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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
28 Results for "
carp
" in MedChemExpress (MCE) Product Catalog:
Products (28)
28 Results for "carp" in MCE Product Catalog:
1
Moroxydine (ABOB) hydrochloride is a broad-spectrum agent with multi-antiviral activities against DNA and RNA viruses, including influenza virus, herpes simplex, varicella zoster, measles, mumps disease, hepatitis C virus, etc. Moroxydine hydrochloride exhibits excellent antiviral activity and shows low cytotoxicity to cells infected by dsRNA viruses (grass carp reovirus, GCRV) and large DNA viruses (giant salamander iridovirus, GSIV). Moroxydine hydrochloride blocks the GCRV-induced cytopathic effects and eliminates nucleocapsids in ctenopharyngodon idella kidney (CIK) cells to keep the normal morphological structure. Moroxydine hydrochloride significantly inhibits the apoptosis, the caspase 3 activity, Bax expression and down-regulates Bcl-2 levels .
Cat. No.: HY-B0819
CAS No.: 14816-18-3
Target:
Insecticide Cholinesterase (ChE) Cytochrome P450 Autophagy Reactive Oxygen Species (ROS) Apoptosis Bcl-2 Family Caspase COX Keap1-Nrf2 TNF Receptor Interleukin Related Bacterial
Research Areas:
Phoxim is an organophosphorus pesticide and an orally active inhibitor of cholinesterase and CYP3A, which induces neurotoxicity in Caenorhabditis elegans and causes nephrotoxicity characterized by glomerular atrophy and interstitial fibrosis. Phoxim induces inhibition of the autophagy pathway. Phoxim induces dopaminergic neuron degeneration and exacerbates Aβ-induced paralysis. Phoxim damages enterocytes and disrupts intestinal barrier integrity. Phoxim induces ROS accumulation. Phoxim induces mitochondrial apoptosis, involving upregulation of Bad, Bax, caspase-3, and caspase-9 and downregulation of Bcl-2. Phoxim inhibits mitochondrial functional enzymes (COX, Ca 2+-Mg 2+-ATPase, SDH). Phoxim upregulates Nrf2 mRNA expression in the jejunal mucosa. Phoxim increases TNF-α and decreases IL-6 and IL-8 in the intestinal mucosa. Phoxim alters gut microbial composition by increasing total bacteria and Escherichia coli and reducing Lactobacillus. Phoxim enhances energy metabolism in silver carp by upregulating key glycolytic and gluconeogenic enzymes. Phoxim is used in research on neurodegenerative diseases, nephrotoxicity, intestinal oxidative stress and barrier dysfunction, and bacterial sepsis .
CFM-4 is a potent small molecular antagonist of CARP-1/APC-2 binding. CFM-4 prevents CARP-1 binding with APC-2, causes G2M cell cycle arrest, and induces apoptosis with an IC50 range of 10-15 μM. CFM-4 also suppresses growth of drug-resistant human breast cancer cells .
Cat. No.: HY-119635
CAS No.: 54632-04-1
Category:
Dryopteridaceae Extract Plant Dryopteris fragrans (L.) Schott Extract Terpenoids Sesquiterpenes
Target:
Cat. No.: HY-W016937
CAS No.: 3731-59-7
Synonyms: ABOB
Target:
Research Areas:
Moroxydine (ABOB) is a broad-spectrum agent with multi-antiviral activities against DNA and RNA viruses, including influenza virus, herpes simplex, varicella zoster, measles, mumps disease, hepatitis C virus, etc. Moroxydine exhibits excellent antiviral activity and shows low cytotoxicity to cells infected by dsRNA viruses (grass carp reovirus, GCRV) and large DNA viruses (giant salamander iridovirus, GSIV). Moroxydine blocks the GCRV-induced cytopathic effects and eliminates nucleocapsids in ctenopharyngodon idella kidney (CIK) cells to keep the normal morphological structure. Moroxydine significantly inhibits the apoptosis, the caspase 3 activity, Bax expression and down-regulates Bcl-2 levels [1][2][3].
Cat. No.: HY-RS01775
Target:
Research Areas:
CA8 Human Pre-designed siRNA Set A contains three designed siRNAs for CA8 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS26261
Target:
Research Areas:
Ankrd1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ankrd1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS01764
Target:
Research Areas:
CA11 Human Pre-designed siRNA Set A contains three designed siRNAs for CA11 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS00712
Target:
Research Areas:
ANKRD1 Human Pre-designed siRNA Set A contains three designed siRNAs for ANKRD1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS08453
Target:
Research Areas:
MINDY3 Human Pre-designed siRNA Set A contains three designed siRNAs for MINDY3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Target:
Research Areas:
Bromocyclen is a pesticide found in the muscle tissue of rainbow trout from Danish fisheries and in three species of fish (grill, crucian carp and pike) from the River Stell in northern Germany. High concentrations were detected ranging from 0.09 to 1.23 mg/kg fat .
Synonyms: SD 2774 (Standard); ENT 23393 (Standard); Alugan (Standard)
Target:
Research Areas:
Bromocyclen (Standard) is the analytical standard of Bromocyclen. This product is intended for research and analytical applications. Bromocyclen is a pesticide found in the muscle tissue of rainbow trout from Danish fisheries and in three species of fish (grill, crucian carp and pike) from the River Stell in northern Germany. High concentrations were detected ranging from 0.09 to 1.23 mg/kg fat .
Cat. No.: HY-B0420AR
CAS No.: 3160-91-6
Synonyms: ABOB hydrochloride (Standard)
Research Areas:
Moroxydine (ABOB) hydrochloride (Standard) is the analytical standard of Moroxydine (ABOB) hydrochloride (HY-B0420A). Moroxydine (ABOB) hydrochloride is a broad-spectrum agent with multi-antiviral activities against DNA and RNA viruses, including influenza virus, herpes simplex, varicella zoster, measles, mumps disease, hepatitis C virus, etc. Moroxydine hydrochloride exhibits excellent antiviral activity and shows low cytotoxicity to cells infected by dsRNA viruses (grass carp reovirus, GCRV) and large DNA viruses (giant salamander iridovirus, GSIV). Moroxydine hydrochloride blocks the GCRV-induced cytopathic effects and eliminates nucleocapsids in ctenopharyngodon idella kidney (CIK) cells to keep the normal morphological structure. Moroxydine hydrochloride significantly inhibits the apoptosis, the caspase 3 activity, Bax expression and down-regulates Bcl-2 levels.
Cat. No.: HY-W713297
CAS No.: 2469734-82-3
Synonyms: ABOB hydrochloride-d8
Cat. No.: HY-W758414
Phoxim-d5 (phenyl-d5) (mixture of isomers) is the deuterated-labeled Phoxim (HY-B0819). Phoxim is an organophosphorus pesticide and an orally active inhibitor of cholinesterase and CYP3A, which induces neurotoxicity in Caenorhabditis elegans and causes nephrotoxicity characterized by glomerular atrophy and interstitial fibrosis. Phoxim induces inhibition of the autophagy pathway. Phoxim induces dopaminergic neuron degeneration and exacerbates Aβ-induced paralysis. Phoxim damages enterocytes and disrupts intestinal barrier integrity. Phoxim induces ROS accumulation. Phoxim induces mitochondrial apoptosis, involving upregulation of Bad, Bax, caspase-3, and caspase-9 and downregulation of Bcl-2. Phoxim inhibits mitochondrial functional enzymes (COX, Ca 2+-Mg 2+-ATPase, SDH). Phoxim upregulates Nrf2 mRNA expression in the jejunal mucosa. Phoxim increases TNF-α and decreases IL-6 and IL-8 in the intestinal mucosa. Phoxim alters gut microbial composition by increasing total bacteria and Escherichia coli and reducing Lactobacillus. Phoxim enhances energy metabolism in silver carp by upregulating key glycolytic and gluconeogenic enzymes. Phoxim is used in research on neurodegenerative diseases, nephrotoxicity, intestinal oxidative stress and barrier dysfunction, and bacterial sepsis .
Cat. No.: HY-P76765
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CA8; Carbonic Anhydrase-Related Protein; Prev. CALS; Carbonic Anhydrase-Like Sequence; CA-VIII; Carbonate Dehydratase; carp; CA-Related Protein; Carbonic Anhydrase VIII; CAMRQ3; CA-RP; SCAR34; Carbonic Anhydrase 8 (Inactive); Carbonic Anhydrase 8
Species:
Mouse
Source:
E. coli
Cat. No.: HY-P7723
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CA8; Carbonic Anhydrase-Related Protein; Prev. CALS; Carbonic Anhydrase-Like Sequence; CA-VIII; Carbonate Dehydratase; carp; CA-Related Protein; Carbonic Anhydrase VIII; CAMRQ3; CA-RP; SCAR34; Carbonic Anhydrase 8 (Inactive); Carbonic Anhydrase 8
Species:
Human
Source:
E. coli
Cat. No.: HY-P7729
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CA11; Carbonic Anhydrase 11; Carbonic Anhydrase 11 (Inactive); Carbonic Anhydrase XI; Carbonic Anhydrase-Related Protein 11; CA-RP II; Carbonic Anhydrase-Related Protein 2; carp-2; CA-RP XI; CA-XI; carpX1; carp XI; carp2; CA-RP; Carbonic Anhydrase-Related
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
