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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
43 Results for "
bottom ash
" in MedChemExpress (MCE) Product Catalog:
Products (43)
43 Results for "bottom ash" in MCE Product Catalog:
7
Category:
Flavones Metabolic Disease Plants Brassicaceae Extract Phyllanthus Flavonoids Phenols Polyphenols Disease Research Fields Coronopus didymus Euphorbiaceae Extract
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5
Category:
Monophenols Coumarins Phenols Phenylpropanoids Plants Other Families Extract Disease Research Fields Cancer
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5
5 Cited Publications
Cat. No.: HY-W166297
CAS No.: 66778-17-4
Esculin sesquihydrate, a fluorescent coumarin glucoside, is an active ingredient of ash bark. Esculin sesquihydrate ameliorates cognitive impairment in experimental diabetic nephropathy (DN), and exerts anti?oxidative stress and anti?inflammatory effects, via the MAPK signaling pathway .
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2 Cited Publications
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AS-99 TFA is a first-in-class, potent and selective ASH1L histone methyltransferase inhibitor (IC50= 0.79 μM, Kd= 0.89 μM) with anti-leukemic activity. AS-99 TFA blocks cell proliferation, induces apoptosis and differentiation, downregulates MLL fusion target genes, and reduces the leukemia burden in vivo .
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2 Cited Publications
Cat. No.: HY-141429
CAS No.: 2323623-93-2
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AS-99 is a first-in-class, potent and selective ASH1L histone methyltransferase inhibitor (IC50= 0.79 µM, Kd= 0.89 µM) with anti-leukemic activity. AS-99 blocks cell proliferation, induces apoptosis and differentiation, downregulates MLL fusion target genes, and reduces the leukemia burden in vivo .
Cat. No.: HY-E0225
The 0.5 mL SBS Rack is a 96-well biobank storage rack suitable for -80°C environments. It can hold 0.5 mL externally threaded cryogenic vials with 2D codes on the bottom, and supports automated sample tracking, detection, and laboratory information system integration. The 0.5 mL SBS Rack can be used with camera-based reading devices to scan and log biobank vials with 2D codes into databases, enabling rapid identification of aliquoted samples .
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AS-85 is a potent ASH1L histone methyltransferase inhibitor (IC50=0.6 μM) with anti-leukemic activity. AS-85 strongly binds to the ASH1L SET domain, with the Kd value of 0.78 μM .
Synonyms: SEW04784
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SEW84 is an inhibitor of Aha1-stimulated Hsp90 (ASH) ATPase activity. SEW84 inhibits Aha1-stimulated Hsp90 (ASH) activity with an IC50 value of 0.3 μM. SEW84 can be used in the study of protein deposition diseases .
Cat. No.: HY-121471R
CAS No.: 491-71-4
Cat. No.: HY-170494
CAS No.: 3096805-79-4
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AS-254s is the inhibitor for absent, small, or homeotic-like 1 protein (ASH1L) with an IC50 of 94 nM (FP assay). AS-254s exhibits antiproliferative activity against MLL1-rearranged leukemic cells with GI50 <1 μM. AS-254s induces the differentiation of MLL1-r leukemic cell .
Cat. No.: HY-16138
CAS No.: 936221-33-9
Synonyms: CG-200745
Ivaltinostat (CG-200745) is an orally active, potent pan-HDAC inhibitor which has the hydroxamic acid moiety to bind zinc at the bottom of catalytic pocket. Ivaltinostat inhibits deacetylation of histone H3 and tubulin. Ivaltinostat induces the accumulation of p53, promotes p53-dependent transactivation, and enhances the expression of MDM2 and p21 (Waf1/Cip1) proteins. Ivaltinostat enhances the sensitivity of Gemcitabine-resistant cells to Gemcitabine (HY-16138) and 5-Fluorouracil (5-FU; HY-90006). Ivaltinostat induces apoptosis and has anti-tumour effects .
Cat. No.: HY-16138A
CAS No.: 3078712-42-9
Synonyms: CG-200745 formic
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Ivaltinostat (CG-200745) formic is an orally active, potent pan-HDAC inhibitor which has the hydroxamic acid moiety to bind zinc at the bottom of catalytic pocket. Ivaltinostat formic inhibits deacetylation of histone H3 and tubulin. Ivaltinostat formic induces the accumulation of p53, promotes p53-dependent transactivation, and enhances the expression of MDM2 and p21 (Waf1/Cip1) proteins. Ivaltinostat formic enhances the sensitivity of Gemcitabine-resistant cells to Gemcitabine (HY-16138) and 5-Fluorouracil (5-FU; HY-90006). Ivaltinostat formic induces apoptosis and has anti-tumour effects .
Cat. No.: HY-W111589F
CAS No.: 68855-54-9
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Cat. No.: HY-16521
CAS No.: 800408-39-3
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VX-166, a pan caspase inhibitor, can be used for the research of Non- Alcoholic Fatty Liver Disease (NAFLD), nonalcoholic steatohepatitis (NASH), alcoholic steatohepatitis (ASH), and other diseases involving fibrosis, steatosis, or inflammation of the liver .
Cat. No.: HY-141429C
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AS-99 is a first-in-class, potent, and selective ASH1L histone methyltransferase inhibitor (IC50= 0.79 μM, Kd= 0.89 μM) with anti-leukemic activity. AS-99 blocks cell proliferation, induces apoptosis and differentiation, downregulates MLL fusion target genes, and reduces the leukemia burden in vivo .
Cat. No.: HY-W016174S
CAS No.: 180802-01-1
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Diphenyl sulfide-d1 is the d1-labeled Diphenyl sulfide (HY-W016174). Diphenyl sulfide is an additive for organic photovoltaic devices. Diphenyl sulfide modulates vertical composition distribution of PTB7-Th:PC71BM photoactive layers, promoting enrichment of PTB7-Th at the upper surface and PC71BM at the bottom. Diphenyl sulfide promotes ordered molecular packing and crystallinity of PTB7-Th:PC71BM photoactive layers, including more compact π−π stacking of PTB7-Th. Diphenyl sulfide improves exciton dissociation, charge transport, and charge collection in PTB7-Th:PC71BM-based inverted polymer solar cells. Diphenyl sulfide acts as a solvent additive to improve the photovoltaic performance of inverted organic photovoltaic devices .
Cat. No.: HY-RS01087
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ASH1L Human Pre-designed siRNA Set A contains three designed siRNAs for ASH1L gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS01088
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ASH2L Human Pre-designed siRNA Set A contains three designed siRNAs for ASH2L gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
