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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
25 Results for "
cholesteryl ester transfer
" in MedChemExpress (MCE) Product Catalog:
Products (25)
25 Results for "cholesteryl ester transfer" in MCE Product Catalog:
2
2 Cited Publications
Synonyms: JTT-705; RO4607381
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Dalcetrapib (JTT-705) is an orally active cholesteryl ester transfer protein (CETP) inhibitor with IC50s of 204.6 nM and 6 μM against recombinant human (rh) CETP and human plasma CETP, respectively .
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Obicetrapib (TA-8995; DEZ-001) is an orally active cholesteryl ester transfer protein (CETP) inhibitor. Obicetrapib potently reduces atherogenic lipoproteins (such as LDL-C, ApoB, Lp (a)) and increases HDL-C. Obicetrapib can be used for the research of dyslipidemia and atherosclerotic cardiovascular disease (ASCVD) .
Synonyms: CP-529414
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Torcetrapib (CP-529414) is a selective, potent cholesteryl ester transfer protein (CETP) inhibitor. A typical inhibition curve for whole human plasma, having a CETP concentration of 37 nM .
Cat. No.: HY-149037A
Purity: 98.60%
Synonyms: N4-Spermine cholesteryl carbamate pentahydrochloride
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GL67 pentahydrochloride (N4-Spermine cholesteryl carbamate pentahydrochloride) is a cationic lipid that serves as a non-viral siRNA delivery vector and a non-viral gene transfer vector. GL67 pentahydrochloride enhances the encapsulation efficiency of siRNA in liposomal formulations and promotes the cellular uptake of siRNA across cancer cell membranes. GL67 pentahydrochloride mediates the transduction of plasmid DNA into cells. GL67 pentahydrochloride can be used in drug delivery-related research .
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CKD-519 is a selective and potent cholesteryl ester transfer protein (CETP) inhibitor, which inhibits CETP-mediated transfer of cholesteryl ester in human serum with an IC50 of 2.3 nM .
Cat. No.: HY-W414588
CAS No.: 50673-97-7
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Colestolone is a 15-ketosterol compound and an orally active inhibitor of HMG-CoA reductase. Colestolone can inhibit the activity of cholesteryl ester transfer protein (CETP) in vitro (IC50 = 660 μM). Colestolone is a cholesterol-lowering agent, and can be used in the research of endocrine and metabolic diseases such as hyperlipidemia .
Cat. No.: HY-W015752
CAS No.: 2174-64-3
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Cat. No.: HY-149037
CAS No.: 179075-30-0
Synonyms: N4-Spermine cholesteryl carbamate
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GL67 (N4-Spermine cholesteryl carbamate) is a cationic lipid that serves as a non-viral siRNA delivery vector and a non-viral gene transfer vector. GL67 enhances the encapsulation efficiency of siRNA in liposomal formulations and promotes the cellular uptake of siRNA across cancer cell membranes. GL67 mediates the transduction of plasmid DNA into cells. GL67 can be used in drug delivery-related research .
Cat. No.: HY-107997
CAS No.: 1149362-88-8
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TAP311 is a cholesteryl ester transfer protein (CETP) inhibitor with an IC50 of 62 nM .
Cat. No.: HY-19614
CAS No.: 939390-99-5
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BMS-795311 is a potent and orally bioavailable inhibitor of cholesteryl ester transfer protein (CETP), with IC50s of 4 nM in an enzyme-based scintillation proximity assay (SPA) and 0.22 μM in a human whole plasma assay (hWPA), respectively .
Cat. No.: HY-105316
CAS No.: 263262-73-3
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CP-800569 is an orally active cholesteryl ester transfer protein (CETP) inhibitor. CP-800569 can decrease low-density lipoprotein and postprandial triglyceride and increase high-density lipoprotein. CP-800569 can be used for the research of metabolic disease .
Cat. No.: HY-142643
CAS No.: 1648889-70-6
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CETP-IN-4 is a cholesteryl ester transfer protein (CETP) inhibitor.
Cat. No.: HY-169723
CAS No.: 262352-13-6
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CP 524515 is a potent inhbitor of cholesteryl ester transfer protein (CETP) that leads to elevated high-density lipoprotein cholesterol levels .
Cat. No.: HY-132303
CAS No.: 1432054-03-9
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MK-8262 is an orally active and potent cholesteryl ester transfer protein (CETP) inhibitor with an IC50 of 53 nM and a log D of 5.3. MK-8262, a bistrifluoromethyl analogue, has the potential for coronary heart disease (CHD) correlated high-density lipoprotein (HDL) and low-density lipoprotein (LDL) research .
Cat. No.: HY-14950R
CAS No.: 211513-37-0
Synonyms: JTT-705 (Standard); RO4607381 (Standard)
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Dalcetrapib (Standard) is the analytical standard of Dalcetrapib. This product is intended for research and analytical applications. Dalcetrapib (JTT-705) is an orally active cholesteryl ester transfer protein (CETP) inhibitor with IC50s of 204.6 nM and 6 μM against recombinant human (rh) CETP and human plasma CETP, respectively .
Cat. No.: HY-W015752R
CAS No.: 2174-64-3
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Cat. No.: HY-N8353
CAS No.: 149598-71-0
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Cat. No.: HY-136993
CAS No.: 949099-81-4
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(S)-PF-04445597 is an orally active cholesteryl ester transfer protein (CETP) inhibitor with an IC50 of 0.07 μM. (S)-PF-04445597 inhibits CETP-mediated transfer of cholesteryl esters from HDL to non-HDL lipoproteins. (S)-PF-04445597 can be used for research on coronary heart disease .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
