country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

5 Results for "

choline uptake

" in MedChemExpress (MCE) Product Catalog:

Products (5)

Sort by :

Categories

By Targets

Products

Coluracetam

3 Cited Publications

Cat. No.: HY-17553

CAS No.: 135463-81-9

Synonyms: MKC-231

Target:

iGluR

Research Areas:

Neurological Disease

Coluracetam (MKC-231) is an orally taken choline uptake enhancer. Coluracetam can improve the reduced acetylcholine levels in the hippocampus of rats and mice, enhancing learning difficulties, memory deficits, and cognitive impairments. Coluracetam induces a lower degree of hepatic venous hyperglycemia .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

ICL-CCIC-0019

Cat. No.: HY-115840

CAS No.: 936498-64-5

Target:

Apoptosis AMPK Caspase

Research Areas:

Cancer

ICL-CCIC-0019 is a CHKA inhibitor with a human IC₅₀ of 270 nM. ICL-CCIC-0019 blocks choline phosphorylation and phosphatidylcholine synthesis via the CDP-choline pathway. ICL-CCIC-0019 inhibits choline uptake, mitochondrial respiration, TCA cycle flux, de novo fatty acid synthesis, and mitochondrial membrane potential, while inducing G1 phase arrest, ER stress, caspase-dependent apoptosis, AMPK activation, glycolysis, acetate uptake, and mitochondrial network disruption. ICL-CCIC-0019 can be used for cancer research .

Compare