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213 Results for "

cord

" in MedChemExpress (MCE) Product Catalog:

Products (213)

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TGN-020

26 Publications Verification

Cat. No.: HY-W008574

CAS No.: 51987-99-6

Target:

PROTAC Linkers

Research Areas:

Inflammation/Immunology Cancer

TGN-020 is a selective Aquaporin 4 (AQP4) inhibitor with an IC₅₀ of 3.1 μM . TGN-020 is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .TGN-020 alleviates edema and inhibits glial scar formation after spinal cord compression injury in rats .

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TGN-020 sodium

26 Publications Verification

Cat. No.: HY-W008574A

CAS No.: 1313731-99-5

Target:

PROTAC Linkers

Research Areas:

Inflammation/Immunology Cancer

TGN-020 sodium is a selective Aquaporin 4 (AQP4) inhibitor with an IC₅₀ of 3.1 μM . TGN-020 sodium is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . TGN-020 sodium alleviates edema and inhibits glial scar formation after spinal cord compression injury in rats .

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Z-LEHD-FMK

16 Cited Publications

Cat. No.: HY-P1010

CAS No.: 210345-04-3

Target:

Caspase Apoptosis

Research Areas:

Neurological Disease Cancer

Z-LEHD-FMK is a selective and irreversible inhibitor of caspase-9, protects against lethal reperfusion injury and attenuates apoptosis. Z-LEHD-FMK exhibits the neuroprotective effect in a rat model of spinal cord trauma .

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Naloxone hydrochloride

10 Cited Publications

Cat. No.: HY-17417

CAS No.: 357-08-4

Target:

Opioid Receptor

Research Areas:

Neurological Disease

Naloxone hydrochloride is an orally active opioid receptor antagonist. Naloxone hydrochloride attenuates spinal cord stimulation‑associated anti‑hyperalgesic effects, antagonizes physiologic effects of endogenous opioid peptides linked to central nervous system injury sequelae, functions as a pressor agent to induce modest elevations in mean arterial blood pressure, exerts neuroprotective effects to improve post‑traumatic neurologic motor function, blocks opioid receptor‑mediated amnesic pathways, enhances memory consolidation, reverses Adrenocorticotropic hormone (ACTH) (HY-106373)- and epinephrine‑induced amnesia, and potentiates the memory‑facilitatory effects of ACTH and epinephrine .

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Naloxone

10 Cited Publications

Cat. No.: HY-17417A

CAS No.: 465-65-6

Target:

Opioid Receptor

Research Areas:

Neurological Disease

Naloxone hydrochloride is an orally active opioid receptor antagonist. Naloxone hydrochloride attenuates spinal cord stimulation‑associated anti‑hyperalgesic effects, antagonizes physiologic effects of endogenous opioid peptides linked to central nervous system injury sequelae, functions as a pressor agent to induce modest elevations in mean arterial blood pressure, exerts neuroprotective effects to improve post‑traumatic neurologic motor function, blocks opioid receptor‑mediated amnesic pathways, enhances memory consolidation, reverses Adrenocorticotropic hormone (ACTH) (HY-106373)‑ and epinephrine‑induced amnesia, and potentiates the memory‑facilitatory effects of ACTH and epinephrine .

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TCID

7 Cited Publications

Cat. No.: HY-18638

CAS No.: 30675-13-9

Synonyms: 4,5,6,7-Tetrachloroindan-1,3-dione

Target:

Deubiquitinase

Research Areas:

Neurological Disease

TCID (4,5,6,7-Tetrachloroindan-1,3-dione) is a potent and selective neuronal ubiquitin C-terminal hydrolase (UCH-L3) inhibitor with an IC₅₀ of 0.6 μM . TCID diminishes glycine transporter GlyT2 ubiquitination in brainstem and spinal cord primary neurons .

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