202

202 Publications Verification

Target:

Research Areas:

Infection Neurological Disease Inflammation/Immunology Cancer

Doxycycline, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor . Doxycycline shows antibacterial activity and anti-cancer cell proliferation activity .

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202

Doxycycline hyclate

202 Publications Verification

Cat. No.: HY-N0565B

CAS No.: 24390-14-5

Synonyms: Doxycycline hydrochloride hemiethanolate hemihydrate; WC2031

Target:

Antibiotic MMP Bacterial Parasite

Research Areas:

Infection Neurological Disease Inflammation/Immunology Cancer

Doxycycline hyclate, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor. Doxycycline hyclate shows antibacterial activity and anti-cancer cell proliferation activity. Doxycycline hyclate can be used to construct gene expression regulation models .

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202

Doxycycline hydrochloride

202 Publications Verification

Cat. No.: HY-N0565A

CAS No.: 10592-13-9

Target:

MMP Bacterial Antibiotic Parasite

Research Areas:

Infection Neurological Disease Inflammation/Immunology Cancer

Doxycycline hydrochloride, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor . Doxycycline hydrochloride shows antibacterial activity and anti-cancer cell proliferation activity. Doxycycline hydrochloride can be used to construct gene expression regulation models .

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163

Mirdametinib

163 Cited Publications

Cat. No.: HY-10254

CAS No.: 391210-10-9

Purity: 99.95%

Synonyms: PD0325901; PD325901

Target:

MEK Autophagy Apoptosis

Research Areas:

Cancer

Mirdametinib (PD0325901) is an orally active, selective and non-ATP-competitive MEK inhibitor with an IC₅₀ of 0.33 nM. Mirdametinib exhibits a K_i ^app of 1 nM against activated MEK1 and MEK2. Mirdametinib suppresses the expression of p-ERK1/2 and induces apoptosis. Mirdametinib has anti-cancer activity for a broad spectrum of human tumor xenografts .

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30

Hesperetin

30 Cited Publications

Cat. No.: HY-N0168

CAS No.: 520-33-2

Category:

Flavonoids Neurological Disease Sunscreen Flavonones Cosmetic Research Plants Other Families Extract Disease Research Fields Cancer

Target:

p38 MAPK Autophagy Apoptosis Reactive Oxygen Species (ROS) NF-κB Bcl-2 Family

Hesperetin is a natural flavanone that can be found in citrus, and acts as a potent and orally active broad-spectrum inhibitor against human UGT activity. Hesperetin induces apoptosis via p38 MAPK activation. Hesperetin displays a range of bioactivities including antioxidant, anti-inflammatory, and anti-cancer. Hesperetin is found to induce cell-cycle arrest at G2/M phase. Hesperetin can reduce Bcl-2 and enhance BaxM. Hesperetin induces apoptosis through inhibiting NF-κB receptor .

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19

Nelfinavir

19 Cited Publications

Cat. No.: HY-15287

CAS No.: 159989-64-7

Purity: 98.74%

Synonyms: AG1341

Target:

HIV Protease HIV

Research Areas:

Infection Cancer

Nelfinavir (AG-1341) is a potent and orally bioavailable HIV-1 protease inhibitor (K_i=2 nM) for HIV infection. Nelfinavir is a broad-spectrum, anticancer agent .

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