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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
autonomic
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "autonomic" in MCE Product Catalog:
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Eleclazine (GS 6615) hydrochloride is a selective cardiac late sodium current inhibitor and a weak inhibitor of potassium current with IC50 value of <1 μM and approximately 14.2 μM, respectively. Eleclazine hydrochloride shows concurrent protection against autonomically induced atrial premature beats, repolarization alternans and heterogeneity, and atrial fibrillation in porcine model. Eleclazine hydrochloride can be used to research cardiac arrhythmias .
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Target:
Research Areas:
Eleclazine (GS 6615) is a selective cardiac late sodium current inhibitor and a weak inhibitor of potassium current with IC50 of <1 μM and approximately 14.2 μM, respectively. Eleclazine shows concurrent protection against autonomically induced atrial premature beats, repolarization alternans and heterogeneity, and atrial fibrillation in porcine model. Eleclazine can be used to research cardiac arrhythmias .
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1 Cited Publications
Cat. No.: HY-P2847
CAS No.: 330648-32-3
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Cat. No.: HY-P1248
CAS No.: 99566-27-5
Synonyms: NPFF
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Cat. No.: HY-W127668
CAS No.: 5957-17-5
Cat. No.: HY-N2401
CAS No.: 18234-46-3
Category:
Valeriana jatamansi Jones Extract Natural Products Plant Valerianaceae Extract Valeriana officinalis Linn. Extract
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Ectylurea, a N-acylurea, can be used in studies of tension and anxiety symptoms, has no effect on the autonomic nervous system, and has no convulsive, analgesic or antispasmodic activity in animals .
Cat. No.: HY-106780
CAS No.: 104775-36-2
Synonyms: DQ 2511
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Ecabapide (DQ 2511) is an orally active gastroprokinetic agent. Ecabapide can ameliorate gastric emptying of stroke-prone spontaneously hypertensive rat model. Ecabapide can be studied in research on autonomic nervous system disorder .
Cat. No.: HY-113444
CAS No.: 71902-47-1
Synonyms: PGD3
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Prostaglandin D3 (PGD3) is a prostaglandin that acts as an inhibitor of platelet aggregation and a modulator of autonomic neurotransmission in humans .
Cat. No.: HY-W015160
CAS No.: 5321-48-2
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1-(3-Methylbenzyl)piperazine is a derivative of Benzylpiperazine that affects the central and the autonomic nervous systems, the blood pressure, and smooth muscle .
Cat. No.: HY-B0639C
CAS No.: 59178-37-9
Synonyms: WR2721 sodium
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Amifostine sodium (WR2721 sodium) is a phosphorus sulfate with radioprotective activity. Amifostine sodium can cause splenic vasodilation and may block autonomic ganglia. Amifostine sodium is clinically used to prevent cisplatin-induced ototoxicity .
Cat. No.: HY-174778
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Human ASCL1 mRNA encodes the human achaete-scute family bHLH transcription factor 1 (ASCL1) protein, a member of the basic helix-loop-helix (BHLH) family. ASCL1 plays a role in the neuronal commitment and differentiation, and in the generation of olfactory and autonomic neurons.
Cat. No.: HY-16738AR
CAS No.: 1448754-43-5
Synonyms: GS 6615 hydrochloride (Standard)
Research Areas:
Eleclazine (hydrochloride) (Standard) is the analytical standard of Eleclazine (hydrochloride). This product is intended for research and analytical applications. Eleclazine (GS 6615) hydrochloride is a selective cardiac late sodium current inhibitor and a weak inhibitor of potassium current with IC50 value of <1 μM and approximately 14.2 μM, respectively. Eleclazine hydrochloride shows concurrent protection against autonomically induced atrial premature beats, repolarization alternans and heterogeneity, and atrial fibrillation in porcine model. Eleclazine hydrochloride can be used to research cardiac arrhythmias .
Cat. No.: HY-12502C
CAS No.: 128194-13-8
Synonyms: (R)-NZ-105; (-)-Efonidipine
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(R)-Efonidipine ((R)-NZ-105) is an orally active, selective T-type Ca 2+ channel blocker. (R)-Efonidipine does not inhibit high-voltage-activated Ca 2+ channels, voltage-dependent Na + channels, or Ca 2+-activated K + channels. (R)-Efonidipine modulates cardiac autonomic function by increasing parasympathetic activity and decreasing sympathetic activity. (R)-Efonidipine significantly improves survival in a mouse model of dilated cardiomyopathy. (R)-Efonidipine can be used in research on ischemic encephalopathy, heart failure, and hypertension .
Cat. No.: HY-106698
CAS No.: 57475-17-9
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Brovincamine is an orally active slow Ca 2+ channel blocker and vasodilator. Brovincamine reduces Ca 2+ influx across the plasma membrane by blocking Ca 2+ channels. Brovincamine inhibits catecholamine secretion, cholinergic function, autonomic parasympathetic nervous system activity, cerebrovascular resistance, and nerve stimulation-induced convulsive responses. Brovincamine induces cerebrovascular, coronary, and intracranial vasodilation, improves cerebral cortical microcirculation, enhances cerebral metabolic activity, and increases capillary clearance efficiency. Brovincamine can be used in research related to cerebral ischemic diseases, cardiac ischemic diseases, and normal-tension glaucoma .
Cat. No.: HY-P85195
Synonyms: HAND1; BHLHA27; EHAND; Heart- and neural crest derivatives-expressed protein 1; Class A basic helix-loop-helix protein 27; bHLHa27; Extraembryonic tissues; heart, autonomic nervous system and neural crest derivatives-expressed protein 1; eH
Cat. No.: HY-P85195A
Synonyms: HAND1; BHLHA27; EHAND; Heart- and neural crest derivatives-expressed protein 1; Class A basic helix-loop-helix protein 27; bHLHa27; Extraembryonic tissues; heart, autonomic nervous system and neural crest derivatives-expressed protein 1; eH
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
