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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
66 Results for "
cholesterol--lowering
" in MedChemExpress (MCE) Product Catalog:
Products (66)
66 Results for "cholesterol--lowering" in MCE Product Catalog:
18
18 Cited Publications
Cat. No.: HY-N0527
CAS No.: 14937-32-7
Synonyms: Penta-O-galloyl-β-D-glucose; 1,2,3,4,6-Pentagalloyl glucose
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2 Cited Publications
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2 Cited Publications
Cat. No.: HY-N0508
CAS No.: 85026-55-7
Category:
Rhodiola rosea Linn. Extract Plant Simple Phenylpropanols Crassulaceae Extract Phenylpropanoids Disease Research Fields Inflammation/Immunology
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Natural Products Plant Other Diseases Euphorbia boetica Extract Disease Research Fields Euphorbiaceae Extract
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Cat. No.: HY-W008226
CAS No.: 480-66-0
Synonyms: 2,4,6-trihydroxyacetophenone; 1-(2,4,6-Trihydroxyphenyl)ethanone
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Zingiberaceae Extract Curcuma comosa Roxb. Extract Metabolic Disease Other Families Extract Infection Plant Ketones, Aldehydes, Acids Phenols Polyphenols Disease Research Fields
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Cat. No.: HY-N9811
CAS No.: 54695-80-6
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Cat. No.: HY-W414588
CAS No.: 50673-97-7
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Colestolone is a 15-ketosterol compound and an orally active inhibitor of HMG-CoA reductase. Colestolone can inhibit the activity of cholesteryl ester transfer protein (CETP) in vitro (IC50 = 660 μM). Colestolone is a cholesterol-lowering agent, and can be used in the research of endocrine and metabolic diseases such as hyperlipidemia .
Cat. No.: HY-NP026
Synonyms: C-phycocyaninfromporphyratenera
Synonyms: Calcium D-glucarate tetrahydrate
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Cat. No.: HY-19513
CAS No.: 852947-39-8
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MB-07344 is a potent thyroid hormone receptor (TR)-β agonist with a Ki of 2.17 nM. MB-07344 has additive cholesterol lowering activity in combination with Atorvastatin (HY-B0589) in rabbits, dogs and monkeys .
Cat. No.: HY-B0589H
CAS No.: 1072903-92-4
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Strontium atorvastatin is a cholesterol-lowering drug with activity in ameliorating cardiovascular disease-related events. Strontium atorvastatin exerts its biological activity by inhibiting HMG-CoA reductase in liver tissue. Strontium atorvastatin is also used to suppress dyslipidemia .
Cat. No.: HY-124064
CAS No.: 128831-46-9
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TMP-153 is an orally active inhibitor of ACAT with an IC50 value of approximately 5-10 nM against hepatic and intestinal ACAT in varicose animals. TMP-153 exhibits cholesterol-lowering effects and can be utilized in the research of atherosclerosis .
Cat. No.: HY-B2097
CAS No.: 138330-18-4
Synonyms: YM 175; Bisphonal
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Incadronate disodium (YM 175) is a bisphosphonate with strong inhibitory activity on bone resorption. Incadronate disodium indirectly stimulates renal 25-hydroxyvitamin D-1-hydroxylase by increasing circulating parathyroid hormone. Incadronate disodium, a cholesterol-lowering agent, is a potent inhibitor of rat liver microsomal squalene synthase (Ki=57 nM). Incadronate disodium inhibits sterol biosynthesis in mouse macrophage J774 cells (IC50=64 μM). Incadronate disodium has the potential for malignant tumors research .
Cat. No.: HY-N0508R
CAS No.: 85026-55-7
Category:
Rhodiola rosea Linn. Extract Plant Simple Phenylpropanols Crassulaceae Extract Phenylpropanoids
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Cat. No.: HY-W353225
CAS No.: 1882-26-4
Synonyms: Pyridinol carbamate
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Pyricarbate (Pyridinol carbamate) is an orally active 2,6-pyridine dimethanol biscarbamate with cholesterol-lowering and antiatherosclerotic effects .
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3-Pyridinemethanol (Nicotinyl alcohol), a pyridine derivative, is a cholesterol-lowering agent. 3-Pyridinemethanol can be selectively oxidized to vitamin B3 .
Cat. No.: HY-178015
CAS No.: 3051970-23-8
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THR-β agonist 11 is an orally active and selective thyroid hormone receptor (THR-β) agonist. THR-β agonist 11 shows potent cholesterol-lowering activity in cholesterol-fed rats. THR-β agonist 11 significantly reduces serum total TG, LDL-cholesterol, liver total TC and TG levels, and alleviates hepatic steatosis, inflammation and fibrosis in HFD-CCl4-induced Metabolic dysfunction-associated steatohepatitis (MASH) model mice. THR-β agonist 11 can be used for the study of metabolic dysfunction-associated steatohepatitis (MASH) and other fibrotic diseases .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
