76 Results for "

astrocytes

" in MedChemExpress (MCE) Product Catalog:
Products (76)

76 Results for "astrocytes" in MCE Product Catalog:

139
GsMTx4
GsMTx4
0 Images
139 Publications Verification
Cat. No.: HY-P1410
CAS No.: 1209500-46-8
Target:  

TRP Channel Piezo Channel

Research Areas:  

Cardiovascular Disease Neurological Disease Inflammation/Immunology

GsMTx4 is a spider venom peptide that selectively inhibits cationic-permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families. GsMTx4 also blocks cation-selective stretch-activated channels (SACs) , attenuates lysophosphatidylcholine (LPC)-induced astrocyte toxicity and microglial reactivity. GsMTx4 is an important pharmacological tool for identifying the role of these excitatory MSCs in normal physiology and pathology .
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139
GsMTx4 TFA
GsMTx4 TFA
0 Images
139 Publications Verification
Cat. No.: HY-P1410A
Target:  

TRP Channel Piezo Channel

Research Areas:  

Cardiovascular Disease Neurological Disease Inflammation/Immunology

GsMTx4 TFA is a spider venom peptide that selectively inhibits cationic-permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families. GsMTx4 TFA also blocks cation-selective stretch-activated channels (SACs) , attenuates lysophosphatidylcholine (LPC)-induced astrocyte toxicity and microglial reactivity. GsMTx4 TFA is an important pharmacological tool for identifying the role of these excitatory MSCs in normal physiology and pathology .
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20
SEA0400
SEA0400
0 Images
20 Cited Publications
Cat. No.: HY-15515
CAS No.: 223104-29-8
Purity:  99.95%
Target:  

Na+/Ca2+ Exchanger

Research Areas:  

Cardiovascular Disease

SEA0400 is a novel and selective inhibitor of the Na +-Ca 2+ exchanger (NCX), inhibiting Na +-dependent Ca 2+ uptake in cultured neurons, astrocytes, and microglia with IC50s of from 5 to 33 nM.
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8
Texas Red
Texas Red
0 Images
8 Cited Publications
Cat. No.: HY-101878
CAS No.: 60311-02-6
Purity:  99.72%
Synonyms: Sulforhodamine 101; SR101
Texas Red (Sulforhodamine 101) is an amphoteric rhodamine red fluorescent dye (excitation/emission: 586/605 nm). Texas Red is used extensively for investigating neuronal morphology and acts as acell type-selective fluorescent marker of astrocytes bothin vivoand in slice preparations .
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6
Clenbuterol hydrochloride
Clenbuterol hydrochloride
0 Images
6 Cited Publications
Cat. No.: HY-B1614
CAS No.: 21898-19-1
Synonyms: NAB-365 hydrochloride
Category:  

Natural Products Endogenous metabolite Disease Research Fields Inflammation/Immunology Endocrinology

Target:  

Adrenergic Receptor

Clenbuterol (NAB-365) hydrochloride, a selective β2-adrenergic agonist, enhances skeletal muscle strength and hypertrophy. Clenbuterol hydrochloride induces growth factor mRNA, activates astrocytes, and protects rat brain tissue against ischemic damage .
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5
SCH79797
SCH79797
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5 Cited Publications
Cat. No.: HY-14993
CAS No.: 245520-69-8
Purity:  99.74%
Target:  

Protease Activated Receptor (PAR) Apoptosis

Research Areas:  

Cardiovascular Disease

SCH79797 is a highly potent, selective nonpeptide protease activated receptor 1 (PAR1) antagonist. SCH79797 inhibits binding of a high-affinity thrombin receptor-activating peptide to PAR1 with an IC50 of 70 nM and a Ki of 35 nM. SCH79797 inhibits thrombin-induced platelet aggregation with an IC50 of 3 μM. SCH79797 has antiproliferative and pro-apoptotic effects, and limits myocardial ischemia/reperfusion injury in rat hearts. SCH79797 also potently prevents PAR1 activation in vascular smooth muscle cells, endothelial cells, and astrocytes .
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5
SCH79797 dihydrochloride
SCH79797 dihydrochloride
0 Images
5 Cited Publications
Cat. No.: HY-14994
CAS No.: 1216720-69-2
Purity:  99.91%
Target:  

Protease Activated Receptor (PAR) Apoptosis

Research Areas:  

Cardiovascular Disease

SCH79797 dihydrochloride is a highly potent, selective nonpeptide protease activated receptor 1 (PAR1) antagonist. SCH79797 dihydrochloride inhibits binding of a high-affinity thrombin receptor-activating peptide to PAR1 with an IC50 of 70 nM and a Ki of 35 nM. SCH79797 dihydrochloride inhibits thrombin-induced platelet aggregation with an IC50 of 3 μM. SCH79797 dihydrochloride has antiproliferative and pro-apoptotic effects, and limits myocardial ischemia/reperfusion injury in rat hearts. SCH79797 dihydrochloride also potently prevents PAR1 activation in vascular smooth muscle cells, endothelial cells, and astrocytes .
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4
Tyrosol
Tyrosol
0 Images
4 Cited Publications
Cat. No.: HY-N0474
CAS No.: 501-94-0
Category:  

Anti-aging Plants Endogenous metabolite Microorganisms Monophenols 500 - Internal Server Error | MedChemExpress

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