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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
carboxyl-functionalized
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "carboxyl-functionalized" in MCE Product Catalog:
4
4 Cited Publications
Cat. No.: HY-K0225
MCE Carboxyl Magnetic beads (200 nm, 10 mg/mL) are characterized by superparamagnetism, fast magnetic response, abundant carboxyl functional groups, monodispersity, and submicron scale particle size. Biological ligands (proteins, peptides, oligonucleotides, drug molecules, etc.) can be covalently coupled to the surface of microspheres under the action of special chemical reagents (such as EDC).
Cat. No.: HY-114118S1
Target:
Isotope-Labeled Compounds GLP Receptor Insulin Receptor α-synuclein Apoptosis p38 MAPK Autophagy Bcl-2 Family
Research Areas:
Cat. No.: HY-155455
CAS No.: 2892008-07-8
Target:
Research Areas:
Hapten Dca is an immunizing hapten. Hapten Dca is activated by a solution of N, N′-disuccinimidyl carbonate. Hapten Dca with a carboxyl functional group is conjugated to proteins .
Cat. No.: HY-D3416
Synonyms: TAMRA-2,4-dinitroaniline
Target:
Research Areas:
TMR-DN (TAMRA-2,4-dinitroaniline) is a fluorescent probe for RNA imaging that consists of a covalently coupled fluorophore (5-carboxy tetramethylrhodamine (TMR)) and quencher (dinitroaniline (DN)). The Kd value of TMR-DN with SRB-2 is 35 nM, and its Kd value with RhoBAST is approximately 30 nM. TMR-DN has a contact quenching function and forms a non-fluorescent intramolecular ground-state dimer in the free state; the excitation/emission wavelengths of the free probe are Ex/Em = 557/579 nm, those of the complex formed by binding to SRB-2 are Ex/Em = 561/587 nm, and those of the probe bound to the DNB aptamer are Ex/Em = 555/582 nm. TMR-DN reduces non-specific binding to genomic nucleic acids via negatively charged carboxyl-functionalized aromatic rings. Fluorescence dequenching occurs when TMR-DN specifically binds to SRB-2, RhoBAST or the DNB aptamer, among which the binding of RhoBAST requires Mg 2+ for proper folding .
Cat. No.: HY-184640
Carboxylated magnetic microspheres are magnetic microspheres with abundant carboxyl functional groups on their surface. They are usually composed of superparamagnetic materials (such as Fe3O4) and polymer materials, with polystyrene microspheres as the core.
Cat. No.: HY-184627
The core material of carboxylated dextran-modified iron oxide nanoparticles is iron oxide (Fe3O4), which possesses superparamagnetic properties, making it suitable for applications requiring magnetic field response. The surface is coated with carboxylated dextran, a modification that increases the nanoparticles' water solubility and biocompatibility, while also providing carboxyl functional groups, facilitating further chemical modification and biomolecular coupling.
Cat. No.: HY-184637
DMSA Coated Fe2O3 Nanoparticles (Carboxylated ferric oxide nanoparticles) are magnetic nanomaterials with carboxyl (-COOH) groups modified on their surface. These materials typically consist of ferric oxide (Fe2O3) nanoparticles as a core, with carboxyl functional groups introduced to the surface through chemical modification. The carboxylation of the nanoparticle surface increases its negative surface charge, contributing to improved solubility and stability in water. Carboxylated ferric oxide nanoparticles exhibit good biocompatibility, making them suitable for biomedical applications.
Cat. No.: HY-184639
Carboxylated magnetic microspheres (low nonspecificity) are functionalized nano- or micron-sized magnetic particles with abundant carboxyl functional groups on their surface. Special chemical treatments reduce the likelihood of nonspecific adsorption. This 1μm carboxylated magnetic microsphere features a core-shell structure: a PS core, an outer layer of iron oxide (Fe3O4), and an outermost encapsulation layer. The carboxyl groups are obtained through polymer modification. Exhibiting low nonspecific adsorption, these microspheres can covalently couple with bioligands such as peptides, proteins, antibodies, and oligonucleotides using specific chemical reagents (e.g., EDC), making them particularly suitable for cell sorting, affinity chromatography, and immunoassay.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
