51 Results for "

carboxyl terminal groups

" in MedChemExpress (MCE) Product Catalog:
Products (51)

51 Results for "carboxyl terminal groups" in MCE Product Catalog:

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1 Cited Publications
Cat. No.: HY-142978
CAS No.: 156543-00-9
Synonyms: DSPE-mPEG2000
Target:  

Liposome

Research Areas:  

Others

18:0 mPEG2000 PE (DSPE-mPEG2000) ammonium is a kind of amphiphilic polymer material. 18:0 mPEG2000 PE ammonium combines hydrophobic lipids (18:0 stearic acid chain) with hydrophilic polyethylene glycol (2 kDa) chains to form amphiphilic molecules, which are used to construct stable liposomes/nanoparticles, thereby enhancing drug delivery, prolonging circulation time, and achieving targeted effects through its functional terminal groups (usually biotin or carboxyl groups). 18:0 mPEG2000 PE ammonium can be used for the research of nanoprobes and drug delivery .
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1 Cited Publications
Cat. No.: HY-148140
CAS No.: 9041-35-4
Research Areas:  

Others

Cross-linked dextran G 25 is a cross-linked dextran gel chromatography medium that possesses multiple separation activities, including molecular sieve effects, weak anion exchange, and aromatic adsorption. Cross-linked dextran G 25 weakly exchanges cations through immobilized terminal carboxyl groups and repels anions at low ionic strength. Cross-linked dextran G 25 is used for the fractionation of low molecular weight solutes, including peptides, amino acids, nucleotide sugar derivatives, and aromatic compounds .
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1
1 Cited Publications
Cat. No.: HY-158089
Purity:  ≥95.0%
Research Areas:  

Others

PLGA-COOH (MW 80000) (LA/GA 50:50) is a copolymer composed of lactic acid (LA)-glycolic acid (GA) at a molar ratio of 50:50 and a terminal carboxyl group. PLGA-COOH (MW 80000) (LA/GA 50:50) is used in compound delivery systems due to its biocompatibility and biodegradability .
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Cat. No.: HY-W1048558A
Synonyms: mPEG2000-COOH
mPEG2000-CM (mPEG2000-COOH) is a carboxyl-terminated monomethoxy polyethylene glycol. mPEG2000-CM bears a reactive carboxyl group (-COOH) at its structural terminal site, which can form stable amide bonds with amino groups and ester bonds with hydroxyl groups. mPEG2000-CM binds to PCA-g-PCL copolymers via electrostatic interaction to form polyion complex micelles with a hydrophilic PEG surface, which enhances the stability of micelles in aqueous media. mPEG2000-CM can be used for drug delivery .
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Cat. No.: HY-144013H
CAS No.: 474922-77-5
Purity:  99%
Synonyms: DSPE-mPEG5000 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] ammonium
Target:  

Liposome

Research Areas:  

Cancer

18:0 mPEG5000 PE (DSPE-mPEG5000) ammonium is a kind of amphiphilic polymer material. 18:0 mPEG5000 PE ammonium combines hydrophobic lipids (18:0 stearic acid chain) with hydrophilic polyethylene glycol (5 kDa) chains to form amphiphilic molecules, which are used to construct stable liposomes/nanoparticles, thereby enhancing drug delivery, prolonging circulation time, and achieving targeted effects through its functional terminal groups (usually biotin or carboxyl groups). 18:0 mPEG5000 PE ammonium can be used for the research of nanoprobes and drug delivery .
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Cat. No.: HY-P5481
CAS No.: 1807943-24-3
Target:  

Inhibitory Antibodies

Research Areas:  

Others

DABCYL-LPETG-EDANS is a biological active peptide. (This 5-amino acid peptide is a sortase substrate, C-terminal sorting signal. Sortase cleaves surface proteins at the LPXTG motif and catalyzes the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges. Sortases are a family of Gram-positive transpeptidases responsible for anchoring surface protein virulence factors to the peptidoglycan cell wall layer. Cleavage of this FRET substrate by sortase reveals the fluorescent signal, Abs/Em = 340/490 nm.)
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Cat. No.: HY-W1048549A
Synonyms: HOOC-PEG2000-Thiol
HOOC-PEG2000-SH (HOOC-PEG2000-Thiol) is a reactive thiol PEG derivative with a terminal carboxyl group. The carboxyl group can react with amine or hydroxyl groups to form a stable amide bond or an unstable ester bond. The PEG linkage between the thiol and carboxyl groups has good water solubility, flexible linker distance and higher stability .
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Cat. No.: HY-W1048918A
Synonyms: mPEG5000-COOH
mPEG5000-CM (mPEG5000-COOH) has a reactive carboxyl group (-COOH) attached to the terminal site of the structure, which can form a stable amide bond with the amino group or an ester bond with the hydroxyl group. mPEG5000-CM can be used for drug delivery .
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Cat. No.: HY-W009229
CAS No.: 13726-84-6
Research Areas:  

Others

Boc-Glu (OtBu)-OH is a glutamic acid-derived protected amino acid with its N-terminal amino group protected by tert-butyloxycarbonyl (Boc) and side-chain carboxyl group protected by tert-butyl ester (OtBu), serving as an orthogonally protected building block for polypeptide synthesis. Boc-Glu (OtBu)-OH is applicable to research on the synthesis of peptide compounds .
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Cat. No.: HY-148140A
CAS No.: 9041-35-4
Research Areas:  

Others

Cross-linked dextran G 25, coarse is a cross-linked dextran gel chromatography coarse (average particle size D50 = 200-250 μm) that possesses multiple separation activities, including molecular sieve effects, weak anion exchange, and aromatic adsorption. Cross-linked dextran G 25, coarse weakly exchanges cations through immobilized terminal carboxyl groups and repels anions at low ionic strength. Cross-linked dextran G 25, coarse is used for the fractionation of low molecular weight solutes, including peptides, amino acids, nucleotide sugar derivatives, and aromatic compounds .
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Cat. No.: HY-148140B
CAS No.: 9041-35-4
Research Areas:  

Others

Cross-linked dextran G 25, medium is a cross-linked dextran gel chromatography medium (average particle size D50 = 120-140 μm) that possesses multiple separation activities, including molecular sieve effects, weak anion exchange, and aromatic adsorption. Cross-linked dextran G 25, medium weakly exchanges cations through immobilized terminal carboxyl groups and repels anions at low ionic strength. Cross-linked dextran G 25, medium is used for the fractionation of low molecular weight solutes, including peptides, amino acids, nucleotide sugar derivatives, and aromatic compounds .
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Cat. No.: HY-148140C
CAS No.: 9041-35-4
Research Areas:  

Others

Cross-linked dextran G 25, fine is a cross-linked dextran gel chromatography fine (average particle size D50 = 70-90 μm) that possesses multiple separation activities, including molecular sieve effects, weak anion exchange, and aromatic adsorption. Cross-linked dextran G 25, fine weakly exchanges cations through immobilized terminal carboxyl groups and repels anions at low ionic strength. Cross-linked dextran G 25, fine is used for the fractionation of low molecular weight solutes, including peptides, amino acids, nucleotide sugar derivatives, and aromatic compounds .
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Cat. No.: HY-136772
CAS No.: 2380273-67-4
Purity:  97.05%
Research Areas:  

Others

Pomalidomide-PEG1-NH2 hydrochloride is a crosslinker-E3 ligase ligand conjugate, consisting of an E3 ligase ligand pomalidomide and a PEGylated crosslinker with terminal amine for reactivity with a carboxyl group on the target ligand .
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Cat. No.: HY-W1048549C
Synonyms: HOOC-PEG5000-Thiol
HOOC-PEG5000-SH (HOOC-PEG5000-Thiol) is a reactive thiol PEG derivative with a terminal carboxyl group. The carboxyl group can react with amine or hydroxyl groups to form a stable amide bond or an unstable ester bond. The PEG linkage between the thiol and carboxyl groups has good water solubility, flexible linker distance and higher stability .
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Cat. No.: HY-W1048549E
Synonyms: HOOC-PEG20000-Thiol
HOOC-PEG20000-SH (HOOC-PEG20000-Thiol) is a reactive thiol PEG derivative with a terminal carboxyl group. The carboxyl group can react with amine or hydroxyl groups to form a stable amide bond or an unstable ester bond. The PEG linkage between the thiol and carboxyl groups has good water solubility, flexible linker distance and higher stability .
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Cat. No.: HY-W1048918
Synonyms: mPEG1000-COOH
Research Areas:  

Others

mPEG1000-CM is a methoxypolyethylene glycol derivative with a carboxyl terminal group and precursor for synthesizing ROS-sensitive amphiphilic polymers for transdermal drug delivery systems. mPEG1000-CM can be used for the research of psoriasis .
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Cat. No.: HY-P11353
CAS No.: 117138-19-9
Research Areas:  

Infection Cancer

HA2 peptide is a potent pH-responsive fusion peptide derived from hemagglutinin (HA), corresponding to the N-terminal fusion peptide domain consisting of 23 amino acid residues of HIV-1 gp41 envelope glycoprotein. HA2 peptide adopts a random coil structure under physiological pH conditions; in acidic endosomes, protonation of carboxyl groups reduces negative charge, inducing a transition to an α-helical conformation that can fuse with and destabilize the endosomal membrane. After binding to membranes, the N-terminal and middle regions of HA2 peptide mainly adopt a β-strand conformation, while the C-terminal region remains unstructured. HA2 peptide induces lipid mixing and promotes aqueous content leakage from large unilamellar vesicles whose lipid composition matches that of HIV-1 viruses and target T cells. HA2 peptide is anionic and can bind to cationic peptides to achieve siRNA condensation. HA2 peptide can be used in studies related to cancer and human immunodeficiency virus (HIV) infection .
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Cat. No.: HY-W1048549B
Synonyms: HOOC-PEG3400-Thiol
HOOC-PEG3400-SH (HOOC-PEG3400-Thiol) is a reactive thiol PEG derivative with a terminal carboxyl group. The carboxyl group can react with amine or hydroxyl groups to form a stable amide bond or an unstable ester bond. The PEG linkage between the thiol and carboxyl groups has good water solubility, flexible linker distance and higher stability .
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Cat. No.: HY-W1048549D
Synonyms: HOOC-PEG10000-Thiol
HOOC-PEG10000-SH (HOOC-PEG10000-Thiol) is a reactive thiol PEG derivative with a terminal carboxyl group. The carboxyl group can react with amine or hydroxyl groups to form a stable amide bond or an unstable ester bond. The PEG linkage between the thiol and carboxyl groups has good water solubility, flexible linker distance and higher stability .
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Cat. No.: HY-W1048549H
Synonyms: HOOC-PEG1000-Thiol
HOOC-PEG1000-SH (HOOC-PEG1000-Thiol) is a reactive thiol PEG derivative with a terminal carboxyl group. The carboxyl group can react with amine or hydroxyl groups to form a stable amide bond or an unstable ester bond. The reaction of the carboxyl group allows the amine or hydroxyl group to be converted into a free thiol with a linear PEG linkage. The generated thiol group can be used to modify the surface of gold nanoparticles or participate in other PEGylation reactions. The PEG linkage between the thiol and carboxyl groups has good water solubility, flexible linker distance and higher stability .
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