4451 Results for "

biological

" in MedChemExpress (MCE) Product Catalog:

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399

Dimethyl sulfoxide, meets analytical specification of Ch.P.

399 Publications Verification

Cat. No.: HY-Y0320

CAS No.: 67-68-5

Synonyms: DMSO, meets analytical specification of Ch.P.

Dimethyl sulfoxide (DMSO), meets analytical specification of Ch.P. is an aprotic solvent that dissolves polar and non-polar compounds, including water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and can rapidly penetrate or enhance the penetration of other substances into biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity. Dimethyl sulfoxide also exhibits antifreeze and antibacterial properties .
MCE provides Dimethyl sulfoxide that complies with the inspection standards (Ch.P) of Part 4 of the Chinese Pharmacopoeia (2020 Edition). Amicrobic, low endotoxin, can be used in various biochemical experiments such as drug dissolution.

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MPTP hydrochloride

96 Cited Publications

Cat. No.: HY-15608

CAS No.: 23007-85-4

Purity: 99.52%

Target:

Dopamine Receptor Apoptosis

Research Areas:

Neurological Disease Inflammation/Immunology

MPTP hydrochloride is a brain penetrant dopaminergic neurotoxin. MPTP hydrochloride can be used to induce Parkinson’s Disease model. MPTP hydrochloride, a precusor of MPP ⁺, induces apoptosis . MPTP hydrochloride has been verified by MCE with professional biological experiments.

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Dimethyl sulfoxide

66 Cited Publications

Cat. No.: HY-Y0320C

CAS No.: 67-68-5

Synonyms: DMSO

Dimethyl sulfoxide (DMSO) is an aprotic solvent that can dissolve water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and has the ability to rapidly penetrate or enhance the penetration of other substances through biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity .
Low endotoxin, can be used in various biochemical experiments such as drug dissolution.

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Ammonium chloride, AR, 99.5%

64 Cited Publications

Cat. No.: HY-Y1269

CAS No.: 12125-02-9

Ammonium chloride, as a heteropolar compound with pH value regulation, can cause intracellular alkalization and metabolic acidosis thus effecting enzymatic activity and influencing the process of biological system. Ammonium chloride is an autophagy inhibitor. Ammonium chloride is also a lysosome inhibitor .

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Ammonium chloride, for cell culture

64 Cited Publications

Cat. No.: HY-Y1269C

CAS No.: 12125-02-9

Synonyms: Salmiac, for cell culture

Ammonium chloride, for cell culture (Salmiac, for cell culture) is a reagent that can be used in cell culture to provide a source of nitrogen. Ammonium chloride can be used as a heteropolar compound to regulate pH value, which can cause intracellular alkalination and metabolic acidosis, thus affecting the activity of enzymes and affecting the process of biological systems. Ammonium chloride acts as an autophagy inhibitor.Ammonium chloride is also a lysosome inhibitor.

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Doramapimod hydrochloride

56 Cited Publications

Cat. No.: HY-10320A

CAS No.: 1283526-53-3

Synonyms: BIRB 796 hydrochloride

Target:

Autophagy Raf p38 MAPK

Research Areas:

Inflammation/Immunology

Doramapimod hydrochloride (BIRB 796 hydrochloride) is an anti-inflammatory compound with biological activity through inhibition of p38 MAPK. Doramapimod hydrochloride can significantly inhibit the activities of TNF-α and IL-1β induced by LPS, LTA and PGN. Doramapimod hydrochloride showed a stronger inhibitory effect on inflammation induced by all three bacterial toxins, which was more significant compared with the effects of other compounds. Doramapimod hydrochloride can be used in the research of autoimmune diseases .

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AP20187

55 Cited Publications

Cat. No.: HY-13992

CAS No.: 195514-80-8

Purity: 99.85%

Synonyms: B/B Homodimerizer

Target:

FKBP

Research Areas:

Metabolic Disease

AP20187 (B/B Homodimerizer) is a cell-permeable ligand used to dimerize FK506-binding protein (FKBP) fusion proteins and initiate biological signaling cascades and gene expression or disrupt protein-protein interactions.

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ATP Assay Kit

52 Cited Publications

Cat. No.: HY-K0314

MCE ATP Assay Kit provides a rapid method to measure intracellular ATP. The kit is suitable for ATP determination in cells, tissue, and other biological samples.

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Niclosamide

47 Cited Publications

Cat. No.: HY-B0497

CAS No.: 50-65-7

Synonyms: BAY2353

Target:

Environmental Pollutants Antibiotic Parasite STAT

Research Areas:

Infection Cancer

Niclosamide (BAY2353) is an orally active antihelminthic agent used in parasitic infection research . Niclosamide is a STAT3 inhibitor with an IC₅₀ of 0.25 μM in HeLa cells . Niclosamide has biological activities against cancer, inhibits DNA replication in Vero E6 cells .

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Niclosamide olamine

47 Cited Publications

Cat. No.: HY-B0497C

CAS No.: 1420-04-8

Synonyms: BAY2353 olamine

Target:

Environmental Pollutants Antibiotic STAT Parasite

Research Areas:

Infection Cancer

Niclosamide (BAY2353) olamine is an orally active antihelminthic agent used in parasitic infection research . Niclosamide olamin is a STAT3 inhibitor with an IC₅₀ of 0.25 μM in HeLa cells . Niclosamide olamin has biological activities against cancer, and inhibits DNA replication in Vero E6 cells .

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