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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
27 Results for "
cone
" in MedChemExpress (MCE) Product Catalog:
Products (27)
27 Results for "cone" in MCE Product Catalog:
1
1 Cited Publications
Category:
Plant Flavonoids Chalcones Moraceae Extract Phenols Polyphenols Disease Research Fields Humulus lupulus L. Extract Cancer
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Pregnenolone acetate (compound #43), a nonmetabolized Pregnenolone (HY-B0151) analog, can promote neurite extension and induce a change in growth cone morphology in primary cultures of cerebellar granule neurons. Pregnenolone acetate, a neurosteroid, increases microtubule polymerization. Pregnenolone acetate has the potential for neurodevelopmental diseases research .
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TCS1105 is a benzodiazepine ligand with agonist for α2-subunit containing GABAA receptors and antagonist for α1-subunit containing GABAA receptors. TCS1105 reduces anxiety-like behavior in mice. TCS1105 enhances offensive behavior and social dominance. TCS1105 blocks Sema3A induced AGC (axonal growth cones) collapse in a concentration-dependent fashion .
Cat. No.: HY-N14827
CAS No.: 151466-15-8
Synonyms: SM-216289
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AA41612 is a melanopsin (Opn4) inhibitor with an IC50 of 15.8 nM, a Ki of 0.43 nM, and a Kd of 0.28 nM. AA41612 competes with retinal for binding to melanopsin, blocks melanopsin activation, and inhibits melanopsin-mediated phototransduction processes without affecting rod- and cone-mediated responses. AA41612 attenuates light-induced melanopsin photocurrents, reduces light-induced cytoplasmic calcium elevation, and weakens high-irradiance pupillary light reflex in mice with induced classical photoreceptor degeneration. AA41612 can be used in studies related to migraine and photophobia .
Cat. No.: HY-NP0138
Synonyms: PNA (Fluorescein)
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Peanut Agglutinin (PNA) Fluorescein is a fluorescently labeled lectin that specifically binds to glycosylated cells and Haemonchus contortus. Peanut Agglutinin Fluorescein specifically recognizes and binds to the D-Gal-β(1→3)-D-GalNAc disaccharide sequence and terminal D-galactosyl residues on the cell surface; its binding can be inhibited by D-galactose but is not affected by glucose. Peanut Agglutinin Fluorescein specifically labels cone photoreceptor segments and can also be used to distinguish immature thymocytes from lymphocyte subsets, serving as an effective tool for studying cellular glycosylation status and isolating specific cell populations .
Cat. No.: HY-P11035
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APY-d3 is a highly selective EphA4 receptor inhibitor, with an IC50 value of 17-56 nM for human EphA4, an IC50 value of 20 nM for mouse EphA4, and a Kd value of 138 nM for EphA4-LBD. APY-d3 binds to EphA4, blocks its interaction with ephrin ligands, inhibits tyrosine phosphorylation of EphA4, prevents growth cone collapse, and does not induce EphA4 phosphorylation in primary cortical neurons. APY-d3 adopts a β-hairpin conformation stabilized by an N-terminal to C-terminal disulfide bond. APY-d3 can be used in research related to amyotrophic lateral sclerosis, Alzheimer's disease, stroke, neurodegenerative diseases and cancer .
Cat. No.: HY-P1287
CAS No.: 127476-26-0
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Cat. No.: HY-N7178
CAS No.: 337527-10-3
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Cat. No.: HY-178919
CAS No.: 2996841-28-0
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N-19004 is a FPR1 antagonist. N-19004 shows broad-spectrum antibacterial effects against a variety of pathogens. N-19004 exhibits significant retinal protective effects in the rd10 mouse model of retinitis pigmentosa (RP). N-19004 can attenuate retinal dysfunction, mitigate rod and cone degeneration, and reduce immune cell activation, gliosis, inflammation, oxidative stress, and apoptosis. N-19004 can reduce the size of laser-induced choroidal lesions and promote edema absorption through dual anti-inflammatory and anti-angiogenic effects. N-19004 can be used for the research of retinal degenerative diseases such as retinitis pigmentosa .
Cat. No.: HY-N3612A
CAS No.: 10178-32-2
Synonyms: (-)-Communic acid
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Chamaecyparis obtusa (Siebold & Zucc.) Endl. Extract Plant Terpenoids Sesquiterpenes Cupressaceae Extract
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Cat. No.: HY-N13186
CAS No.: 1639050-37-5
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Natural Products Plant Guttiferae Extract Garcinia amplexicaulis Vieill. ex Pierre Extract
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Cat. No.: HY-W587807
CAS No.: 22737-96-8
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11-cis-Retinol, a form of retinol, can bind to RDH5. 11-cis-Retinol promote dark adaptation and recovery of photoresponsiveness of red cones but not of red rods .
Cat. No.: HY-N11976
CAS No.: 1186016-30-7
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Leguminosae/Fabaceae Extract Plant Ketones, Aldehydes, Acids Glycyrrhiza glabra Linn. Extract
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Cat. No.: HY-P86825
Synonyms: cone rod homeobox antibody; cone rod homeobox protein antibody; cone rod homeobox-containing gene antibody; cone-rod homeobox antibody; cone-rod homeobox protein antibody; CORD 2 antibody; CRD antibody; CRX antibody; CRX_HUMAN antibody; LCA 7 antibody; cone rod homeobox antibody; cone rod homeobox protein antibody; cone rod homeobox-containing gene antibody; cone-rod homeobox antibody; cone-rod homeobox protein antibody; CORD 2 antibody; CRD antibody; CRX antibody; CRX_HUMAN antibody; LCA 7 antibody; LCA7 antibody; Orthodenticle homeobox 3 antibody; OTX 3 antibody; OTX3 antibody;
Cat. No.: HY-P702398
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: OPN1LW; COD5; Prev. RCP; Long-Wave-Sensitive Opsin 1; Prev. CBBM; Red-Sensitive Opsin; Prev. CBP; ROP; Opsin 1 (cone Pigments), Long-Wave-Sensitive; Color Blindness, Protan; Red cone Photoreceptor Pigment; Red cone Opsin; Opsin 1, Long Wave Sensitive; Con
Species:
Human
Source:
E. coli Cell-free
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
