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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
35 Results for "
collagen IV
" in MedChemExpress (MCE) Product Catalog:
Products (35)
35 Results for "collagen IV" in MCE Product Catalog:
22
Collagenase, Type IV (EC 3.4.24.3) is a microbially derived matrix metalloproteinases (MMPs) and zinc peptidase. Collagenase, Type IV degrades type IV collagen and type VII collagen, the main components of the basement membrane, and can also decompose basement matrix and elastin.
8
8 Cited Publications
Cat. No.: HY-P81227
Synonyms: collagen type I; Alpha 1 type I collagen; Alpha 2 type I collagen; COL1A1; COL1A2; collagen I alpha 1 polypeptide; collagen I alpha 2 polypeptide; collagen Of Skin Tendon And Bone; collagen Type 1; collagen type I alpha 1; collagen type I alpha 2; OI4; Osteogenesis Imperfecta Type IV; Pro alpha 1(I) collagen; Type I procollagen; CO1A1_HUMAN.
4
4 Cited Publications
Cat. No.: HY-P1408
CAS No.: 404882-00-4
4
4 Cited Publications
Cat. No.: HY-P1408A
2
2 Cited Publications
Cat. No.: HY-P81101
Synonyms: COL 3A1; COL3A1; collagen alpha 1(III) chain; collagen III alpha 1 chain precursor; collagen III alpha 1 polypeptide; collagen type III alpha 1 (Ehlers Danlos syndrome type IV autosomal dominant); collagen type III alpha 1; collagen type III alpha; EDS4A; Ehlers Danlos syndrome type IV, autosomal dominant; Fetal collagen; Type III collagen; CO3A1_HUMAN; collagen alpha-1(III) chain; Type III collagen; type III preprocollagen alpha 1 chain.
2
2 Cited Publications
Cat. No.: HY-P81793
Synonyms: CD36; GP3B; GP4; Platelet glycoprotein 4; Fatty acid translocase; FAT; Glycoprotein IIIb; GPIIIB; Leukocyte differentiation antigen CD36; PAS IV; PAS-4; Platelet collagen receptor; Platelet glycoprotein IV; GPIV; Thrombospondin receptor; CD36
1
1 Cited Publications
Target:
Research Areas:
VU6015929 is a potent, selective and orally active dual discoidin domain receptor 1/2 (DDR1/2) inhibitor with IC50s of 4.67 nM and 7.39 nM, respectively. VU6015929 potently blocks collagen-induced DDR1 activation and collagen-IV production .
1
1 Cited Publications
Cat. No.: HY-P81201
Synonyms: Arresten; Canstatin; COL4A1; HANAC; ICH; POREN1; collagen Alpha 1(IV) Chain; collagen IV Alpha 1 Polypeptide; collagen Of Basement Membrane Alpha 1 Chain; collagen Of Basement Membrane Alpha 2 Chain; collagen Type IV Alpha 1; DKFZp686I14213; FLJ22259; collagen alpha-1(IV) chain preproprotein; collagen alpha-1(IV) chain preproprotein; Col4a1 protein; collagen of basement membrane, alpha-1 chain; collagen IV, alpha-1 polypeptide; collagen alpha-1(IV) chain; COL4A1 NC1 domain; CO4A1_HUMAN; collagen Ⅳ; collagen Type Ⅳ.
1
1 Cited Publications
Cat. No.: HY-P86458
Synonyms: CD36; GP3B; GP4; Platelet glycoprotein 4; Fatty acid translocase; FAT; Glycoprotein IIIb; GPIIIB; Leukocyte differentiation antigen CD36; PAS IV; PAS-4; Platelet collagen receptor; Platelet glycoprotein IV; GPIV; Thrombospondin receptor; CD36
Cat. No.: HY-131577A
CAS No.: 42613-33-2
Synonyms: Dispase I
Neutral protease I (Dispase I) is a rapid, effective, gentle and neutral protease that can separate intact epidermis from the dermis. Neutral protease I can also separate intact epithelial sheets in culture from the substratum. Neutral protease I preserves the viability of the epithelial cells while cleaving the basement membrane zone region. Neutral protease I can also be used to prevent clumping in suspension cultures. Neutral protease I cleaves fibronectin and type IV collagen, but not laminin, type V collagen, serum albumin, or transferrin .
Cat. No.: HY-P10709
CAS No.: 847058-45-1
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Research Areas:
Cat. No.: HY-P3369
CAS No.: 2417491-82-6
Synonyms: AXT-107
Research Areas:
Cardiovascular Disease Metabolic Disease Inflammation/Immunology
Cat. No.: HY-W442049
CAS No.: 893412-73-2
Synonyms: HPR
Target:
Research Areas:
Hydroxypinacolone retinoate (HPR) is a direct-binding agonist of retinoic acid receptor (RAR). Hydroxypinacolone retinoate has low irritation and high stability; when formulated into nanoparticles, its transdermal efficiency is enhanced, allowing it to penetrate deep into the dermis and achieve sustained release. When used in combination with Retinyl propionate, hydroxypinacolone retinoate promotes fibroblast proliferation and upregulates the gene expression of type IV collagen, CRBP-I and RARB. Hydroxypinacolone retinoate can be used in research related to skin wrinkles and skin aging .
Cat. No.: HY-171657
CAS No.: 411233-11-9
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4'-Acetoxy resveratrol is a Resveratrol (HY-16561) derivative. 4'-Acetoxy resveratrol upregulates gene expression of elastin, collagen types III and IV, superoxide dismutase (SOD), and catalase (CAT), while downregulating interleukins (IL-1A, IL-1R2, IL-6, IL-8) and cyclooxygenase-2 (COX-2) in human skin models. 4'-Acetoxy resveratrol can be used for skin reasearch .
Cat. No.: HY-P11794A
Cat. No.: HY-P11794
CAS No.: 119975-51-8
Cat. No.: HY-NP231
Target:
Research Areas:
Collagen type IV, from human is a basement membrane extracellular matrix component. Collagen type IV, from human can be used as a coating substrate for cell culture dishes for hiPSC-LSC culture and expansion. Collagen type IV, from human is used as an antigen in home-ELISA for the detection of anti-Collagen IV autoantibodies .
Cat. No.: HY-174719
Target:
Research Areas:
Human ELANE mRNA encodes the human elastase (ELANE) protein, a member of serine proteases family. ELANE may play a role in degenerative and inflammatory diseases through proteolysis of collagen-IV and elastin.
Cat. No.: HY-174313
Research Areas:
Antibacterial agent 284 (Compound 7) is an Antibacterial agent. Antibacterial agent 284 has a zinc-binding structure and potent inhibitory activity against Legionella pneumophila metalloprotease ProA (IC50: 0.96 μM) with zinc-binding structure. Antibacterial agent 284 significantly inactivates the cleavage of collagen IV and flagellin (ProA substrates) and reduces immune evasion from the TLR5-NF-κB pathway and PMN-mediated inflammation in human lung tissue explants. Antibacterial agent 284 is promising for Legionnaires' disease research .
Cat. No.: HY-P86639
Synonyms: Arresten; BSVD; CO4A1_HUMAN; COL4A1; COL4A1 NC1 domain; COL4A2; COL4A3; COL4A4; COL4A5; collagen alpha-1; IV; chain; collagen IV Alpha 1 Polypeptide; collagen IV Alpha 2 Polypeptide; collagen Of Basement Membrane Alpha 1 Chain; collagen Of Basement Membrane Alpha 2 Chain; collagen Type IV Alpha 1; collagen type IV alpha 1 chain; collagen Type IV Alpha 2; collagen Type IV Alpha 3; collagen Type IV Alpha 4; collagen Type IV Alpha 5; RatOR
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
