84 Results for "

asparagine

" in MedChemExpress (MCE) Product Catalog:
Products (84)

84 Results for "asparagine" in MCE Product Catalog:

18
L-Asparaginase
L-Asparaginase
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18 Publications Verification
Cat. No.: HY-P1923
CAS No.: 9015-68-3
Synonyms: L-​ASNase
Target:  

Apoptosis DNA/RNA Synthesis

Research Areas:  

Cancer

L-Asparaginase (L-ASNase) is a deamidating enzyme that catalyses the hydrolysis of L-asparagine and L-glutamine, and can be used for the research of acute lymphoblastic leukemia. L-Asparaginase depletes L-asparagine from plasma resulting in inhibition of RNA and DNA synthesis with the subsequent blastic cell apoptosis .
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6
L-Asparagine
L-Asparagine
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6 Cited Publications
Cat. No.: HY-N0667
CAS No.: 70-47-3
Synonyms: (-)-asparagine; Asn; Asparamide
Category:  

Neurological Disease Amino acids Endogenous metabolite Disease Research Fields Cancer

Target:  

Endogenous Metabolite Apoptosis DNA/RNA Synthesis

L-Asparagine is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia .
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6
L-Asparagine monohydrate
L-Asparagine monohydrate
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6 Cited Publications
Cat. No.: HY-W017443
CAS No.: 5794-13-8
Category:  

Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite Apoptosis DNA/RNA Synthesis

L-Asparagine monohydrate is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine monohydrate can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia .
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5
Chebulagic acid
Chebulagic acid
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5 Cited Publications
Cat. No.: HY-N1996
CAS No.: 23094-71-5
Category:  

Combretaceae Extract Phenols Polyphenols 500 - Internal Server Error | MedChemExpress

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