receptor Apoptosis

Research Areas:  

Cardiovascular Disease Endocrinology Cancer

Macitentan (ACT-064992) is an orally active, non-peptide dual ETA and ETB (endothelin receptor) antagonist. Macitentan has the potential for idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH) .
loading...
    loading...
View All Sizes
12
Adenosine 5'-diphosphate disodium
Adenosine 5'-diphosphate disodium
0 Images
12 Cited Publications
Cat. No.: HY-D0199
CAS No.: 16178-48-6
Synonyms: Adenosine diphosphate disodium; ADP disodium
Category:  

Ketones, Aldehydes, Acids Endogenous metabolite

Target:  

Endogenous Metabolite

Adenosine 5'-diphosphate disodium is a nucleoside diphosphate. Adenosine 5'-diphosphate disodium is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate disodium is a platelet aggregation agent for hemostasis and the development and extension of arterial thrombosis .
loading...
    loading...
View All Sizes
12
Ifenprodil
Ifenprodil
0 Images
12 Cited Publications
Cat. No.: HY-12882
CAS No.: 23210-56-2
Purity:  99.94%
Synonyms: NP-120; RC-61-91
Target:  

iGluR Adrenergic Receptor Potassium Channel Calcium Channel Influenza Virus

Research Areas:  

Infection Neurological Disease

Ifenprodil (NP-120), a cerebral vasodilator, is a noncompetitive NMDA receptor antagonist. Ifenprodil exerts high affinity at NR1A/NR2B receptors (IC50=0.34 μM) over 400-fold than at NR1A/NR2A receptors (IC50=146 μM) . Ifenprodil is an α1 adrenergic receptor antagonist. Ifenprodil inhibits GIRK (Kir3), reduces inward currents through the basal GIRK activity. Ifenprodil has reliable inhibitory effects against A/H1N1 strains (EC50 of 6.6 µM). Ifenprodil has neuroprotective, anticonvulsant and antinociceptive effects. Ifenprodil can be used for the study of cerebrovascular diseases and peripheral arterial obliterative disease .
loading...
    loading...
View All Sizes
12
Ifenprodil tartrate
Ifenprodil tartrate
0 Images
12 Cited Publications
Cat. No.: HY-12882A
CAS No.: 23210-58-4
Purity:  99.95%
Synonyms: NP-120 tartrate; RC-61-91 tartrate
Category:  

Alkaloids Piperidine Alkaloids Neurological Disease 500 - Internal Server Error | MedChemExpress

Oops!

Sorry, Something went wrong on our server.
Our team has been notified and is working to fix the issue.