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6 Results for "

common cold

" in MedChemExpress (MCE) Product Catalog:

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LEI110

1 Cited Publications

Cat. No.: HY-125254

CAS No.: 2313525-90-3

Purity: 99.72%

Target:

HRASLS Phospholipase

Research Areas:

Metabolic Disease Cancer

LEI110 is a pan-inhibitor of the HRASLS family and an inhibitor of AP-2α, with a K_i of 20 nM against PLA2G16. LEI110 exhibits inhibitory activity against PLA2G16, HRASLS2, RARRES3 and iNAT, with pIC₅₀ values of 7.0, 6.8, 6.8 and 7.6, respectively. LEI110 binds to the active site of PLA2G16, reduces intracellular arachidonic acid levels, and attenuates oleic acid-induced lipolysis. LEI110 stabilizes AP-2α, impairs its DNA-binding ability, inhibits the transcription of DNA damage repair genes, induces the accumulation of oxidative DNA damage, suppresses cell proliferation and clonogenicity, and sensitizes HCC cells to DNA-damaging agents. LEI110 can be used in research related to obesity, fatty liver disease, the common cold and hepatocellular carcinoma .

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Zinc acetate dihydrate, ACS, 98%

Cat. No.: HY-B0658A

CAS No.: 5970-45-6

Synonyms: Zinc(II) acetate dihydrate, ACS, 98%

Zinc acetate dihydrate, ACS, 98% (Zinc (II) acetate dihydrate, ACS, 98%) acts as a metal chelator and an intestinal metallothionein inducer. Zinc acetate dihydrate, ACS, 98% induces intestinal metallothionein synthesis and shortens the course of the common cold. Zinc acetate dihydrate, ACS, 98% is applicable to the research of copper metabolism disorder-related diseases, the common cold and Wilson's disease, as well as protein experiments .

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