Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
cataract formation
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "cataract formation" in MCE Product Catalog:
114
114 Cited Publications
Cat. No.: HY-19696B
CAS No.: 117609-50-4
Synonyms: Tauroursodeoxycholic acid dihydrate; TUDCA dihydrate; UR 906 dihydrate
Cat. No.: HY-112573A
CAS No.: 3863-80-7
Synonyms: Phacolysine sodium
Target:
Research Areas:
Azapentacene (Phacolysine) sodium is an anti-cataract compound. Azapentacene sodium prevents cataract formation in guinea pigs with vitamin C deficiency and delays the progression of congenital cataract in Nakano mice. Azapentacene sodium undergoes reversible one-electron oxidation to form a stable radical cation, undergoes irreversible secondary oxidation to form a hydrolyzable unstable dication, and can also be oxidized by thallium (III) trifluoroacetate in trifluoroacetic acid to generate a detectable radical cation. Azapentacene sodium is used in research related to cataracts, vitamin C deficiency-induced cataracts, and congenital cataracts .
Category:
Cat. No.: HY-185048
Synonyms: IDD-676
Target:
Research Areas:
Lidorestat (IDD-676) is a potent, selective and orally active aldose reductase inhibitor with an IC50 of 5 nM. Lidorestat can be used for chronic diabetes complications. Lidorestat also improves nerve conduction and reduces cataract formation .
Cat. No.: HY-106198R
CAS No.: 245116-90-9
Synonyms: IDD-676 (Standard)
Target:
Research Areas:
Lidorestat (Standard) is the analytical standard of Lidorestat (HY-106198). This product is intended for research and analytical applications. Lidorestat (IDD-676) is a potent, selective and orally active aldose reductase inhibitor with an IC50 of 5 nM. Lidorestat can be used for chronic diabetes complications. Lidorestat also improves nerve conduction and reduces cataract formation .
Cat. No.: HY-165518
CAS No.: 128851-55-8
Target:
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology
M 16287 is an orally active aldose reductase inhibitor, with an IC50 of 0.08 μM in rats and 0.25 μM in cattle. M 16287 improves lens fiber swelling and vacuolization, prevents galactitol accumulation, delays inositol depletion, inhibits glutathione reduction, restores the NADPH/NADP + ratio to normal, and normalizes lens Na + content and Na +/K + ratio. M 16287 prevents galactose-induced cataract formation in rats. M 16287 improves motor nerve conduction velocity in diabetic rats, partially alleviates histopathological changes in the sciatic nerve, and inhibits sorbitol accumulation. M 16287 can be used in studies related to cataracts and diabetic neuropathy .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
