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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
48 Results for "
benzamid
" in MedChemExpress (MCE) Product Catalog:
Products (48)
48 Results for "benzamid" in MCE Product Catalog:
4
4 Cited Publications
Cat. No.: HY-W018781
CAS No.: 1670-14-0
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Benzamidine hydrochloride is a competitive protease inhibitor that blocks the hydrolytic cleavage of glucagon by plasmin, trypsin and thrombin. Benzamidine hydrochloride effectively inhibits the degradation of glucagon by relevant proteases during the collection, storage and analysis of human plasma and blood samples. During in vivo metabolism, Benzamidine hydrochloride undergoes N-hydroxylation and produces multiple metabolites, exhibiting characteristics of delayed excretion or biphasic elimination. Benzamidine hydrochloride only induces slight single-strand DNA breaks at high concentrations and shows no significant genotoxic potential overall. Benzamidine hydrochloride may interfere with the detection of some glucagon antisera, but does not affect key antigen-antibody affinity at specific concentrations. Benzamidine hydrochloride can be used as a stabilizer in glucagon radioimmunoassays to ensure the accuracy and recovery rate of detection results .
4
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Benzamidine is a competitive protease inhibitor that blocks the hydrolytic cleavage of glucagon by plasmin, trypsin and thrombin. Benzamidine effectively inhibits the degradation of glucagon by relevant proteases during the collection, storage and analysis of human plasma and blood samples. During in vivo metabolism, Benzamidine undergoes N-hydroxylation and produces multiple metabolites, exhibiting characteristics of delayed excretion or biphasic elimination. Benzamidine only induces slight single-strand DNA breaks at high concentrations and shows no significant genotoxic potential overall. Benzamidine may interfere with the detection of some glucagon antisera, but does not affect key antigen-antibody affinity at specific concentrations. Benzamidine can be used as a stabilizer in glucagon radioimmunoassays to ensure the accuracy and recovery rate of detection results .
4
4 Cited Publications
Cat. No.: HY-W087937
CAS No.: 206752-36-5
Synonyms: Benzenecarboximidamide hydrochloride hydrate
1
Category:
Alkaloids Human Gut Microbiota Metabolites Other Alkaloids Other Diseases Endogenous metabolite Disease Research Fields
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GDC-046 is a potent, selective, and orally bioavailable TYK2 inhibitor with Kis of 4.8, 0.7, 0.7, and 0.4 nM for TYK2, JAK1, JAK2, and JAK3, respectively .
Synonyms: ABAO
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2-Amino benzamidoxime (ABAO) acts as a bioconjugation reagent precursor and a fluorescent probe precursor. 2-Amino benzamidoxime contains an aniline group for imine activation of aldehydes, as well as a nucleophilic group (Nu:) located at the ortho position of the amine, which is responsible for intramolecular cyclization. 2-Amino benzamidoxime reacts with glyoxal at the N-terminus of phage-displayed peptide libraries. Derivatives of 2-Amino benzamidoxime can be used for protein bioconjugation. Derivatives of 2-Amino benzamidoxime serve as fluorescent probes .\n
Cat. No.: HY-46395
CAS No.: 1662687-79-7
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6-(4-(Methoxymethoxy)benzamido)imidazo[1,2-a]pyridine-2-carboxylic acid is a drug intermediate for synthesis of various active compounds.
Synonyms: N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide
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Cat. No.: HY-W016562S
CAS No.: 53518-98-2
Synonyms: 2-benzamidoacetic acid-d5
Cat. No.: HY-147342
CAS No.: 156724-91-3
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β-Benzamide adenine dinucleotide is a biologically active metabolite of benzamide riboside. β-Benzamide adenine dinucleotide is a competitive inhibitor of human NAD kinase with a Ki value of 90 μM, and inhibits human IMPDH with IC50 values of 0.787 μM and 0.884 μM for type I and type II, respectively. β-Benzamide adenine dinucleotide exhibits inhibitory activities against lactate dehydrogenase, glutamate dehydrogenase, and malate dehydrogenase. β-Benzamide adenine dinucleotide can be used for the study of chronic myelogenous leukemia .
Cat. No.: HY-W016562S1
CAS No.: 208928-78-3
Synonyms: 2-benzamidoacetic acid-d2
Cat. No.: HY-Z0283S
CAS No.: 31656-62-9
Synonyms: Benzenecarboxamide-15N; Phenylamide-15N
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2-Amino-N-(pyridin-3-ylmethyl)benzamide is a drug intermediate for synthesis of various active compounds.
Cat. No.: HY-403978S
CAS No.: 1447799-45-2
Cat. No.: HY-W711852
CAS No.: 1235489-47-0
Synonyms: Benzenecarboxamide-d5; Phenylamide-d5
Cat. No.: HY-W117416
CAS No.: 1449134-30-8
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N-(3-Hydroxypropyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide is a PROTAC linker that can be used in the synthesis of PROTACs.
Cat. No.: HY-75204
CAS No.: 17794-48-8
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2-(3-(Trifluoromethyl)benzamido)acetic acid is a drug intermediate for synthesis of various active compounds.
Cat. No.: HY-W520657
CAS No.: 23076-31-5
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2-Amino-5-nitro-N-(o-tolyl)benzamide is a drug intermediate for synthesis of various active compounds.
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MethylCBI-azaindole-benzamide-MOM-Boc-ethylenediamine-D is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
Synonyms: 4-Amino-N-(4-trifluoromethylphenyl)benzamide
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Teriflunomide impurity 3 (4-Amino-N-(4-trifluoromethylphenyl)benzamide) is a selective COX-1 inhibitor with an IC50 of 30 µM. Teriflunomide impurity 3 is less active against COX-2 (IC50>100 µM) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
