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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
163 Results for "
bacterial strains
" in MedChemExpress (MCE) Product Catalog:
Products (163)
163 Results for "bacterial strains" in MCE Product Catalog:
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8 Cited Publications
Target:
Rifaximin, a gastrointestinal-selective antibiotic, binds the β-subunit of bacterial DNA-dependent RNA polymerase, resulting in inhibition of bacterial RNA synthesis. Rifaximin susceptibility is higher against Gram-positive strains (MIC: 0.03-5 mg/ml) compared to Gram-negative bacteria (MIC: 8-50 mg/mL) .
2
Research Areas:
N-3-oxo-dodecanoyl-L-Homoserine lactone (3-oxo-C12-HSL) is a bacterial quorum-sensing signaling molecule produced by P. aeruginosa and strains of the B. cepacia complex .Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density.N-3-oxo-dodecanoyl-L-Homoserine lactone induces the production of IL-8 in 16HBE human bronchial epithelial cells .
1
Category:
Infection Antibiotics Resistance Selection Microorganism Disease Research Antibacterial Disease Research Fields Other Antibiotics
Target:
Ribostamycin sulfate (Vistamycin sulfate) is a broad-spectrum aminoglycoside Antibiotic with bactericidal activity against Gram-positive cocci, Gram-negative cocci, bacilli, and drug-resistant strains. Ribostamycin sulfate also acts as an inhibitor of protein disulfide isomerase (PDI), with a binding constant KD of 319 μM for bovine PDI. Ribostamycin sulfate targets bacterial 16S ribosomal RNA and the 30S ribosomal subunit, causing translational misreading and thereby inhibiting bacterial protein synthesis. Ribostamycin sulfate disrupts the integrity of bacterial cell membranes, induces membrane pore formation, and leads to bacterial death. Ribostamycin sulfate can be used in studies related to bacterial infections .
1
1 Cited Publications
Furanone C-30 is a quorum sensing inhibitor. Furanone C-30 can effectively inhibit bacterial biofilm formation by S. mutans and its luxSmutant strain .
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Cefpirome (HR-810) sulfate is a cephalosporin antibiotic that can cross cell membranes and the blood-brain barrier. Cefpirome sulfate binds to penicillin-binding proteins with high affinity, thereby inhibiting bacterial cell wall synthesis. Cefpirome sulfate exhibits bactericidal and growth-inhibitory activities against Gram-negative bacteria, Gram-positive bacteria, and susceptible anaerobic bacteria (including some β-lactamase-producing strains) .
1
Category:
Infection Macrolide Antibiotics Antibiotics Anti-parasitic Microorganism Disease Research Antibacterial Disease Research Fields
Target:
Category:
Infection Antibiotics Microorganism Disease Research Antibacterial Disease Research Fields Other Antibiotics
Target:
Cat. No.: HY-17028
CAS No.: 405165-61-9
Research Areas:
Besifloxacin Hydrochloride is a fourth generation fluoroquinolone antibiotic. Besifloxacin Hydrochloride is a DNA gyrase and topoisomerase IV inhibitor. Besifloxacin Hydrochloride has broad-spectrum antibacterial activity, it is effective against Gram-negative and Gram-positive aerobic and anaerobic strains and reduces the incidence of drug resistance. Besifloxacin Hydrochloride has anti-inflammatory activity. Besifloxacin Hydrochloride can be used in bacterial conjunctivitis research .
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Flurofamide is an effective bacterial urease inhibitor and antibacterial agent. Flurofamide inhibits urease and partially inhibits the chemotactic activity of Helicobacter pylori strain CPY3401. Flurofamide inhibits the growth of Ureaplasma urealyticum. Flurofamide reduces blood ammonia. Flurofamide can be used in the research of infectious urinary stones .
Cat. No.: HY-125733
CAS No.: 59979-01-0
Category:
Target:
Cat. No.: HY-P10233A
Cat. No.: HY-125576
CAS No.: 26034-16-2
Cat. No.: HY-20349
CAS No.: 30233-64-8
Monobehenin, an bacterial biofilm formation inhibitor, has strong inhibitory activity toward bacterial biofilm formation of S. mutans, X. oryzae, and Y. enterocolitica in a strain specific manner .
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Sulfamethoxypyridazine is an orally active and brain-penetrant sulfonamide antibiotic. Sulfamethoxypyridazine exhibits antibacterial activity and inhibits growth of susceptible bacterial strains. Sulfamethoxypyridazine can be used for the research of pyelonephritis, urinary tract infections, and dermatitis herpetiformis .
Cat. No.: HY-156264
CAS No.: 86482-18-0
Synonyms: Ticarcillin-clavulanic acid mixt.; BRL28500
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Research Areas:
Augpenin (Ticarcillin-clavulanic acid mixt.; BRL28500) is a compound β-lactam antibacterial mixture of Ticarcillin (HY-139805) and Clavulanic acid (HY-A0256) in a 15:1 ratio. Ticarcillin in Augpenin acts on bacterial penicillin-binding proteins, while Clavulanic acid acts as an irreversible β-lactamase inhibitor that protects Ticarcillin from hydrolysis and restores its inhibitory activity against resistant strains. Augpenin significantly reduces the bacterial load of Legionella pneumophila in lung tissue of Cyclophosphamide (HY-17420)-induced neutropenic young rats. Augpenin can be used in research related to bacterial infections .
Cat. No.: HY-P3328A
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
