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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
cardiac volume
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "cardiac volume" in MCE Product Catalog:
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2-(Methylthio)benzothiazole is a derivative of 2-Mercaptobenzothiazole (HY-W017113). 2-(Methylthio)benzothiazole reduces heart rate, causes pericardial edema and deformity, delays cardiac maturation, decreases stroke volume and cardiac output, and leads to vascular structural defects in zebrafish larvae .
Cat. No.: HY-105011A
CAS No.: 161800-08-4
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YM-358 hydrate potassium is an orally active angiotensin II type 1 (AT1)-receptor antagonist. YM-358 hydrate potassium can decrease cardiac volume overload. YM-358 hydrate potassium can be used for the research of cardiovascular disease, such as hypertension .
Cat. No.: HY-P1428A
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Synonyms: (-)-Metaraminol; (-)-erythro-Metaraminol; (-)-m-Hydroxynorephedrine
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Metaraminol ((-)-Metaraminol) is a sympathomimetic compound with activity that acts primarily at alpha-1 adrenergic receptors. Metaraminol is used to inhibit hypotension due to vasodilation, particularly in critically ill patients who do not respond well to volume resuscitation. Metaraminol may also be used as an adjunct to help improve cardiac contractility. The use of metaraminol may be supported by less evidence, but its effectiveness in specific situations remains of interest .
Cat. No.: HY-134043
CAS No.: 16289-13-7
Synonyms: Chlorthalidone EP Impurity G
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Chlorthalidone Impurity G (Chlorthalidone EP Impurity G) is a potential impurity found in commercial preparations of chlorthalidone with moderate antihypertensive effects. Chlorthalidone is a thiazide diuretic that inhibits the Na+/Cl- cotransporter in the distal tubule of the kidney, thereby preventing sodium and chloride reabsorption, resulting in decreased plasma volume and cardiac output. It also inhibits carbonic anhydrase (CA), including isoenzymes CAVB, VII, IX, XII, and XIII (Kis=2.8-23 nM) and to a lesser extent CAI, CAII, IV, VA, and VI (Ki=138-1,347 nM), mediating vasodilatory activity.
Cat. No.: HY-149796
CAS No.: 39832-48-9
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Tazolol is a specific β-adrenergic antagonist (IC50: 700 nM for (-) isoproterenol-elicited accumulation of cyclic AMP in rat cortical slices). Tazolol produces a significant and sustained increase in cardiac output and stroke volume. Tazolol can be used in the research of heart failure .
Cat. No.: HY-182252
CAS No.: 1426899-28-6
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SAR296968 is a Na +/Ca 2+ exchanger (NCX) subtype inhibitor with an IC50 value of 74 nM against hNCX1. SAR296968 inhibits both forward and reverse modes of NCX current. SAR296968 enhances cardiac contractility and stroke volume. SAR296968 exerts antiarrhythmic effects. SAR296968 is applicable to research related to heart failure .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
