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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10194 Results for "
computationally designed peptides
" in MedChemExpress (MCE) Product Catalog:
Products (10194)
10194 Results for "computationally designed peptides" in MCE Product Catalog:
266
266 Publications Verification
Synonyms: Angiotensin II; Ang II; DRVYIHPF
Target:
139
139 Cited Publications
Cat. No.: HY-P1410
CAS No.: 1209500-46-8
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Cardiovascular Disease Neurological Disease Inflammation/Immunology
139
139 Cited Publications
Cat. No.: HY-P1410A
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Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology
83
83 Cited Publications
Cat. No.: HY-K1057
Puromycin is an aminonucleoside antibiotic produced by Streptomyces alboniger. It inhibits protein synthesis by disrupting peptide transfer on ribosomes, causing premature chain termination during translation. It can kill most gram-positive bacteria and various animal or insect cells.
72
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Exendin‑4 (Exenatide) is an orally active, blood-brain barrier-permeable glucagon-like peptide-1 receptor (GLP‑1 receptor) agonist that resists degradation mediated by dipeptidyl peptidase IV. Exendin‑4 mediates multiple glucose-regulating effects, including stimulation of glucose-dependent insulin secretion, inhibition of glucagon production, increase in β-cell mass, delay of gastric emptying, reduction of food intake, improvement of peripheral insulin sensitivity, and restoration of normal islet structure. Exendin‑4 inhibits oxidative stress, alleviates inflammatory responses, and reduces neuronal apoptosis. Exendin‑4 reduces the aggregation level of mutant huntingtin, improves motor function, prolongs survival time, and regulates the expression levels of leptin and ghrelin. Exendin‑4 can be used in research related to type 2 diabetes, acute ischemic stroke, and Huntington's disease .
71
71 Cited Publications
Cat. No.: HY-K2014
MCE PEI Transfection Reagent is designed based on 25 kDa PEI. It has high-efficiency, low-toxicity, strong-stability, and is suitable for many cell types, such as HEK-293、HEK-293T、CHO-K1、COS-1、COS-7、NIH/3T3、Sf9、HepG2 and HeLa et, even some hard-to-transfect cells. It can also be applied to large-scale recombinant protein expression and virus production. The 1 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
51
51 Cited Publications
Cat. No.: HY-P0128
CAS No.: 131602-53-4
Synonyms: Amyloid beta-peptide (25-35); Aβ25-35; β-Amyloid peptide (25-35)
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51
51 Cited Publications
Cat. No.: HY-P0128A
CAS No.: 131602-53-4
Synonyms: Amyloid beta-peptide (25-35), HFIP-treated; Aβ25-35, HFIP-treated; β-Amyloid peptide (25-35), HFIP-treated
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46
46 Cited Publications
Cat. No.: HY-K0030
MCE Deacetylase Inhibitor Cocktail is a synergistic combination of chemicals designed to preserve the acetylation state of proteins.The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
43
43 Cited Publications
Cat. No.: HY-P0014
CAS No.: 204656-20-2
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Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology
43
43 Cited Publications
Cat. No.: HY-P0014B
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42
36
36 Cited Publications
Cat. No.: HY-P0319
CAS No.: 402750-12-3
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36
36 Cited Publications
Cat. No.: HY-P0319A
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31
31
31 Cited Publications
Synonyms: α-Hypophamine acetate; Oxytocic hormone acetate
30
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β-Amyloid (1-42) (Amyloid β-peptide (1-42), human TFA, a 42-amino acid peptide that has not been treated with HFIP, is a brain-penetrant amyloid protein fragment, which can be used in research on Alzheimer's disease and Down’s syndrome. β-Amyloid (1-42), human TFA remaining as a monomer exhibits antioxidant and neuroprotective effects. β-Amyloid (1-42), human TFA, after being monomericized by HFIP and dissolved in DMSO to form the stock solution, on the one hand, can form soluble oligomers (AβOs) when incubated at 4 °C, which have synaptic toxicity and neurotoxicity; on the other hand, it can be incubated at 37 °C to form insoluble fibrils, with lower neurotoxicity, and participating in the oxidative damage process. Aβ42 oligomers bind to various neuronal surface receptors (such as PrPc, mGluR5, NMDA receptors, etc.), triggering oxidative stress, calcium homeostasis imbalance, and synaptic toxicity via activating downstream signaling pathways, leading to neuronal dysfunction and death .
27
27 Cited Publications
Cat. No.: HY-P0223
CAS No.: 98849-88-8
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27
27 Cited Publications
Cat. No.: HY-P1489
CAS No.: 138831-86-4
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27
27 Cited Publications
Cat. No.: HY-P1489A
CAS No.: 1262751-08-5
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
