1385

1385 Publications Verification

Target:

Parasite Autophagy SARS-CoV Toll-like Receptor (TLR) HIV Antibiotic

Research Areas:

Infection Inflammation/Immunology Cancer

Chloroquine is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro (EC₅₀=1.13 μM) .

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(-)-Chloroquine

Cat. No.: HY-W614112

CAS No.: 58175-87-4

Target:

Drug Isomer

Research Areas:

Others

(-)-Chloroquine is a chloroquine enantiomer .

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(+)-Chloroquine

Cat. No.: HY-156862

CAS No.: 58175-86-3

Target:

Angiotensin Receptor

Research Areas:

Others

(+)-Chloroquine is a aminoquinoline drug impairs in vitro the terminal glycosylation of angiotensin-converting enzyme 2 (ACE-2) .

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1385

Chloroquine phosphate

1385 Publications Verification

Cat. No.: HY-17589

CAS No.: 50-63-5

Target:

Parasite Autophagy SARS-CoV Toll-like Receptor (TLR) HIV Antibiotic

Research Areas:

Infection Inflammation/Immunology Cancer

Chloroquine phosphate is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine phosphate is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine phosphate is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro (EC₅₀=1.13 μM) .

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1385

Chloroquine dihydrochloride

1385 Publications Verification

Cat. No.: HY-17589B

CAS No.: 3545-67-3

Target:

Parasite Autophagy SARS-CoV Toll-like Receptor (TLR) HIV Antibiotic

Research Areas:

Infection Inflammation/Immunology Cancer

Chloroquine dihydrochloride is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine dihydrochloride is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine dihydrochloride is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro (EC₅₀=1.13 μM) .

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3

Chloroquine (Standard)

3 Cited Publications

Cat. No.: HY-17589AR

CAS No.: 54-05-7

Target:

Reference Standards Parasite Autophagy SARS-CoV Toll-like Receptor (TLR) HIV Antibiotic

Research Areas:

Infection Inflammation/Immunology Cancer

Chloroquine (Standard) is the analytical standard of Chloroquine. This product is intended for research and analytical applications. Chloroquine is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro (EC₅₀=1.13 μM) .

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2

Purvalanol B

2 Cited Publications

Cat. No.: HY-18299

CAS No.: 212844-54-7

Synonyms: NG 95

Target:

CDK Parasite

Research Areas:

Infection Cancer

Purvalanol B (NG 95) is a potent, selective, reversible and ATP-competitive inhibitor CDK, with IC₅₀s of 6 nM, 6 nM, 9 nM, 6 nM for cdc2-cyclin B, CDK2-cyclin A, CDK2-cyclin E and CDK5-p35, respectively. Purvalanol B shows selectivity for CDK over a range of other protein kinases (IC₅₀>1000 nM). Purvalanol B inhibits the growth a chloroquine-resistant strain of P. falciparum .

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2

Desethyl chloroquine diphosphate

2 Cited Publications

Cat. No.: HY-135811A

CAS No.: 247912-76-1

Purity: 99.72%

Target:

Parasite Toll-like Receptor (TLR) Autophagy

Research Areas:

Infection

Desethyl chloroquine diphosphate is a major desethyl metabolite of Chloroquine. Chloroquine diphosphate is an inhibitor of autophagy and toll-like receptors (TLRs). Desethyl chloroquine diphosphate possesses antiplasmodic activity .

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2

Desethyl chloroquine

2 Cited Publications

Cat. No.: HY-135811

CAS No.: 1476-52-4

Target:

Parasite Toll-like Receptor (TLR) Autophagy

Research Areas:

Infection

Desethyl chloroquine is a major desethyl metabolite of Chloroquine. Chloroquine diphosphate is an inhibitor of autophagy and toll-like receptors (TLRs). Desethyl chloroquine possesses antiplasmodic activity .

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