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202 Results for "

binding property

" in MedChemExpress (MCE) Product Catalog:

Products (202)

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111

Tacrolimus

111 Publications Verification

Cat. No.: HY-13756

CAS No.: 104987-11-3

Purity: 99.93%

Synonyms: FK506; Fujimycin; FR900506

Category:

Infection Microorganisms Animals Macrolide Antibiotics Anti-inflammation/Immunoregulatory Antibiotics Disease Research Disease Research Fields Inflammation/Immunology

Target:

Phosphatase FKBP Molecular Glues Bacterial Autophagy Antibiotic

Tacrolimus (FK506), a molecular glue, a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties .

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111

Tacrolimus monohydrate

111 Publications Verification

Cat. No.: HY-13756A

CAS No.: 109581-93-3

Purity: 99.67%

Synonyms: FK506 monohydrate; Fujimycin monohydrate; FR900506 monohydrate

Category:

Infection Microorganisms Macrolide Antibiotics Anti-inflammation/Immunoregulatory Antibiotics Disease Research Disease Research Fields Inflammation/Immunology

Target:

Phosphatase FKBP Molecular Glues Bacterial Autophagy Antibiotic

Tacrolimus (FK506) monohydrate, a molecular glue, a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus monohydrate inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties .

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Minocycline hydrochloride

76 Cited Publications

Cat. No.: HY-17412

CAS No.: 13614-98-7

Target:

Bacterial Antibiotic HIF/HIF Prolyl-Hydroxylase Apoptosis MDM-2/p53 Potassium Channel Calcium Channel

Research Areas:

Infection Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology Cancer

Minocycline hydrochloride is an orally active, potent and BBB-penetrated semi-synthetic tetracycline antibiotic. Minocycline hydrochloride is a hypoxia-inducible factor (HIF)-1α inhibitor. Minocycline hydrochloride shows anti-cancer, anti-inflammatory, and glutamate antagonist effects. Minocycline hydrochloride reduces glutamate neurotransmission and shows neuroprotective properties and antidepressant effects. Minocycline hydrochloride inhibits bacterial protein synthesis through binding with the 30S subunit of the bacterial ribosome, resulting in a bacteriostatic effect .

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Minocycline

76 Cited Publications

Cat. No.: HY-17412A

CAS No.: 10118-90-8

Target:

Antibiotic Bacterial HIF/HIF Prolyl-Hydroxylase Apoptosis MDM-2/p53 Potassium Channel Calcium Channel

Research Areas:

Infection Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology Cancer

Minocycline is an orally active, potent and BBB-penetrated semi-synthetic tetracycline antibiotic. Minocycline is a hypoxia-inducible factor (HIF)-1α inhibitor. Minocycline shows anti-cancer, anti-inflammatory, and glutamate antagonist effects. Minocycline reduces glutamate neurotransmission and shows neuroprotective properties and antidepressant effects. Minocycline inhibits bacterial protein synthesis through binding with the 30S subunit of the bacterial ribosome, resulting in a bacteriostatic effect .

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