599 Results for "

biological systems

" in MedChemExpress (MCE) Product Catalog:
Products (599)

599 Results for "biological systems" in MCE Product Catalog:

64
Ammonium chloride, AR, 99.5%
Ammonium chloride, AR, 99.5%
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64 Publications Verification
Cat. No.: HY-Y1269
CAS No.: 12125-02-9
Ammonium chloride, as a heteropolar compound with pH value regulation, can cause intracellular alkalization and metabolic acidosis thus effecting enzymatic activity and influencing the process of biological system. Ammonium chloride is an autophagy inhibitor. Ammonium chloride is also a lysosome inhibitor .
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64
Ammonium chloride, for cell culture
Ammonium chloride, for cell culture
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64 Publications Verification
Cat. No.: HY-Y1269C
CAS No.: 12125-02-9
Synonyms: Salmiac, for cell culture
Ammonium chloride, for cell culture (Salmiac, for cell culture) is a reagent that can be used in cell culture to provide a source of nitrogen. Ammonium chloride can be used as a heteropolar compound to regulate pH value, which can cause intracellular alkalination and metabolic acidosis, thus affecting the activity of enzymes and affecting the process of biological systems. Ammonium chloride acts as an autophagy inhibitor.Ammonium chloride is also a lysosome inhibitor.
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17
Arctigenin
Arctigenin
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17 Cited Publications
Cat. No.: HY-N0035
CAS No.: 7770-78-7
Synonyms: (-)-Arctigenin
Category:  

Neurological Disease Anti-aging Lignans Metabolic Disease Compositae/Asteraceae Extract Endogenous metabolite Infection Human Gut Microbiota Metabolites Plant Arctium lappa L. Extract Phenylpropanoids Disease Research Fields Inflammation/Immunology Cancer

Target:  

MMP Influenza Virus Autophagy Apoptosis

Arctigenin ((-)-Arctigenin), a biologically active lignan, can be used as an antitumor agent. Arctigenin exhibits potent antioxidant, anti-inflammatory and antiviral (influenza A virus) activities. Arctigenin can be used for the research of metabolic disorders, and central nervous system dysfunctions .
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14
L-Cysteine hydrochloride
L-Cysteine hydrochloride
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14 Cited Publications
Cat. No.: HY-Y0337A
CAS No.: 52-89-1
Category:  

Anti-aging Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

L-Cysteine hydrochloride is an orally active conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine hydrochloride suppresses ghrelin and reduces appetite in rodents. L-Cysteine hydrochloride inhibits Aspergillus flavus growth and AFB synthesis by disrupting cell structure and antioxidant system balance. L-Cysteine hydrochloride enhances relaxant responses of rat aortic rings to NO and reduces responses to endothelium-derived relaxing factor (EDRF) .
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7
Secalciferol
Secalciferol
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7 Cited Publications
Cat. No.: HY-32343
CAS No.: 55721-11-4
Synonyms: (24R)-24,25-Dihydroxyvitamin D3
Category:  

Endogenous metabolite Disease Research Fields Inflammation/Immunology Steroids

Target:  

Endogenous Metabolite VD/VDR

Secalciferol ((24R)-24,25-Dihydroxyvitamin D3) is the major active metabolite of Vitamin D. Secalciferol activates vitamin D receptor (VDR) with an EC50 value of 150 nM. Secalciferol is involved in a wide range of biological functions such as calcium homeostasis, cellular differentiation and proliferation processes, as well as other functions related to the immune system, which is promising for research of rickets, osteomalacia, hypercalcemia and autoimmune disorders .
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5
Avatrombopag
Avatrombopag
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5 Cited Publications
Cat. No.: HY-13463
CAS No.: 570406-98-3
Purity:  99.83%
Synonyms: AKR-501; E5501; YM477
Target:  

Thrombopoietin Receptor

Research Areas:  

Inflammation/Immunology Cancer

Avatrombopag (AKR-501) is an orally active, nonpeptide thrombopoietin (TPO) receptor agonist (EC50=3.3 nM). Avatrombopag mimics the biological activities of TPO. Avatrombopag increases platelet production by activating the intracellular signaling system, and promotes production of platelets and megakaryocytes from hemopoietic precursor cells. Avatrombopag is a substrate of cytochrome P450 (CYP) 2C9 and CYP3A .
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5
Avatrombopag maleate
Avatrombopag maleate
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5 Cited Publications
Cat. No.: HY-13463A
CAS No.: 677007-74-8
Purity:  99.88%
Synonyms: AKR-501 maleate; E5501 maleate; YM477 maleate
Target:  

Thrombopoietin Receptor Cytochrome P450 ERK STAT

Research Areas:  

Neurological Disease Metabolic Disease Inflammation/Immunology Cancer

Avatrombopag (AKR-501) maleate is an orally active, non-peptide thrombopoietin receptor (TPO receptor) agonist (EC50: 3.3 nM). Avatrombopag maleate mimics the biological activity of TPO. Avatrombopag maleate increases platelet production by activating intracellular signaling systems and promotes the production of platelets and megakaryocytes from hematopoietic precursor cells. Avatrombopag maleate is a substrate for cytochrome P450 (CYP) 2C9 and CYP3A .
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5
Avatrombopag hydrochloride
Avatrombopag hydrochloride
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5 Cited Publications
Cat. No.: HY-13463B
CAS No.: 570403-17-7
Purity:  97.05%
Synonyms: AKR-501 hydrochloride; E5501 hydrochloride; YM477 hydrochloride
Target:  

Thrombopoietin Receptor

Research Areas:  

Cardiovascular Disease Cancer

Avatrombopag (AKR-501) hydrochloride is an orally active, nonpeptide thrombopoietin (TPO) receptor agonist (EC50=3.3 nM). Avatrombopag hydrochloride mimics the biological activities of TPO. Avatrombopag hydrochloride increases platelet production by activating the intracellular signaling system, and promotes production of platelets and megakaryocytes from hemopoietic precursor cells. Avatrombopag hydrochloride is a substrate of cytochrome P450 (CYP) 2C9 and CYP3A .
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4
Spinosad
Spinosad
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4 Cited Publications
Cat. No.: HY-138800
CAS No.: 168316-95-8
Purity:  96.19%
Category:  

Natural Products Neurological Disease Microorganism Disease Research Fields Biological Pesticide Research Agricultural Research

Target:  

nAChR

Spinosad, a mixture of spinosyns A and D known as fermentation products of a soil actinomycete (Saccharopolyspora spinosa), is a biological neurotoxic insecticide with a broader action spectrum. Spinosad targets the nicotinic acetylcholine receptor (nAChRs) of the insect nervous system. Spinosad has an excellent environmental and mammalian toxicological profile. Larvicidal activity .
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3
Bathocuproine disulfonate disodium
Bathocuproine disulfonate disodium
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3 Cited Publications
Cat. No.: HY-W034953
CAS No.: 52698-84-7
Bathocuproine disulfonate disodium (BCS) is an organic compound used as a highly sensitive colorimetric reagent for copper ions in biochemical and analytical applications. It has a bright yellow color and absorbs light at specific wavelengths, so it can be used to detect and quantify trace copper. In biochemical applications, BCS is commonly used to study the role of copper ions in various biological processes. Copper is an essential nutrient for many organisms, but it can also be toxic in high concentrations, so accurate measurement of copper levels is important to understand its impact on living systems. In terms of analysis, BCS is often used in environmental monitoring and water quality testing to detect copper pollution. It can detect copper even at very low concentrations, making it an invaluable tool for identifying potential sources of pollution and assessing the impact of industrial activities on aquatic ecosystems.
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2
Pseudomonas quinolone signal
Pseudomonas quinolone signal
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2 Cited Publications
Cat. No.: HY-128200
CAS No.: 108985-27-9
Purity:  99.84%
Synonyms: PQS
Target:  

Bacterial

Research Areas:  

Infection Inflammation/Immunology

Pseudomonas quinolone signal (PQS) is a quorum-sensing signaling molecule produced by Pseudomonas aeruginosa. The synthesis of Pseudomonas quinolone signal relies on the las quorum-sensing system, and its biological activity is associated with the rhl system. Pseudomonas quinolone signal regulates the expression of the virulence gene lasB. Additionally, Pseudomonas quinolone signal plays roles in iron acquisition, cytotoxicity, outer-membrane vesicle biogenesis, and host immune modulation .
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1
Tempone-H
Tempone-H
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1 Cited Publications
Cat. No.: HY-23033
CAS No.: 3637-11-4
Target:  

Biochemical Assay Reagents

Research Areas:  

Neurological Disease

Tempone-H may be used as a spin trap in chemical and biological systems to quantify peroxynitrite and superoxide radical formation. Ferric and cupric ions are effective oxidants of Tempone-H .
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1
Parishin B
Parishin B
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1 Cited Publications
Cat. No.: HY-N2124
CAS No.: 174972-79-3
Category:  

Plant Orchidaceae Extract Gastrodia elata Bl. Extract Phenols Disease Research Fields Cancer

Target:  

Reactive Oxygen Species (ROS) Ferroptosis Apoptosis

Parishin B is a multi-target biological agent with anti-epileptic, anti-fascioliasis and anti-breast cancer lung metastasis activities . Parishin B regulates the gene/protein activities of ACLY, unc13c, γ-aminobutynergic system, pro-inflammatory system, antioxidant system, monoaminergic system, ferroptosis-related pathways, as well as GST, CatL, Trx and TRIB3 . Parishin B modulates energy-lipid metabolism, synaptic function, neurotransmitter balance, neuroinflammation, oxidative stress, parasite detoxification/invasion processes, as well as apoptosis, cell cycle, proliferation and metastasis of cancer cells [1][2][3]. Parishin B can be used for related research of epilepsy, fascioliasis and breast cancer lung metastasis [3].
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1
Lewis-b tetrasaccharide
Lewis-b tetrasaccharide
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1 Cited Publications
Cat. No.: HY-W854445
CAS No.: 80081-06-7
Lewis-b tetrasaccharide is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
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1
N-Aminofluorescein
N-Aminofluorescein
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1 Cited Publications
Cat. No.: HY-D1601
CAS No.: 98907-26-7
N-Aminofluorescein is a fluorescein hydrazide with spiro form, a highly selective and sensitive fluorescence probe for Cu 2+. N-Aminofluorescein has no selective fluorescence response to other common metal ions, can be used for direct detection of Cu 2+ in biological systems with λex/em=495/516 nm . N-Aminofluorescein can be used to measure the concentration of copper ions in cells .
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1
Pyrene
Pyrene
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1 Cited Publications
Cat. No.: HY-103609
CAS No.: 129-00-0
Purity:  99.72%
Synonyms: Benzo[def]phenanthrene
Pyrene is a polycyclic aromatic hydrocarbon (PAH) composed of four fused benzene rings. It has a distinct aromatic odor, produced by incomplete combustion of organic matter. Pyrene exhibits strong fluorescence, emitting in the blue region of the spectrum, making it useful as a probe for studying molecular interactions in solution and on surfaces. Pyrene is also used as a model compound for the study of PAHs in various environments and biological systems because of its ubiquity in these environments. However, long-term exposure to pyrene has been associated with potential health risks, including carcinogenicity and mutagenicity.
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TOOS
TOOS
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Cat. No.: HY-15932
CAS No.: 82692-93-1
Synonyms: TOOS sodium salt
TOOS (TOOS sodium salt) is a highly water-soluble aniline derivative widely used in diagnostics and biological experiments. TOOS can be combined with 3-methyl-2-benzothiazolinone hydrazone hydrochloride (MBTH) to form a chromogenic system to measure oxidase activity. In the MBTH-TOOS chromogenic system, MBTH is catalytically oxidized to produce (-NH) free radicals, which react with TOOS to form colorless compounds. Furthermore, the colorless compound undergoes a disproportionation reaction to produce a blue-violet quinoid compound .
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Pigment Yellow 139
Pigment Yellow 139
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Cat. No.: HY-D0284
CAS No.: 36888-99-0
Pigment Yellow 139 is a biological dye and indicator. Pigment Yellow 139 is an organic pigment and an additive for color filters of liquid crystal displays. When formulated in a dye-pigment hybrid system, Pigment Yellow 139 can form color filters with specific chromaticity coordinates, brightness, contrast, and average particle size .
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Heneicosanoic acid
Heneicosanoic acid
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Cat. No.: HY-121447
CAS No.: 2363-71-5
Purity:  ≥98.0%
Category:  

Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

Heneicosanoic acid is an odd-chain saturated fatty acid widely present in human milk, fish, seeds, and cerebrosides in the cell membranes of the nervous system. Heneicosanoic acid can form Langmuir monolayers and is often used as a model to study lipid self-assembly and disassembly processes in biological membranes and drug delivery systems. In the low-temperature L'2 and CS crystalline phases, Heneicosanoic acid undergoes local oscillations, which in turn drive the spontaneous formation and expulsion of micelles and vesicles .
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MOPSO
MOPSO
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Cat. No.: HY-101850
CAS No.: 68399-77-9
Purity:  99.66%
MOPSO is a zwitterionic biological buffer with a functional pH range of 6.2 to 7.6. MOPSO serves as a component of buffered charcoal yeast extract medium; it can also be used to prepare a MOPSO-ethanol buffer system for the immobilization of urine-derived cells .
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