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146 Results for "

beta subunits

" in MedChemExpress (MCE) Product Catalog:

Products (146)

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Lificiguat

37 Publications Verification

Cat. No.: HY-14927

CAS No.: 170632-47-0

Purity: 99.70%

Synonyms: YC-1

Target:

Guanylate Cyclase

Research Areas:

Cardiovascular Disease Cancer

Lificiguat binds to the β subunit of soluble guanylyl cyclase(sGC) with K_d of 0.6-1.1 μM in the presence of CO.

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Kartogenin

34 Cited Publications

Cat. No.: HY-16268

CAS No.: 4727-31-5

Synonyms: KGN

Target:

TGF-beta/Smad

Research Areas:

Inflammation/Immunology

Kartogenin (KGN) is an inducer of chondrogenic tissue formation (EC₅₀: 100 nM). Kartogenin induces chondrogenesis by binding to fibrin A, disrupting its interaction with the transcription factor core binding factor beta subunit (CBFβ), and by modulating the CBFβ-RUNX1 transcriptional program. Kartogenin also promotes tendon-bone junction (TBJ) wound healing by stimulating collagen synthesis. Kartogenin is widely used in cell-free therapy in the field of regeneration for cartilage regeneration and protection, tendon-bone healing, wound healing and limb development. Kartogenin promotes cartilage repair, coordinates limb development, and is also used in osteoarthritis (OA) research .

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Kartogenin sodium

34 Cited Publications

Cat. No.: HY-16268A

CAS No.: 1401168-39-5

Synonyms: KGN sodium

Target:

TGF-beta/Smad

Research Areas:

Inflammation/Immunology

Kartogenin (KGN) sodium is an inducer of chondrogenic tissue formation (EC₅₀: 100 nM). Kartogenin sodium induces chondrogenesis by binding to fibrin A, disrupting its interaction with the transcription factor core binding factor beta subunit (CBFβ), and by modulating the CBFβ-RUNX1 transcriptional program. Kartogenin sodium also promotes tendon-bone junction (TBJ) wound healing by stimulating collagen synthesis. Kartogenin sodium is widely used in cell-free therapy in the field of regeneration for cartilage regeneration and protection, tendon-bone healing, wound healing and limb development. Kartogenin sodium promotes cartilage repair, coordinates limb development, and is also used in osteoarthritis (OA) research .

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